Search Results - "Johnson, Alfred C."

The Transcription Factor GCF2 Is an Upstream Repressor of the Small GTPAse RhoA, Regulating Membrane Protein Trafficking, Sensitivity to Doxorubicin, and Resistance to Cisplatin by Shen, Ding-Wu, Pouliot, Lynn M, Gillet, Jean-Pierre, Ma, Wenting, Johnson, Alfred C, Hall, Matthew D, Gottesman, Michael M

“…Our aim was to explore the involvement of the transcriptional suppressor GCF2 in silencing RhoA, disorganization of the cytoskeleton, mislocalization of MRP1,…”
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The US National Institutes of Health approach to inclusive excellence by Bernard, Marie A., Johnson, Alfred C., Hopkins-Laboy, Treava, Tabak, Lawrence A.

“…The National Institutes of Health (NIH) is committed to increasing the participation of underrepresented groups in science and medicine, through changes in our…”
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Affirming NIH’s commitment to addressing structural racism in the biomedical research enterprise by Collins, Francis S., Adams, Amy Bany, Aklin, Courtney, Archer, Trevor K., Bernard, Marie A., Boone, Ericka, Burklow, John, Evans, Michele K., Jackson, Sadhana, Johnson, Alfred C., Lorsch, Jon, Lowden, Mia Rochelle, Nápoles, Anna María, Ordóñez, Anna E., Rivers, Robert, Rucker, Victoria, Schwetz, Tara, Segre, Julia A., Tabak, Lawrence A., Hooper, Monica Webb, Wolinetz, Carrie

“…NIH has acknowledged and committed to ending structural racism. The framework for NIH’s approach, summarized here, includes understanding barriers; developing…”
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Transactivation of the EGFR by AP-1 is induced by Helicobacter pylori in gastric cancer by ASHKTORAB, Hassan, DAREMIPOURAN, Mohammad, WILSON, Melissa, SIDDIQI, Serwat, LEE, Edward L, RAKHSHANI, Nasser, MALEKZADEH, Reza, JOHNSON, Alfred C, HEWITT, Stephen M, SMOOT, Duane T

“…Helicobacter pylori infection of the gastric mucosa is strongly associated with gastritis, peptic ulcer disease, and gastric cancer. However, the mechanisms by…”
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The Imperative to Reimagine Assisted Living by Zimmerman, Sheryl, Carder, Paula, Schwartz, Lindsay, Silbersack, Johanna, Temkin-Greener, Helena, Thomas, Kali S., Ward, Kimberly, Jenkens, Robert, Jensen, Liz, Johnson, Alfred C., Johnson, Jed, Johnston, Tim, Kaes, Loretta, Katz, Paul, Klinger, Juliet Holt, Lieblich, Cathy, Mace, Beth, O'Neil, Kevin, Pace, Douglas D., Scales, Kezia, Stone, Robyn I., Thomas, Sarah, Williams, Paul J., Williams, Keren Brown

“…Assisted living (AL) has existed in the United States for decades, evolving in response to older adults’ need for supportive care and distaste for nursing…”
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GC‐binding factor 2 interacts with dishevelled and regulates Wnt signaling pathways in human carcinoma cell lines by Ohtsuka, Hideo, Oikawa, Masaya, Ariake, Kyohei, Rikiyama, Toshiki, Motoi, Fuyuhiko, Katayose, Yu, Unno, Michiaki, Johnson, Alfred C.

“…GC‐binding factor 2 (GCF2), a transcriptional repressor that decreases the activity of several genes is capable of binding directly to the GC‐rich sequence of…”
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GC Factor 2 Represses Platelet-Derived Growth Factor A-Chain Gene Transcription and Is Itself Induced by Arterial Injury by Khachigian, Levon M, Santiago, Fernando S, Rafty, Louise A, Chan, Onza L.-W, Delbridge, Gabrielle J, Bobik, Alex, Collins, Tucker, Johnson, Alfred C

“…Platelet-derived growth factor (PDGF) is a mitogen and chemoattractant for a wide variety of cell types. The genes encoding PDGF A chain (PDGF-A) and PDGF B…”
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Early growth response-1 gene mediates up-regulation of epidermal growth factor receptor expression during hypoxia by NISHI, Hirotaka, NISHI, Katsura H, JOHNSON, Alfred C

“…Hypoxia occurs during development of cancers and is correlated with cancer progression. Hypoxia also induces epidermal growth factor receptor (EGFR)…”
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Leucine-rich repeat (in Flightless I) interacting protein-1 regulates a rapid type I interferon response by Bagashev, Asen, Fitzgerald, Michael C, Larosa, David F, Rose, Patrick P, Cherry, Sara, Johnson, Alfred C, Sullivan, Kathleen E

“…The cell autonomous response to viral infection is carefully regulated to induce type I interferons (IFNs), which in turn induce the establishment of an…”
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GCF2: expression and molecular analysis of repression by Rikiyama, Toshiki, Curtis, Joseph, Oikawa, Masaya, Zimonjic, Drazen B, Popescu, Nicholas, Murphy, Barbara A, Wilson, Melissa A, Johnson, Alfred C

“…GC-binding factor 2 (GCF2) is a transcriptional repressor that decreases activity of the epidermal growth factor receptor (EGFR) and other genes. We have…”
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An upstream repressor element plays a role in Igf2 imprinting by Eden, Sharon, Constancia, Miguel, Hashimshony, Tamar, Dean, Wendy, Goldstein, Beth, Johnson, Alfred C., Keshet, Ilana, Reik, Wolf, Cedar, Howard

“…The imprinted Igf2 gene is associated with a small upstream region that is differentially methylated on the active paternal allele. We have identified a…”
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p53 Homologue p63 Represses Epidermal Growth Factor Receptor Expression by Nishi, Hirotaka, Senoo, Makoto, Nishi, Katsura H., Murphy, Barbara, Rikiyama, Toshiki, Matsumura, Yasuko, Habu, Sonoko, Johnson, Alfred C.

“…Tumor suppressor p53 has been shown to transactivate epidermal growth factor receptor (EGFR) expression through binding to a putative p53 responsive element in…”
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Activation of Epidermal Growth Factor Receptor Gene Transcription by Phorbol 12-Myristate 13-Acetate Is Mediated by Activator Protein 2 (∗) by Johnson, Alfred C.

“…The response of the epidermal growth factor (EGF) receptor gene to phorbol 12-myristate 13-acetate (PMA) was analyzed using nuclei and nuclear extracts…”
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The United States National Institutes of Health approach to inclusive excellence by Bernard, Marie A., Johnson, Alfred C., Hopkins-Laboy, Treava, Tabak, Lawrence A.

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Analysis of the epidermal growth factor receptor promoter: the effect of nuclear factor-kappaB by Nishi, Hirotaka, Neta, Gila, Nishi, Katsura H, Akers, Latania M, Rikiyama, Toshiki, Proctor, Kimberle N, Murphy, Barbara A, Johnson, Alfred C

“…The epidermal growth factor receptor gene is highly regulated and responsive to extracellular stimuli that control cell growth. We have identified five…”
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Molecular Cloning and Characterization of a Transcription Regulator with Homology to GC-binding Factor by Reed, Andre L., Yamazaki, Hitoshi, Kaufman, Joshua D., Rubinstein, Yaffa, Murphy, Barbara, Johnson, Alfred C.

“…GC-binding factor (GCF) represses transcription of certain genes and is encoded by a 3.0-kilobase mRNA (Kageyama, R., and Pastan, I. (1989) Cell 59, 815–825)…”
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The Wilms' Tumor Gene Product WT1 Mediates the Down-regulation of the Rat Epidermal Growth Factor Receptor by Nerve Growth Factor in PC12 Cells by Liu, Xu-Wen, Gong, Li-Jie, Guo, Li-Ying, Katagiri, Yasuhiro, Jiang, Hao, Wang, Zhao-Yi, Johnson, Alfred C., Guroff, Gordon

“…Recently, we characterized the rat epidermal growth factor receptor (EGFR) promoter and demonstrated that TCC repeat sequences are required for the…”
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Transcriptional Down-regulation of Epidermal Growth Factor Receptors by Nerve Growth Factor Treatment of PC12 Cells by Shibutani, M, Lazarovici, P, Johnson, A C, Katagiri, Y, Guroff, G

“…Treatment of PC12 cells with nerve growth factor leads to a decrease in the number of epidermal growth factor receptors on the cell membrane. The mRNA for the…”
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Identification of an additional p53-responsive site in the human epidermal growth factor receptor gene promotor by SAEED SHEIKH, M, CARRIER, F, JOHNSON, A. C, OGDON, S. E, FORNACE, A. J

“…Exogenously introduced wild-type and mutant p53 have recently been reported to enhance the human epidermal growth factor receptor (EGF-R) gene promoter…”
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Interferon regulatory factor-1 is a major regulator of epidermal growth factor receptor gene expression by Rubinstein, Yaffa R, Proctor, Kimberle N, Bergel, Michael, Murphy, Barbara, Johnson, Alfred C

“…Overexpression of the epidermal growth factor receptor (EGFR) occurs in many tumors and in breast cancer correlates with poor prognosis for treatment. Here, we…”
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