Search Results - "Johns, Margaret A"

Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds by Horton, John R, Liu, Xu, Gale, Molly, Wu, Lizhen, Shanks, John R, Zhang, Xing, Webber, Philip J, Bell, Joshua S K, Kales, Stephen C, Mott, Bryan T, Rai, Ganesha, Jansen, Daniel J, Henderson, Mark J, Urban, Daniel J, Hall, Matthew D, Simeonov, Anton, Maloney, David J, Johns, Margaret A, Fu, Haian, Jadhav, Ajit, Vertino, Paula M, Yan, Qin, Cheng, Xiaodong

“…The KDM5/JARID1 family of Fe(II)- and α-ketoglutarate-dependent demethylases removes methyl groups from methylated lysine 4 of histone H3. Accumulating…”
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The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies by Li, Zenggang, Ivanov, Andrei A., Su, Rina, Gonzalez-Pecchi, Valentina, Qi, Qi, Liu, Songlin, Webber, Philip, McMillan, Elizabeth, Rusnak, Lauren, Pham, Cau, Chen, Xiaoqian, Mo, Xiulei, Revennaugh, Brian, Zhou, Wei, Marcus, Adam, Harati, Sahar, Chen, Xiang, Johns, Margaret A., White, Michael A., Moreno, Carlos S., Cooper, Lee A. D., Du, Yuhong, Khuri, Fadlo R., Fu, Haian

“…As genomics advances reveal the cancer gene landscape, a daunting task is to understand how these genes contribute to dysregulated oncogenic pathways…”
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Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases by Horton, John R., Engstrom, Amanda, Zoeller, Elizabeth L., Liu, Xu, Shanks, John R., Zhang, Xing, Johns, Margaret A., Vertino, Paula M., Fu, Haian, Cheng, Xiaodong

“…The KDM5/JARID1 family of Fe(II)- and α-ketoglutarate-dependent demethylases remove methyl groups from tri- and dimethylated lysine 4 of histone H3…”
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Antibody Response to COVID-19 mRNA Vaccine in Patients With Lung Cancer After Primary Immunization and Booster: Reactivity to the SARS-CoV-2 WT Virus and Omicron Variant by Valanparambil, Rajesh M, Carlisle, Jennifer, Linderman, Susanne L, Akthar, Akil, Millett, Ralph Linwood, Lai, Lilin, Chang, Andres, McCook-Veal, Ashley A, Switchenko, Jeffrey, Nasti, Tahseen H, Saini, Manpreet, Wieland, Andreas, Manning, Kelly E, Ellis, Madison, Moore, Kathryn M, Foster, Stephanie L, Floyd, Katharine, Davis-Gardner, Meredith E, Edara, Venkata-Viswanadh, Patel, Mit, Steur, Conor, Nooka, Ajay K, Green, Felicia, Johns, Margaret A, O'Brein, Fiona, Shanmugasundaram, Uma, Zarnitsyna, Veronika I, Ahmed, Hasan, Nyhoff, Lindsay E, Mantus, Grace, Garett, Michael, Edupuganti, Srilatha, Behra, Madhusmita, Antia, Rustom, Wrammert, Jens, Suthar, Mehul S, Dhodapkar, Madhav V, Ramalingam, Suresh, Ahmed, Rafi

“…To examine COVID-19 mRNA vaccine-induced binding and neutralizing antibody responses in patients with non-small-cell lung cancer (NSCLC) to SARS-CoV-2 614D…”
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ICBS2012 Catalyzes Robust Response from Global Chemical Biology Community by Johns, Margaret A

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The International Chemical Biology Community Synthesizes a New Society by Johns, Margaret A.

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The International Chemical Biology Society’s Global Mission Crystallizes in Kyoto by Findlay, Brandon, Johns, Margaret A

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MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development by Harati, Sahar, Cooper, Lee A D, Moran, Josue D, Giuste, Felipe O, Du, Yuhong, Ivanov, Andrei A, Johns, Margaret A, Khuri, Fadlo R, Fu, Haian, Moreno, Carlos S

“…Protein-protein interactions (PPIs) mediate the transmission and regulation of oncogenic signals that are essential to cellular proliferation and survival, and…”
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BA.5 bivalent booster vaccination enhances neutralization of XBB.1.5, XBB.1.16 and XBB.1.9 variants in patients with lung cancer by Valanparambil, Rajesh M., Lai, Lilin, Johns, Margaret A., Davis-Gardner, Meredith, Linderman, Susanne L., McPherson, Tarrant Oliver, Chang, Andres, Akhtar, Akil, Gamarra, Estefany L. Bocangel, Matia, Hayley, McCook-Veal, Ashley A., Switchenko, Jeffrey, Nasti, Tahseen H., Green, Felicia, Saini, Manpreet, Wieland, Andreas, Pinsky, Benjamin A., Solis, Daniel, Dhodapkar, Madhav V., Carlisle, Jennifer, Ramalingam, Suresh, Ahmed, Rafi, Suthar, Mehul S.

“…This study reports that most patients with NSCLC had a significant increase in the nAb response to the currently circulating Omicron variants after bivalent…”
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The Emory Chemical Biology Discovery Center: leveraging academic innovation to advance novel targets through HTS and beyond by Johns, Margaret A, Meyerkord-Belton, Cheryl L, Du, Yuhong, Fu, Haian

“…The Emory Chemical Biology Discovery Center (ECBDC) aims to accelerate high throughput biology and translation of biomedical research discoveries into…”
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The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery by Ivanov, Andrei A, Revennaugh, Brian, Rusnak, Lauren, Gonzalez-Pecchi, Valentina, Mo, Xiulei, Johns, Margaret A, Du, Yuhong, Cooper, Lee A D, Moreno, Carlos S, Khuri, Fadlo R, Fu, Haian

“…Abstract Motivation As cancer genomics initiatives move toward comprehensive identification of genetic alterations in cancer, attention is now turning to…”
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AKT1, LKB1, and YAP1 Revealed as MYC Interactors with NanoLuc-Based Protein-Fragment Complementation Assay by Mo, Xiulei, Qi, Qi, Ivanov, Andrei A, Niu, Qiankun, Luo, Yin, Havel, Jonathan, Goetze, Russell, Bell, Sydney, Moreno, Carlos S, Cooper, Lee A D, Johns, Margaret A, Khuri, Fadlo R, Du, Yuhong, Fu, Haian

“…The c-Myc (MYC) transcription factor is a major cancer driver and a well-validated therapeutic target. However, directly targeting MYC has been challenging…”
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Corrigendum: The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies by Li, Zenggang, Ivanov, Andrei A, Su, Rina, Gonzalez-Pecchi, Valentina, Qi, Qi, Liu, Songlin, Webber, Philip, McMillan, Elizabeth, Rusnak, Lauren, Pham, Cau, Chen, Xiaoqian, Mo, Xiulei, Revennaugh, Brian, Zhou, Wei, Marcus, Adam, Harati, Sahar, Chen, Xiang, Johns, Margaret A, White, Michael A, Moreno, Carlos S, Cooper, Lee A D, Du, Yuhong, Khuri, Fadlo R, Fu, Haian

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Correction: Corrigendum: The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies by Li, Zenggang, Ivanov, Andrei A., Su, Rina, Gonzalez-Pecchi, Valentina, Qi, Qi, Liu, Songlin, Webber, Philip, McMillan, Elizabeth, Rusnak, Lauren, Pham, Cau, Chen, Xiaoqian, Mo, Xiulei, Revennaugh, Brian, Zhou, Wei, Marcus, Adam, Harati, Sahar, Chen, Xiang, Johns, Margaret A., White, Michael A., Moreno, Carlos S., Cooper, Lee A. D., Du, Yuhong, Khuri, Fadlo R., Fu, Haian

“…Nature Communications 8: Article number: 14356 (2017); Published: 16 February 2017; Updated: 18 April 2017 The original version of this Article contained an…”
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Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome by CARTER, M. G, JOHNS, M. A, XIAOBEI ZENG, LI ZHOU, ZINK, M. C, MANKOWSKI, J. L, DONOVAN, D. M, BAYLIN, S. B

“…HIC1 is a candidate tumor suppressor gene which is frequently hypermethylated in human tumors, and its location within the Miller-Dieker syndrome's critical…”
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OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc by Ivanov, A A, Gonzalez-Pecchi, V, Khuri, L F, Niu, Q, Wang, Y, Xu, Y, Bai, Y, Mo, X, Prochownik, E V, Johns, M A, Du, Y, Khuri, F R, Fu, H

“…Mitogen-activated protein kinase kinase 3 (MKK3) is a dual threonine/tyrosine protein kinase that regulates inflammation, proliferation and apoptosis through…”
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Abstract PR15: Predicting the essentialities of protein-protein interactions in cancer by Cooper, Lee AD, Moran, Josue D., Li, Zenggang, Du, Yuhong, Harati, Sahar, Ivanov, Andrey A., Webber, Phillip, Havel, Jonathan J., Johns, Margaret A., Fu, Haian, Moreno, Carlos S.

“…Abstract Many protein-protein interactions (PPIs) are essential to cellular proliferation and survival, and thus represent potential targets for novel…”
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Urine-induced reflex ovulation in anovulatory rats may be a vomeronasal effect by JOHNS, MARGARET A, FEDER, HARVEY H, KOMISARUK, BARRY R, MAYER, ANNE D

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Understanding the experience of reflective journaling within the human educative paradigm in a baccalaureate nursing program by Johns, Margaret A

“…The goal of nursing education is to develop practitioners who are knowledgeable, competent and are able to meet the challenges of rapid and continual changes…”
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Enzyme-linked immunosorbent assays in a chromatographic format by Johns, Margaret A., Rosengarten, Laura K., Jackson, Martha, Regnier, Fred E.

“…This paper describes the execution of enzyme-linked immunosorbent assays (ELISA), (i) in immunosorbent columns with antibodies immobilized on porous particles,…”
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