Search Results - "Johnson, Emma R."

A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors by Menon, Malini, Elliott, Richard, Bowers, Leandra, Balan, Nicolae, Rafiq, Rumana, Costa-Cabral, Sara, Munkonge, Felix, Trinidade, Ines, Porter, Roderick, Campbell, Andrew D., Johnson, Emma R., Esdar, Christina, Buchstaller, Hans-Peter, Leuthner, Birgitta, Rohdich, Felix, Schneider, Richard, Sansom, Owen, Wienke, Dirk, Ashworth, Alan, Lord, Christopher J.

“…Inhibition of the PARP superfamily tankyrase enzymes suppresses Wnt/β-catenin signalling in tumour cells. Here, we describe here a novel, drug-like small…”
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The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer by Najumudeen, Arafath K., Ceteci, Fatih, Fey, Sigrid K., Hamm, Gregory, Steven, Rory T., Hall, Holly, Nikula, Chelsea J., Dexter, Alex, Murta, Teresa, Race, Alan M., Sumpton, David, Vlahov, Nikola, Gay, David M., Knight, John R. P., Jackstadt, Rene, Leach, Joshua D. G., Ridgway, Rachel A., Johnson, Emma R., Nixon, Colin, Hedley, Ann, Gilroy, Kathryn, Clark, William, Malla, Sudhir B., Dunne, Philip D., Rodriguez-Blanco, Giovanny, Critchlow, Susan E., Mrowinska, Agata, Malviya, Gaurav, Solovyev, Dmitry, Brown, Gavin, Lewis, David Y., Mackay, Gillian M., Strathdee, Douglas, Tardito, Saverio, Gottlieb, Eyal, Takats, Zoltan, Barry, Simon T., Goodwin, Richard J. A., Bunch, Josephine, Bushell, Martin, Campbell, Andrew D., Sansom, Owen J.

“…Oncogenic KRAS mutations and inactivation of the APC tumor suppressor co-occur in colorectal cancer (CRC). Despite efforts to target mutant KRAS directly, most…”
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The influence of environmental factors on pond activity of aquatic red-spotted newts Notophthalmus viridescens by Johnson, Emma R., Bowerman, Brielle L., Thomas, Meagan A., Thompson, Lily M., Grayson, Kristine L.

“…Many important components of animal behavior, growth, and reproduction are tightly linked to environmental conditions, particularly for ectothermic freshwater…”
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