Search Results - "Johnson, Alex"

Bacterial gasdermins reveal an ancient mechanism of cell death by Johnson, Alex G, Wein, Tanita, Mayer, Megan L, Duncan-Lowey, Brianna, Yirmiya, Erez, Oppenheimer-Shaanan, Yaara, Amitai, Gil, Sorek, Rotem, Kranzusch, Philip J

“…Gasdermin proteins form large membrane pores in human cells that release immune cytokines and induce lytic cell death. Gasdermin pore formation is triggered by…”
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Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation by Lapointe, Christopher P., Grosely, Rosslyn, Johnson, Alex G., Wang, Jinfan, Fernández, Israel S., Puglisi, Joseph D.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a beta-CoV that recently emerged as a human pathogen and is the causative agent of the COVID-19…”
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What bacterial cell death teaches us about life by Johnson, Alex G, Kranzusch, Philip J

“…Often this mechanistic division is poorly defined, but like the PCD of multicellular eukaryotes, bacterial Abi employs host-directed mechanisms to fend off…”
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Small RNAs are modified with N-glycans and displayed on the surface of living cells by Flynn, Ryan A., Pedram, Kayvon, Malaker, Stacy A., Batista, Pedro J., Smith, Benjamin A.H., Johnson, Alex G., George, Benson M., Majzoub, Karim, Villalta, Peter W., Carette, Jan E., Bertozzi, Carolyn R.

“…Glycans modify lipids and proteins to mediate inter- and intramolecular interactions across all domains of life. RNA is not thought to be a major target of…”
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Breaking the Ring of Fire: How Ridge Collision, Slab Age, and Convergence Rate Narrowed and Terminated the Antarctic Continental Arc by Burton‐Johnson, Alex, Bastias, Joaquin, Kraus, Stefan

“…The geometry of the Antarctic‐Phoenix Plate system, with the Antarctic Plate forming both the overriding plate and the conjugate to the subducting oceanic…”
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Interpretation and Automatic Generation of Fermi‐Orbital Descriptors by Schwalbe, Sebastian, Trepte, Kai, Fiedler, Lenz, Johnson, Alex I., Kraus, Jakob, Hahn, Torsten, Peralta, Juan E., Jackson, Koblar A., Kortus, Jens

“…We present an interpretation of Fermi‐orbital descriptors (FODs) and argue that these descriptors carry chemical bonding information. We show that a bond order…”
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Air–Water Partitioning of Biomass-Burning Phenols and the Effects of Temperature and Salinity by McFall, Alexander S, Johnson, Alex W, Anastasio, Cort

“…Biomass burning (BB) emits organic gases that, with chemical aging, can form secondary organic aerosol (SOA) in both the gas and aqueous phases. One class of…”
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Giant Enhancement of Defect-Bound Exciton Luminescence and Suppression of Band-Edge Luminescence in Monolayer WSe2–Ag Plasmonic Hybrid Structures by Johnson, Alex D, Cheng, Fei, Tsai, Yutsung, Shih, Chih-Kang

“…We have investigated how the photoluminescence (PL) of WSe2 is modified when coupled to Ag plasmonic structures at low temperature. Chemical vapor deposition…”
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Dynamics of IRES-mediated translation by Johnson, Alex G., Grosely, Rosslyn, Petrov, Alexey N., Puglisi, Joseph D.

“…Viral internal ribosome entry sites (IRESs) are unique RNA elements, which use stable and dynamic RNA structures to recruit ribosomes and drive protein…”
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Microstructure, Fatigue Behavior, and Failure Mechanisms of Direct Laser-Deposited Inconel 718 by Johnson, Alex S., Shao, Shuai, Shamsaei, Nima, Thompson, Scott M., Bian, Linkan

“…Inconel 718 is considered to be a superalloy with a series of superior properties such as high strength, creep resistance, and corrosion resistance at room and…”
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Structural basis of Gabija anti-phage defence and viral immune evasion by Antine, Sadie P., Johnson, Alex G., Mooney, Sarah E., Leavitt, Azita, Mayer, Megan L., Yirmiya, Erez, Amitai, Gil, Sorek, Rotem, Kranzusch, Philip J.

“…Bacteria encode hundreds of diverse defence systems that protect them from viral infection and inhibit phage propagation 1 – 5 . Gabija is one of the most…”
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eIF5B gates the transition from translation initiation to elongation by Wang, Jinfan, Johnson, Alex G., Lapointe, Christopher P., Choi, Junhong, Prabhakar, Arjun, Chen, Dong-Hua, Petrov, Alexey N., Puglisi, Joseph D.

“…Translation initiation determines both the quantity and identity of the protein that is encoded in an mRNA by establishing the reading frame for protein…”
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Global protein turnover quantification in Escherichia coli reveals cytoplasmic recycling under nitrogen limitation by Gupta, Meera, Johnson, Alex N. T., Cruz, Edward R., Costa, Eli J., Guest, Randi L., Li, Sophia Hsin-Jung, Hart, Elizabeth M., Nguyen, Thao, Stadlmeier, Michael, Bratton, Benjamin P., Silhavy, Thomas J., Wingreen, Ned S., Gitai, Zemer, Wühr, Martin

“…Protein turnover is critical for proteostasis, but turnover quantification is challenging, and even in well-studied E. coli , proteome-wide measurements remain…”
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Head-Mounted Display Use in Surgery: A Systematic Review by Rahman, Rafa, Wood, Matthew E., Qian, Long, Price, Carrie L., Johnson, Alex A., Osgood, Greg M.

“…Purpose. We analyzed the literature to determine (1) the surgically relevant applications for which head-mounted display (HMD) use is reported; (2) the types…”
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Laboratory freeze–thaw assessment of cement, fly ash, and fiber stabilized pavement foundation materials by Zhang, Yang, Johnson, Alex E., White, David J.

“…Freeze–thaw cycles in pavement foundation layers can cause rapid accumulation of pavement damage. To reduce the effects of freeze–thaw cycles, there is a need…”
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Cryo-EM structure of the RADAR supramolecular anti-phage defense complex by Duncan-Lowey, Brianna, Tal, Nitzan, Johnson, Alex G., Rawson, Shaun, Mayer, Megan L., Doron, Shany, Millman, Adi, Melamed, Sarah, Fedorenko, Taya, Kacen, Assaf, Brandis, Alexander, Mehlman, Tevie, Amitai, Gil, Sorek, Rotem, Kranzusch, Philip J.

“…RADAR is a two-protein bacterial defense system that was reported to defend against phage by “editing” messenger RNA. Here, we determine cryo-EM structures of…”
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The Dysphagia Handicap Index: Development and Validation by Silbergleit, Alice K., Schultz, Lonni, Jacobson, Barbara H., Beardsley, Tausha, Johnson, Alex F.

“…Quality-of-life indicators for dysphagia provide invaluable information to the treating clinician regarding the success or failure of swallowing therapy. The…”
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Structure and assembly of a bacterial gasdermin pore by Johnson, Alex G., Mayer, Megan L., Schaefer, Stefan L., McNamara-Bordewick, Nora K., Hummer, Gerhard, Kranzusch, Philip J.

“…In response to pathogen infection, gasdermin (GSDM) proteins form membrane pores that induce a host cell death process called pyroptosis 1 – 3 . Studies of…”
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Identification of microRNAs responsive to arbuscular mycorrhizal fungi in Panicum virgatum (switchgrass) by Johnson, Alex C, Pendergast, Thomas H, Chaluvadi, Srinivasa, Bennetzen, Jeffrey L, Devos, Katrien M

“…Abstract Background MicroRNAs (miRNAs) are important post-transcriptional regulators involved in the control of a range of processes, including symbiotic…”
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Neutrophil Depletion Attenuates Placental Ischemia-Induced Hypertension in the Rat by Regal, Jean F, Lillegard, Kathryn E, Bauer, Ashley J, Elmquist, Barbara J, Loeks-Johnson, Alex C, Gilbert, Jeffrey S

“…Preeclampsia is characterized by reduced placental perfusion with placental ischemia and hypertension during pregnancy. Preeclamptic women also exhibit a…”
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