Search Results - "Johnson, Gail M"

Glutathione sulfinamide serves as a selective, endogenous biomarker for nitroxyl after exposure to therapeutic levels of donors by Johnson, Gail M, Chozinski, Tyler J, Gallagher, Elyssia S, Aspinwall, Craig A, Miranda, Katrina M

“…Nitroxyl (HNO) donors exhibit promising pharmacological characteristics for treatment of cardiovascular disorders, cancer, and alcoholism. However, whether HNO…”
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Quantitative Detection of Nitroxyl Upon Trapping with Glutathione and Labeling with a Specific Fluorogenic Reagent by Johnson, Gail M., Chozinski, Tyler J., Salmon, Debra J., Moghaddam, Alan D., Chen, Hsin Chih, Miranda, Katrina M.

“…Donors of nitroxyl (HNO) have shown promise for treatment of stroke, heart failure, alcoholism and cancer. However, comparing the pharmacological capacities of…”
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Enhancing the Dissolution Stability of Hard Gelatin Capsules Using Activated Carbon as a Packaging Component by Likar, Michael D, Carroll, Sophia C, Colgan, Stephen T, Yeoh, Thean, MacDonald, Bruce C, Johnson, Gail M, Space, J Sean

“…Hard gelatin capsule (HGC) shells are widely used to encapsulate drugs for oral delivery but are vulnerable to gelatin cross-linking, which can lead to slower…”
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Use of Activated Carbon in Packaging to Attenuate Formaldehyde-Induced and Formic Acid-Induced Degradation and Reduce Gelatin Cross-Linking in Solid Dosage Forms by Colgan, Stephen T, Zelesky, Todd C, Chen, Raymond, Likar, Michael D, MacDonald, Bruce C, Hawkins, Joel M, Carroll, Sophia C, Johnson, Gail M, Space, J Sean, Jensen, James F, DeMatteo, Vincent A

“…Formaldehyde and formic acid are reactive impurities found in commonly used excipients and can be responsible for limiting drug product shelf-life. Described…”
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Analysis of the HNO and NO donating properties of alicyclic amine diazeniumdiolates by Bharadwaj, Gaurav, Benini, Patricia G.Z., Basudhar, Debashree, Ramos-Colon, Cyf N., Johnson, Gail M., Larriva, Marti M., Keefer, Larry K., Andrei, Daniela, Miranda, Katrina M.

“…•Primary alicyclic amine-based diazeniumdiolates function as HNO donors.•These compounds extend the range of known diazeniumdiolate-based HNO donors.•An…”
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Glutathione Sulfinamide Serves as a Selective, Endogenous Biomarker for Nitroxyl Following Exposure to Therapeutic Levels of Donors by Johnson, Gail M., Chozinski, Tyler J., Gallagher, Elyssia S., Aspinwall, Craig A., Miranda, Katrina M.

“…Nitroxyl (HNO) donors exhibit promising pharmacological characteristics for treatment of cardiovascular disorders, cancer and alcoholism. However, whether HNO…”
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Corrigendum to ‘Quantitative Detection of Nitroxyl Upon Trapping with Glutathione and Labeling with a Specific Fluorogenic Reagent’ [Free Radical Biology and Medicine 63(2013) 476–484] by Johnson, Gail M., Chozinski, Tyler J., Salmon, Debra J., Moghaddam, Alan D., Chen, Hsin Chih, Miranda, Katrina M.

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