Search Results - "Johnson, Barry"

Reliability Theory and Practice for Unmanned Aerial Vehicles by Xing, Liudong, Johnson, Barry W.

“…Due to rapid advancements on the Internet of Things (IoT), unmanned aerial vehicles (UAVs), also known as drones, are transforming numerous military and civil…”
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Call Bell Usage: Tracking the Effect of Hourly Staff Rounding by Johnson, Barry C, Bryant, Laurie

“…Hourly rounding by nursing staff helps to proactively manage patient needs and minimize the number of unscheduled calls from patients. The focus of this study…”
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Mission Reliability, Cost and Time for Cold Standby Computing Systems with Periodic Backup by Levitin, Gregory, Xing, Liudong, Johnson, Barry W., Dai, Yuanshun

“…Life critical applications like space missions and flight controls require their computing systems to be equipped with some fault-tolerance mechanism to meet…”
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The National Science Foundation: Innovation Through Partnerships by Johnson, Barry W.

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A Homology Model of HIV-1 Integrase and Analysis of Mutations Designed to Test the Model by Johnson, Barry C., Métifiot, Mathieu, Ferris, Andrea, Pommier, Yves, Hughes, Stephen H.

“…Although there are structures of the different domains of human immunodeficiency virus type 1 (HIV-1) integrase (IN), there is no structure of the entire…”
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ROADMAPS: An Online Database of Response Data, Dosing Regimens, and Toxicities of Approved Oncology Drugs as Single Agents to Guide Preclinical In Vivo Studies by Hollingshead, Melinda G, Greenberg, Nathaniel, Gottholm-Ahalt, Michelle, Camalier, Richard, Johnson, Barry C, Collins, Jerry M, Doroshow, James H

“…Preclinical studies provide valuable data in the early development of novel drugs for patients with cancer. Many cancer treatment regimens now utilize multiple…”
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5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives as Potent HIV-1-Integrase-Allosteric-Site Inhibitors by Peese, Kevin M, Allard, Christopher W, Connolly, Timothy, Johnson, Barry L, Li, Chen, Patel, Manoj, Sorensen, Margaret E, Walker, Michael A, Meanwell, Nicholas A, McAuliffe, Brian, Minassian, Beatrice, Krystal, Mark, Parker, Dawn D, Lewis, Hal A, Kish, Kevin, Zhang, Ping, Nolte, Robert T, Simmermacher, Jean, Jenkins, Susan, Cianci, Christopher, Naidu, B. Narasimhulu

“…A series of 5,6,7,8-tetrahydro-1,6-naphthyridine derivatives targeting the allosteric lens-epithelium-derived-growth-factor-p75 (LEDGF/p75)-binding site on…”
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Molecular Dynamics Approaches Estimate the Binding Energy of HIV-1 Integrase Inhibitors and Correlate with In Vitro Activity by JOHNSON, Barry C, METIFIOT, Mathieu, POMMIER, Yves, HUGHES, Stephen H

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Bicyclic 1‑Hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide-Containing HIV‑1 Integrase Inhibitors Having High Antiviral Potency against Cells Harboring Raltegravir-Resistant Integrase Mutants by Zhao, Xue Zhi, Smith, Steven J, Métifiot, Mathieu, Johnson, Barry C, Marchand, Christophe, Pommier, Yves, Hughes, Stephen H, Burke, Terrence R

“…Integrase (IN) inhibitors are the newest class of antiretroviral agents developed for the treatment of HIV-1 infections. Merck’s Raltegravir (RAL) (October…”
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Isoform- and Phosphorylation-specific Multiplexed Quantitative Pharmacodynamics of Drugs Targeting PI3K and MAPK Signaling in Xenograft Models and Clinical Biopsies by Herrick, William G, Kilpatrick, Casey L, Hollingshead, Melinda G, Esposito, Dominic, O'Sullivan Coyne, Geraldine, Gross, Andrea M, Johnson, Barry C, Chen, Alice P, Widemann, Brigitte C, Doroshow, James H, Parchment, Ralph E, Srivastava, Apurva K

“…Ras/Raf/MEK/ERK (MAPK) and PI3K/AKT signaling pathways influence several cell functions involved in oncogenesis, making them attractive drug targets. We…”
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Selectivity for strand-transfer over 3'-processing and susceptibility to clinical resistance of HIV-1 integrase inhibitors are driven by key enzyme-DNA interactions in the active site by Métifiot, Mathieu, Johnson, Barry C, Kiselev, Evgeny, Marler, Laura, Zhao, Xue Zhi, Burke, Jr, Terrence R, Marchand, Christophe, Hughes, Stephen H, Pommier, Yves

“…Integrase strand transfer inhibitors (INSTIs) are highly effective against HIV infections. Co-crystal structures of the prototype foamy virus intasome have…”
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Combination therapy with pazopanib and tivantinib modulates VEGF and c-MET levels in refractory advanced solid tumors by Kummar, Shivaani, Srivastava, Apurva K., Navas, Tony, Cecchi, Fabiola, Lee, Young H., Bottaro, Donald P., Park, Sook Ryun, Do, Khanh T., Jeong, Woondong, Johnson, Barry C., Voth, Andrea R., Rubinstein, Larry, Wright, John J., Parchment, Ralph E., Doroshow, James H., Chen, Alice P.

“…Summary The vascular endothelial growth factor (VEGF)/VEGFR and hepatocyte growth factor (HGF)/c-MET signaling pathways act synergistically to promote…”
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A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants by Johnson, Barry C, Pauly, Gary T, Rai, Ganesha, Patel, Disha, Bauman, Joseph D, Baker, Heather L, Das, Kalyan, Schneider, Joel P, Maloney, David J, Arnold, Eddy, Thomas, Craig J, Hughes, Stephen H

“…The recently approved anti-AIDS drug rilpivirine (TMC278, Edurant) is a nonnucleoside inhibitor (NNRTI) that binds to reverse transcriptase (RT) and…”
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Will Testing of Chemicals for Safety Assessment and Management Finally Become a Reality in the U.S.? Some Good News? Maybe by Johnson, Barry L.

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Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors by Takebe, Naoko, Coyne, Geraldine O'Sullivan, Kummar, Shivaani, Collins, Jerry, Reid, Joel M, Piekarz, Richard, Moore, Nancy, Juwara, Lamin, Johnson, Barry C, Bishop, Rachel, Lin, Frank I, Mena, Esther, Choyke, Peter L, Lindenberg, M Liza, Rubinstein, Larry V, Bonilla, Cecilia Monge, Goetz, Matthew P, Ames, Matthew M, McGovern, Renee M, Streicher, Howard, Covey, Joseph M, Doroshow, James H, Chen, Alice P

“…Differential responses to tamoxifen may be due to inter-patient variability in tamoxifen metabolism into pharmacologically active Z-endoxifen. Z-endoxifen…”
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Lens Design Fundamentals (2nd Edition) by Kingslake, Rudolf, Johnson, R. Barry

“…This book provides the skills and knowledge to move into the exciting world of contemporary lens design and develop practical lenses needed for the great…”
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MK-0536 Inhibits HIV-1 Integrases Resistant to Raltegravir by METIFIOT, Mathieu, JOHNSON, Barry, SMITH, Steven, XUE ZHI ZHAO, MARCHAND, Christophe, BURKE, Terrence, HUGHES, Stephen, POMMIER, Yves

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Lens Design Fundamentals, 2nd Edition by Kingslake, Rudolf, Johnson, R. Barry

“…Thoroughly revised and expanded to reflect the substantial changes in the field since its publication in 1978Strong emphasis on how to effectively use software…”
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Mutagenesis of Human Immunodeficiency Virus Reverse Transcriptase p51 Subunit Defines Residues Contributing to Vinylogous Urea Inhibition of Ribonuclease H Activity by Chung, Suhman, Miller, Jennifer T., Johnson, Barry C., Hughes, Stephen H., Le Grice, Stuart F.J.

“…The vinylogous urea, NSC727447, was proposed to allosterically inhibit ribonuclease H (RNase H) activity of human immunodeficiency virus type 1 reverse…”
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Regulation of cell movement is mediated by stretch-activated calcium channels by Lee, Juliet, Ishihara, Akira, Oxford, Gerry, Johnson, Barry, Jacobson, Ken

“…Intracellular calcium regulates many of the molecular processes that are essential for cell movement. It is required for the production of actomyosin-based…”
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