Search Results - "Johnson, EB"
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Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice
Published in Journal of neuroinflammation (27-02-2012)“…Recent in vivo and in vitro studies in non-neuronal and neuronal tissues have shown that different pathways of macrophage activation result in cells with…”
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Phytoestrogen supplementation and endometrial cancer
Published in Obstetrics and gynecology (New York. 1953) (01-11-2001)“…BACKGROUND: Phytoestrogens are increasingly used by patients as “natural” alternatives to hormone replacement. Attention in scientific and lay literature has…”
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Biological and clinical manifestations of Huntington’s disease in gene carriers very far from predicted onset
Published in Journal of neurology, neurosurgery and psychiatry (01-06-2022)“…IntroductionCrucial to the future success of treatments in Huntington’s disease is identifying a timepoint where there is a measurable biomarker of early…”
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Lrp4 modulates extracellular integration of cell signaling pathways in development
Published in PloS one (31-12-2008)“…The extent to which cell signaling is integrated outside the cell is not currently appreciated. We show that a member of the low-density receptor-related…”
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Gene therapy strategies for the treatment of spinal cord injury
Published in Therapeutic delivery (01-05-2014)“…Spinal cord injury is a complex pathology often resulting in functional impairment and paralysis. Gene therapy has emerged as a possible solution to the…”
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Increased risk of adverse pregnancy outcome among Somali immigrants in Washington state
Published in American journal of obstetrics and gynecology (01-08-2005)“…The purpose of this study was to compare maternal and neonatal morbidity among Somali immigrants, US-born blacks and whites in Washington state. Washington…”
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Abnormal development of the apical ectodermal ridge and polysyndactyly in Megf7-deficient mice
Published in Human molecular genetics (15-11-2005)“…Megf7/Lrp4 is a member of the functionally diverse low-density lipoprotein receptor gene family, a class of ancient and highly conserved cell surface receptors…”
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Transplantation of mesenchymal stem cells promotes an alternative pathway of macrophage activation and functional recovery after spinal cord injury
Published in Journal of neurotrauma (20-05-2012)“…Mesenchymal stem cells (MSC) derived from bone marrow can potentially reduce the acute inflammatory response in spinal cord injury (SCI) and thus promote…”
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Does size matter? Tumor size and morphology as predictors of nodal status and recurrence in endometrial cancer
Published in Gynecologic oncology (01-12-2005)“…To determine whether tumor size or morphology is predictive of extrauterine disease and/or recurrence risk in endometrial cancer and therefore guide decisions…”
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Early Transplantation of Mesenchymal Stem Cells After Spinal Cord Injury Relieves Pain Hypersensitivity Through Suppression of Pain‐Related Signaling Cascades and Reduced Inflammatory Cell Recruitment
Published in Stem cells (Dayton, Ohio) (01-06-2015)“…Bone marrow‐derived mesenchymal stem cells (BMSC) modulate inflammatory/immune responses and promote motor functional recovery after spinal cord injury (SCI)…”
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Immunological Characterization and Therapeutic Activity of an Altered-Peptide Ligand, NBI-6024, Based on the Immunodominant Type 1 Diabetes Autoantigen Insulin B-Chain (9–23) Peptide
Published in Diabetes (New York, N.Y.) (01-07-2002)“…Immunological Characterization and Therapeutic Activity of an Altered-Peptide Ligand, NBI-6024, Based on the Immunodominant Type 1 Diabetes Autoantigen Insulin…”
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Methamphetamine abuse and rhabdomyolysis in the ED: A 5-year study
Published in The American journal of emergency medicine (01-11-1999)“…Patients with methamphetamine toxicity are presenting in greater numbers each year to emergency departments (ED) in the US. These patients are frequently…”
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Bone marrow-derived mesenchymal stem cells become antiangiogenic when chondrogenically or osteogenically differentiated: implications for bone and cartilage tissue engineering
Published in Tissue engineering. Part A (01-01-2014)“…Osteochondral tissue repair requires formation of vascularized bone and avascular cartilage. Mesenchymal stem cells stimulate angiogenesis both in vitro and in…”
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Cutting Edge: Diabetes-Associated Quantitative Trait Locus, Idd4, Is Responsible for the IL-12p40 Overexpression Defect in Nonobese Diabetic (NOD) Mice
Published in The Journal of immunology (1950) (01-10-2003)“…Abstract APCs of the nonobese diabetic (NOD) mouse have a genetically programmed capacity to overexpress IL-12p40, a cytokine critical for development of…”
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The influence of serum, glucose and oxygen on intervertebral disc cell growth in vitro: implications for degenerative disc disease
Published in Arthritis research & therapy (01-01-2008)“…The avascular nature of the human intervertebral disc (IVD) is thought to play a major role in disc pathophysiology by limiting nutrient supply to resident IVD…”
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SJL and NOD macrophages are uniquely characterized by genetically programmed, elevated expression of the IL-12(p40) gene, suggesting a conserved pathway for the induction of organ-specific autoimmunity
Published in Journal of leukocyte biology (01-03-2001)“…Genetic susceptibility of the SJL mouse to experimental autoimmune encephalomyelitis (EAE) appears, in part, to be a result of genes that promote abnormal…”
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An In Vitro Comparison of the Incorporation, Growth, and Chondrogenic Potential of Human Bone Marrow versus Adipose Tissue Mesenchymal Stem Cells in Clinically Relevant Cell Scaffolds Used for Cartilage Repair
Published in Cartilage (01-10-2015)“…Aim To compare the incorporation, growth, and chondrogenic potential of bone marrow (BM) and adipose tissue (AT) mesenchymal stem cells (MSCs) in scaffolds…”
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Unrecognized malfunction in computerized patient simulators
Published in British journal of anaesthesia : BJA (01-12-2004)Get full text
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Methamphetamine abuse and emergency department utilization
Published in The Western journal of medicine (01-04-1999)“…Methamphetamine (MAP) abuse continues to increase worldwide, based on morbidity, mortality, drug treatment, and epidemiologic studies and surveys. MAP abuse…”
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