Search Results - "Johnsen, Knut"

Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial by Griffin, Simon J, Dr, Borch-Johnsen, Knut, Prof, Davies, Melanie J, Prof, Khunti, Kamlesh, Prof, Rutten, Guy EHM, PhD, Sandbæk, Annelli, Prof, Sharp, Stephen J, MSc, Simmons, Rebecca K, PhD, van den Donk, Maureen, PhD, Wareham, Nicholas J, Prof, Lauritzen, Torsten, Prof

“…Summary Background Intensive treatment of multiple cardiovascular risk factors can halve mortality among people with established type 2 diabetes. We…”
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Age at initiation and frequency of screening to detect type 2 diabetes: a cost-effectiveness analysis by Kahn, Richard, Dr, Alperin, Peter, MD, Eddy, David, MD, Borch-Johnsen, Knut, MD, Buse, John, MD, Feigelman, Justin, Gregg, Edward, PhD, Holman, Rury R, MD, Kirkman, M Sue, MD, Stern, Michael, MD, Tuomilehto, Jaakko, MD, Wareham, Nick J, Prof

“…Summary Background No clinical trials have assessed the effects or cost-effectiveness of sequential screening strategies to detect new cases of type 2…”
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Development of a Type 2 Diabetes Risk Model From a Panel of Serum Biomarkers From the Inter99 Cohort by Kolberg, Janice A, Jørgensen, Torben, Gerwien, Robert W, Hamren, Sarah, McKenna, Michael P, Moler, Edward, Rowe, Michael W, Urdea, Mickey S, Xu, Xiaomei M, Hansen, Torben, Pedersen, Oluf, Borch-Johnsen, Knut

“…OBJECTIVE: The purpose of this study was to develop a model for assessing the 5-year risk of developing type 2 diabetes from a panel of 64 circulating…”
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Pharmacodynamic mechanisms behind a refractory state in inflammatory bowel disease by Goll, Rasmus, Moe, Øystein K., Johnsen, Kay-Martin, Meyer, Renate, Friestad, Joachim, Gundersen, Mona D., Kileng, Hege, Johnsen, Knut, Florholmen, Jon R.

“…Abstract Background and aims Biological therapy for inflammatory bowel disease is efficient in many cases but not all. The underlying molecular mechanisms…”
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Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining by Kirk, Isa Kristina, Simon, Christian, Banasik, Karina, Holm, Peter Christoffer, Haue, Amalie Dahl, Jensen, Peter Bjødstrup, Juhl Jensen, Lars, Rodríguez, Cristina Leal, Pedersen, Mette Krogh, Eriksson, Robert, Andersen, Henrik Ullits, Almdal, Thomas, Bork-Jensen, Jette, Grarup, Niels, Borch-Johnsen, Knut, Pedersen, Oluf, Pociot, Flemming, Hansen, Torben, Bergholdt, Regine, Rossing, Peter, Brunak, Søren

“…Diabetes is a diverse and complex disease, with considerable variation in phenotypic manifestation and severity. This variation hampers the study of…”
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Is diabetes preventable in the general population? by Jørgensen, Marit Eika, MD, PhD, Borch-Johnsen, Knut, MD, Dr.M.Sc

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The National Diabetes Register by Carstensen, Bendix, Kristensen, Jette Kolding, Marcussen, Morten Munk, Borch-Johnsen, Knut

“…Introduction: A National Diabetes Register was established in the National Board of Health in 2006 following a pilot study showing the feasibility of doing so…”
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A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes by Moltke, Ida, Grarup, Niels, Jørgensen, Marit E., Bjerregaard, Peter, Treebak, Jonas T., Fumagalli, Matteo, Korneliussen, Thorfinn S., Andersen, Marianne A., Nielsen, Thomas S., Krarup, Nikolaj T., Gjesing, Anette P., Zierath, Juleen R., Linneberg, Allan, Wu, Xueli, Sun, Guangqing, Jin, Xin, Al-Aama, Jumana, Wang, Jun, Borch-Johnsen, Knut, Pedersen, Oluf, Nielsen, Rasmus, Albrechtsen, Anders, Hansen, Torben

“…An association mapping study of type-2-diabetes-related quantitative traits in the Greenlandic population identified a common variant in TBC1D4 that increases…”
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Discovery and validation of mucosal TNF expression combined with histological score - a biomarker for personalized treatment in ulcerative colitis by Florholmen, Jon R, Johnsen, Kay-Martin, Meyer, Renate, Olsen, Trine, Moe, Øystein K, Tandberg, Petter, Gundersen, Mona D, Kvamme, Jan-Magnus, Johnsen, Knut, Løitegård, Terje, Raschpichler, Gabriele, Vold, Cecilia, Sørbye, Sveinung W, Goll, Rasmus

“…There are no accurate markers that can predict clinical outcome in ulcerative colitis at time of diagnosis. The aim of this study was to explore a…”
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Microvascular retinopathy in subjects without diabetes: the Inter99 Eye Study by Munch, Inger Christine, Kessel, Line, Borch-Johnsen, Knut, Glümer, Charlotte, Lund-Andersen, Henrik, Larsen, Michael

“… Purpose:  Retinal vascular lesions such as microaneurysms and haemorrhages, while typical of diabetic retinopathy, are also seen in subjects without diabetes…”
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Many sequence variants affecting diversity of adult human height by Kiemeney, Lambertus A, Witjes, J Alfred, Stefansson, Kari, Tryggvadottir, Laufey, Stefansson, Hreinn, Heijer, Martin den, Swinkels, Dorine W, Ingason, Andres, Thorsteinsdottir, Unnur, Becker, Diane M, Thorlacius, Steinunn, Jorgensen, Torben, Walters, G Bragi, Zusmanovich, Pasha, Olafsdottir, Gudridur H, Yanek, Lisa R, Verbeek, Andre L M, Hansen, Torben, Becker, Lewis C, Pedersen, Oluf, Gudbjartsson, Daniel F, Borch-Johnsen, Knut, Steinberg, Stacy, Rafnar, Thorunn, Gylfason, Arnaldur, Helgadottir, Anna, Gulcher, Jeffrey, Thorleifsson, Gudmar, Franke, Barbara, Kong, Augustine, Aben, Katja K, Jonsson, Thorvaldur, Andersen, Gitte, Halldorsson, Bjarni V, Sulem, Patrick, Steinthorsdottir, Valgerdur, Olafsdottir, Elinborg J

“…Adult human height is one of the classical complex human traits. We searched for sequence variants that affect height by scanning the genomes of 25,174…”
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Hemoglobin levels and blood pressure are associated in rural black africans by Rasmussen, Jon B., Mwaniki, David L., Kaduka, Lydia U., Boit, Mike K., Borch-Johnsen, Knut, Friis, Henrik, Christensen, Dirk L.

“…Objectives The association between blood levels of hemoglobin (B‐hgb) and blood pressure (BP) has been widely investigated in Caucasians and Asians but there…”
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Prevalence of self-reported stomach symptoms after consuming milk among indigenous Sami and non-Sami in Northern- and Mid-Norway - the SAMINOR study by Hansen, Ketil Lenert, Brustad, Magritt, Johnsen, Knut

“…The main purpose of this work was to identify the prevalence of self-reported stomach symptoms after consuming milk among Sami and non-Sami adults. A…”
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Low Physical Activity Accentuates the Effect of the FTO rs9939609 Polymorphism on Body Fat Accumulation by ANDREASEN, Camilla H, STENDER-PETERSEN, Kirstine L, CLAUSEN, Jesper O, SANDBAEK, Annelli, LAURITZEN, Torsten, HANSEN, Lars, JØRGENSEN, Torben, PEDERSEN, Oluf, HANSEN, Torben, MOGENSEN, Mette S, TOREKOV, Signe S, WEGNER, Lise, ANDERSEN, Gitte, NIELSEN, Arne L, ALBRECHTSEN, Anders, BORCH-JOHNSEN, Knut, RASMUSSEN, Signe S

“…Low Physical Activity Accentuates the Effect of the FTO rs9939609 Polymorphism on Body Fat Accumulation Camilla H. Andreasen 1 , Kirstine L. Stender-Petersen 1…”
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Fat Distribution and Glucose Intolerance Among Greenland Inuit by JØRGENSEN, Marit Eika, BORCH-JOHNSEN, Knut, STOLK, Ronald, BJERREGAARD, Peter

“…A high amount of subcutaneous fat is suggested to explain the observation of lower obesity-associated metabolic risk among Inuit than among Europeans. We…”
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Studies of the Common DIO2 Thr92Ala Polymorphism and Metabolic Phenotypes in 7342 Danish White Subjects by Grarup, Niels, Andersen, Mette K., Andreasen, Camilla H., Albrechtsen, Anders, Borch-Johnsen, Knut, Jørgensen, Torben, Auwerx, Johan, Schmitz, Ole, Hansen, Torben, Pedersen, Oluf

“…Context: The type 2 iodothyronine deiodinase (D2) catalyzes the conversion of T4 to the active form of thyroid hormone, which is a critical regulator of…”
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Moving to an A1C-Based Diagnosis of Diabetes Has a Different Impact on Prevalence in Different Ethnic Groups by CHRISTENSEN, Dirk L, WITTE, Daniel R, KADUKA, Lydia, JØRGENSEN, Marit E, BORCH-JOHNSEN, Knut, MOHAN, Viswanathan, SHAW, Jonathan E, TABAK, Adam G, VISTISEN, Dorte

“…OBJECTIVE To compare screen-detected diabetes prevalence and the degree of diagnostic agreement by ethnicity with the current oral glucose tolerance test…”
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Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution by Helgason, Agnar, Stefánsson, Kári, Pálsson, Snæbjörn, Thorleifsson, Gudmar, Grant, Struan F A, Emilsson, Valur, Gunnarsdottir, Steinunn, Adeyemo, Adebowale, Chen, Yuanxiu, Chen, Guanjie, Reynisdottir, Inga, Benediktsson, Rafn, Hinney, Anke, Hansen, Torben, Andersen, Gitte, Borch-Johnsen, Knut, Jorgensen, Torben, Schäfer, Helmut, Faruque, Mezbah, Doumatey, Ayo, Zhou, Jie, Wilensky, Robert L, Reilly, Muredach P, Rader, Daniel J, Bagger, Yu, Christiansen, Claus, Sigurdsson, Gunnar, Hebebrand, Johannes, Pedersen, Oluf, Thorsteinsdottir, Unnur, Gulcher, Jeffrey R, Kong, Augustine, Rotimi, Charles

“…We recently described an association between risk of type 2diabetes and variants in the transcription factor 7-like 2 gene (TCF7L2; formerly TCF4), with a…”
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Natural History of Insulin Sensitivity and Insulin Secretion in the Progression From Normal Glucose Tolerance to Impaired Fasting Glycemia and Impaired Glucose Tolerance: The Inter99 Study by Færch, Kristine, Vaag, Allan, Holst, Jens J, Hansen, Torben, Jørgensen, Torben, Borch-Johnsen, Knut

“…OBJECTIVE:--The aim of this study was to describe the natural history of insulin secretion and insulin sensitivity in the development of isolated impaired…”
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Association Testing of Novel Type 2 Diabetes Risk Alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 Loci With Insulin Release, Insulin Sensitivity, and Obesity in a Population-Based Sample of 4,516 Glucose-Tolerant Middle-Aged Danes by GRARUP, Niels, ANDERSEN, Gitte, KRARUP, Nikolaj T, ALBRECHTSEN, Anders, SCHMITZ, Ole, JØRGENSEN, Torben, BORCH-JOHNSEN, Knut, HANSEN, Torben, PEDERSEN, Oluf

“…Association Testing of Novel Type 2 Diabetes Risk Alleles in the JAZF1 , CDC123 / CAMK1D , TSPAN8 , THADA , ADAMTS9 , and NOTCH2 Loci With Insulin Release,…”
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