Search Results - "Johnson, Craig N."

Repeated stress to the skin amplifies neutrophil infiltration in a keratin 17- and PKCα-dependent manner by Xu, Yang, Cohen, Erez, Johnson, Craig N, Parent, Carole A, Coulombe, Pierre A

“…Neutrophils are the first immune cells to reach inflamed sites and contribute to the pathogenesis of chronic inflammatory skin diseases. Yet, little is known…”
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TGF-β1 activates neutrophil signaling and gene expression but not migration by Hein, Lauren E., SenGupta, Shuvasree, Gunasekaran, Gaurie, Johnson, Craig N., Parent, Carole A.

“…Tumor-associated neutrophils are found in many types of cancer and are often reported to contribute to negative outcomes. The presence of transforming growth…”
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Multiple roles for the non-coding RNA SRA in regulation of adipogenesis and insulin sensitivity by Xu, Bin, Gerin, Isabelle, Miao, Hongzhi, Vu-Phan, Dang, Johnson, Craig N, Xu, Ruichuan, Chen, Xiao-Wei, Cawthorn, William P, MacDougald, Ormond A, Koenig, Ronald J

“…Peroxisome proliferator-activated receptor-γ (PPARγ) is a master transcriptional regulator of adipogenesis. Hence, the identification of PPARγ coactivators…”
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Pax2 and Pax8 Proteins Regulate Urea Transporters and Aquaporins to Control Urine Concentration in the Adult Kidney by Laszczyk, Ann M, Higashi, Atsuko Y, Patel, Sanjeevkumar R, Johnson, Craig N, Soofi, Abdul, Abraham, Saji, Dressler, Gregory R

“…As the glomerular filtrate passes through the nephron and into the renal medulla, electrolytes, water, and urea are reabsorbed through the concerted actions of…”
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The injured sciatic nerve atlas (iSNAT), insights into the cellular and molecular basis of neural tissue degeneration and regeneration by Zhao, Xiao-Feng, Huffman, Lucas D, Hafner, Hannah, Athaiya, Mitre, Finneran, Matthew C, Kalinski, Ashley L, Kohen, Rafi, Flynn, Corey, Passino, Ryan, Johnson, Craig N, Kohrman, David, Kawaguchi, Riki, Yang, Lynda J S, Twiss, Jeffery L, Geschwind, Daniel H, Corfas, Gabriel, Giger, Roman J

“…Upon trauma, the adult murine peripheral nervous system (PNS) displays a remarkable degree of spontaneous anatomical and functional regeneration. To explore…”
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Neutrophil-inflicted vasculature damage suppresses immune-mediated optic nerve regeneration by Passino, Ryan, Finneran, Matthew C., Hafner, Hannah, Feng, Qian, Huffman, Lucas D., Zhao, Xiao-Feng, Johnson, Craig N., Kawaguchi, Riki, Oses-Prieto, Juan A., Burlingame, Alma L., Geschwind, Daniel H., Benowitz, Larry I., Giger, Roman J.

“…In adult mammals, injured retinal ganglion cells (RGCs) fail to spontaneously regrow severed axons, resulting in permanent visual deficits. Robust axon growth,…”
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The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages by Carson, 4th, William F, Cavassani, Karen A, Soares, Elyara M, Hirai, Soichiro, Kittan, Nicolai A, Schaller, Matthew A, Scola, Melissa M, Joshi, Amrita, Matsukawa, Akihiro, Aronoff, David M, Johnson, Craig N, Dou, Yali, Gallagher, Katherine A, Kunkel, Steven L

“…Macrophages are critical immune cells for the clearance of microbial pathogens and cellular debris from peripheral tissues. Macrophage inflammatory responses…”
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Distinct Gene Expression Profiles of Viral- and Nonviral-Associated Merkel Cell Carcinoma Revealed by Transcriptome Analysis by Harms, Paul W., Patel, Rajiv M., Verhaegen, Monique E., Giordano, Thomas J., Nash, Kevin T., Johnson, Craig N., Daignault, Stephanie, Thomas, Dafydd G., Gudjonsson, Johann E., Elder, James T., Dlugosz, Andrzej A., Johnson, Timothy M., Fullen, Douglas R., Bichakjian, Christopher K.

“…Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine tumor with high mortality rates. Merkel cell polyomavirus (MCPyV), identified in the…”
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Human-Induced Pluripotent Stem Cell (iPSC)-Derived GABAergic Neuron Differentiation in Bipolar Disorder by Schill, Daniel J, Attili, Durga, DeLong, Cynthia J, McInnis, Melvin G, Johnson, Craig N, Murphy, Geoffrey G, O'Shea, K Sue

“…Bipolar disorder (BP) is a recurring psychiatric condition characterized by alternating episodes of low energy (depressions) followed by manias (high energy)…”
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Significance of stress keratin expression in normal and diseased epithelia by Cohen, Erez, Johnson, Craig N., Wasikowski, Rachael, Billi, Allison C., Tsoi, Lam C., Kahlenberg, J. Michelle, Gudjonsson, Johann E., Coulombe, Pierre A.

“…A group of keratin intermediate filament genes, the type II KRT6A-C and type I KRT16 and KRT17, are deemed stress responsive as they are induced in…”
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A novel intergenic ETnII-β insertion mutation causes multiple malformations in polypodia mice by Lehoczky, Jessica A, Thomas, Peedikayil E, Patrie, Kevin M, Owens, Kailey M, Villarreal, Lisa M, Galbraith, Kenneth, Washburn, Joe, Johnson, Craig N, Gavino, Bryant, Borowsky, Alexander D, Millen, Kathleen J, Wakenight, Paul, Law, William, Van Keuren, Margaret L, Gavrilina, Galina, Hughes, Elizabeth D, Saunders, Thomas L, Brihn, Lesil, Nadeau, Joseph H, Innis, Jeffrey W

“…Mouse early transposon insertions are responsible for ~10% of spontaneous mutant phenotypes. We previously reported the phenotypes and genetic mapping of…”
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Modulation of Brain Transcriptome by Combined Histone Deacetylase Inhibition and Plasma Treatment Following Traumatic Brain Injury and Hemorrhagic Shock by Dekker, Simone E., Biesterveld, Ben E., Bambakidis, Ted, Williams, Aaron M., Tagett, Rebecca, Johnson, Craig N., Sillesen, Martin, Liu, Baoling, Li, Yongqing, Alam, Hasan B.

“…We previously showed that the addition of valproic acid (VPA), a histone deacetylase inhibitor, to fresh frozen plasma (FFP) resuscitation attenuates brain…”
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Resuscitation with Valproic Acid Alters Inflammatory Genes in a Porcine Model of Combined Traumatic Brain Injury and Hemorrhagic Shock by Bambakidis, Ted, Dekker, Simone E, Sillesen, Martin, Liu, Baoling, Johnson, Craig N, Jin, Guang, de Vries, Helga E, Li, Yongqing, Alam, Hasan B

“…Traumatic brain injury and hemorrhagic shock (TBI+HS) elicit a complex inflammatory response that contributes to secondary brain injury. There is currently no…”
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Effect of pharmacologic resuscitation on the brain gene expression profiles in a swine model of traumatic brain injury and hemorrhage by Dekker, Simone E, Bambakidis, Ted, Sillesen, Martin, Liu, Baoling, Johnson, Craig N, Jin, Guang, Li, Yongqing, Alam, Hasan B

“…We have previously shown that addition of valproic acid (VPA; a histone deacetylase inhibitor) to hetastarch (Hextend [HEX]) resuscitation significantly…”
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Induction of p53 suppresses chronic myeloid leukemia by Peterson, Luke F., Lo, Miao-Chia, Liu, Yihong, Giannola, Diane, Mitrikeska, Emilija, Donato, Nicholas J., Johnson, Craig N., Wang, Shaomeng, Mercer, Jessica, Talpaz, Moshe

“…Chronic myeloid leukemia (CML) is characterized by the chromosomal translocation 9;22, known as the Philadelphia chromosome (Ph), which produces the BCR-ABL…”
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Targeting p53 in CML Chronic Phase Leukemia Stem Cells by Peterson, Luke F, Lo, Miao-Chia, Lui, Yihong, Gianolla, Diane, Mitrikeska, Emilija, Donato, Nicholas J, Johnson, Craig N, Wang, Shaomeng, Mercer, Jessica, Talpaz, Moshe

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Repeated stress to the skin amplifies neutrophil infiltration in a keratin 17- and PKC[alpha]-dependent manner by Xu, Yang, Cohen, Erez, Johnson, Craig N, Parent, Carole A, Coulombe, Pierre A

“…Neutrophils are the first immune cells to reach inflamed sites and contribute to the pathogenesis of chronic inflammatory skin diseases. Yet, little is known…”
Get full text

TGF-[beta]1 activates neutrophil signaling and gene expression but not migration by Hein, Lauren E, SenGupta, Shuvasree, Gunasekaran, Gaurie, Johnson, Craig N, Parent, Carole A

“…Tumor-associated neutrophils are found in many types of cancer and are often reported to contribute to negative outcomes. The presence of transforming growth…”
Get full text

Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks by Evelyn, Chris R, Lisabeth, Erika M, Wade, Susan M, Haak, Andrew J, Johnson, Craig N, Lawlor, Elizabeth R, Neubig, Richard R

“…Metastasis is the major cause of cancer deaths and control of gene transcription has emerged as a critical contributing factor. RhoA- and RhoC-induced gene…”
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A Novel Intergenic ETnII-[beta] Insertion Mutation Causes Multiple Malformations in Polypodia Mice: e1003967 by Lehoczky, Jessica A, Thomas, Peedikayil E, Patrie, Kevin M, Owens, Kailey M, Villarreal, Lisa M, Galbraith, Kenneth, Washburn, Joe, Johnson, Craig N, Gavino, Bryant, Borowsky, Alexander D, Millen, Kathleen J, Wakenight, Paul, Law, William, Keuren, Margaret LVan, Gavrilina, Galina, Hughes, Elizabeth D, Saunders, Thomas L, Brihn, Lesil, Nadeau, Joseph H, Innis, Jeffrey W

“…Mouse early transposon insertions are responsible for ~10% of spontaneous mutant phenotypes. We previously reported the phenotypes and genetic mapping of…”
Get full text