Search Results - "Johnson, F."

Constructing Experimental Designs for Discrete-Choice Experiments: Report of the ISPOR Conjoint Analysis Experimental Design Good Research Practices Task Force by Reed Johnson, F., PhD, Lancsar, Emily, PhD, Marshall, Deborah, PhD, Kilambi, Vikram, BA/BS, Mühlbacher, Axel, PhD, Regier, Dean A., PhD, Bresnahan, Brian W., PhD, Kanninen, Barbara, PhD, Bridges, John F.P., PhD

“…Abstract Stated-preference methods are a class of evaluation techniques for studying the preferences of patients and other stakeholders. While these methods…”
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Methionine restriction activates the retrograde response and confers both stress tolerance and lifespan extension to yeast, mouse and human cells by Johnson, Jay E, Johnson, F Brad

“…A methionine-restricted diet robustly improves healthspan in key model organisms. For example, methionine restriction reduces age-related pathologies and…”
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Potential Roles for G-Quadruplexes in Mitochondria by Falabella, Micol, Fernandez, Rafael J, Johnson, F Brad, Kaufman, Brett A

“…Some DNA or RNA sequences rich in guanine (G) nucleotides can adopt noncanonical conformations known as G-quadruplexes (G4). In the nuclear genome, G4 motifs…”
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Dietary restraint and self-regulation in eating behavior by Johnson, F, Pratt, M, Wardle, J

“…Self-control is generally viewed as highly desirable. In the eating behavior domain, however, the dominance of restraint theory has made the proposition that…”
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The online competition between pro- and anti-vaccination views by Johnson, Neil F., Velásquez, Nicolas, Restrepo, Nicholas Johnson, Leahy, Rhys, Gabriel, Nicholas, El Oud, Sara, Zheng, Minzhang, Manrique, Pedro, Wuchty, Stefan, Lupu, Yonatan

“…Distrust in scientific expertise 1 – 14 is dangerous. Opposition to vaccination with a future vaccine against SARS-CoV-2, the causal agent of COVID-19, for…”
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Epigenetic Mechanisms Impacting Aging: A Focus on Histone Levels and Telomeres by Song, Shufei, Johnson, F Brad

“…Aging and age-related diseases pose some of the most significant and difficult challenges to modern society as well as to the scientific and medical…”
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Detection of G-quadruplex DNA in mammalian cells by Henderson, Alexander, Wu, Yuliang, Huang, Yu Chuan, Chavez, Elizabeth A, Platt, Jesse, Johnson, F Brad, Brosh, Jr, Robert M, Sen, Dipankar, Lansdorp, Peter M

“…It has been proposed that guanine-rich DNA forms four-stranded structures in vivo called G-quadruplexes or G4 DNA. G4 DNA has been implicated in several…”
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TERRA G-quadruplex RNA interaction with TRF2 GAR domain is required for telomere integrity by Mei, Yang, Deng, Zhong, Vladimirova, Olga, Gulve, Nitish, Johnson, F. Brad, Drosopoulos, William C., Schildkraut, Carl L., Lieberman, Paul M.

“…Telomere dysfunction causes chromosomal instability which is associated with many cancers and age-related diseases. The non-coding telomeric repeat-containing…”
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Reliability and validity of a revised version of the General Nutrition Knowledge Questionnaire by Kliemann, N, Wardle, J, Johnson, F, Croker, H

“…Background/Objectives: The General Nutrition Knowledge Questionnaire (GNKQ) was developed in the 1990s and has been widely used. Since then advances in…”
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Future changes to the intensity and frequency of short-duration extreme rainfall by Westra, S., Fowler, H. J., Evans, J. P., Alexander, L. V., Berg, P., Johnson, F., Kendon, E. J., Lenderink, G., Roberts, N. M.

“…Evidence that extreme rainfall intensity is increasing at the global scale has strengthened considerably in recent years. Research now indicates that the…”
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The Internal Validity of Discrete Choice Experiment Data: A Testing Tool for Quantitative Assessments by Johnson, F. Reed, Yang, Jui-Chen, Reed, Shelby D.

“…To develop a tool for testing internal validity of discrete choice experiment (DCE) data, deploy the program, and collect summary test results from a sample of…”
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Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia by Fraietta, Joseph A., Lacey, Simon F., Orlando, Elena J., Pruteanu-Malinici, Iulian, Gohil, Mercy, Lundh, Stefan, Boesteanu, Alina C., Wang, Yan, O’Connor, Roddy S., Hwang, Wei-Ting, Pequignot, Edward, Ambrose, David E., Zhang, Changfeng, Wilcox, Nicholas, Bedoya, Felipe, Dorfmeier, Corin, Chen, Fang, Tian, Lifeng, Parakandi, Harit, Gupta, Minnal, Young, Regina M., Johnson, F. Brad, Kulikovskaya, Irina, Liu, Li, Xu, Jun, Kassim, Sadik H., Davis, Megan M., Levine, Bruce L., Frey, Noelle V., Siegel, Donald L., Huang, Alexander C., Wherry, E. John, Bitter, Hans, Brogdon, Jennifer L., Porter, David L., June, Carl H., Melenhorst, J. Joseph

“…Tolerance to self-antigens prevents the elimination of cancer by the immune system 1 , 2 . We used synthetic chimeric antigen receptors (CARs) to overcome…”
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A cargo-sorting DNA robot by Thubagere, Anupama J., Li, Wei, Johnson, Robert F., Chen, Zibo, Doroudi, Shayan, Lee, Yae Lim, Izatt, Gregory, Wittman, Sarah, Srinivas, Niranjan, Woods, Damien, Winfree, Erik, Qian, Lulu

“…Two critical challenges in the design and synthesis of molecular robots are modularity and algorithm simplicity. We demonstrate three modular building blocks…”
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Development and initial validation of the addressing client needs with social determinants of health scale (ACN: SDH) by Johnson, Kaprea F

“…The purpose of this study was to validate a scale that can be used by healthcare service professionals, healthcare systems, educators, and researchers to…”
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Histone H4 lysine 16 acetylation regulates cellular lifespan by Dang, Weiwei, Steffen, Kristan K, Perry, Rocco, Dorsey, Jean A, Johnson, F. Brad, Shilatifard, Ali, Kaeberlein, Matt, Kennedy, Brian K, Berger, Shelley L

“…Cells undergoing developmental processes are characterized by persistent non-genetic alterations in chromatin, termed epigenetic changes, represented by…”
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Hidden resilience and adaptive dynamics of the global online hate ecology by Johnson, N. F., Leahy, R., Restrepo, N. Johnson, Velasquez, N., Zheng, M., Manrique, P., Devkota, P., Wuchty, S.

“…Online hate and extremist narratives have been linked to abhorrent real-world events, including a current surge in hate crimes 1 – 6 and an alarming increase…”
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Exploring the participation of young citizen scientists in scientific research: The case of iNaturalist by Aristeidou, Maria, Herodotou, Christothea, Ballard, Heidi L, Young, Alison N, Miller, Annie E, Higgins, Lila, Johnson, Rebecca F

“…Online citizen science projects have broadened options for accessing science and enabled different forms of participation in scientific research for adult and…”
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Patient Preferences in Regulatory Benefit-Risk Assessments: A US Perspective by Johnson, F. Reed, PhD, Zhou, Mo, MA

“…Abstract Demands for greater transparency in US regulatory assessments of benefits and risks, together with growing interest in engaging patients in Food and…”
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Aging alters bone-fat reciprocity by shifting in vivo mesenchymal precursor cell fate towards an adipogenic lineage by Singh, Lakshman, Brennan, Tracy A, Russell, Elizabeth, Kim, Jung-Hoon, Chen, Qijun, Brad Johnson, F, Pignolo, Robert J

“…Abstract Bone marrow derived mesenchymal progenitor cells (MPCs) play an important role in bone homeostasis. Age-related changes occur in bone resulting in a…”
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Fundamentals of G-quadruplex biology by Johnson, F Brad

“…Several decades elapsed between the first descriptions of G-quadruplex nucleic acid structures (G4s) assembled and the emergence of experimental findings…”
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