Search Results - "Johns, Josephine M."
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Translational analysis of effects of prenatal cocaine exposure on human infant cries and rat pup ultrasonic vocalizations
Published in PloS one (22-10-2014)“…Spectral and temporal features of human infant crying may detect neurobehavioral effects of prenatal cocaine exposure (PCE). Finding comparable measures of…”
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The translational role of diffusion tensor image analysis in animal models of developmental pathologies
Published in Developmental neuroscience (01-01-2012)“…Diffusion tensor magnetic resonance imaging (DTI) has proven itself a powerful technique for clinical investigation of the neurobiological targets and…”
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Prenatal Cocaine Disrupts Serotonin Signaling-Dependent Behaviors:Implications for Sex Differences, Early Stress and Prenatal SSRI Exposure
Published in Current neuropharmacology (01-09-2011)“…Prenatal cocaine (PC) exposure negatively impacts the developing nervous system, including numerous changes in serotonergic signaling. Cocaine, a competitive…”
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Development of translational methods in spectral analysis of human infant crying and rat pup ultrasonic vocalizations for early neurobehavioral assessment
Published in Frontiers in psychiatry (2011)“…The purpose of this article is to describe the development of translational methods by which spectrum analysis of human infant crying and rat pup ultrasonic…”
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Effect of prenatal cocaine on early postnatal thermoregulation and ultrasonic vocalization production
Published in Frontiers in psychology (2013)“…Prenatal cocaine exposure can alter the postnatal care received by rat pups. Such effects could be caused in part by alterations in pup-produced stimuli that…”
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Simultaneous prenatal ethanol and nicotine exposure affect ethanol consumption, ethanol preference and oxytocin receptor binding in adolescent and adult rats
Published in Neurotoxicology and teratology (01-09-2009)“…Abstract Ethanol consumption and smoking during pregnancy are common, despite the known adverse effects on the fetus. The teratogenicity of each drug…”
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Combined norepinephrine/serotonergic reuptake inhibition: effects on maternal behavior, aggression, and oxytocin in the rat
Published in Frontiers in psychiatry (2011)“…Few systematic studies exist on the effects of chronic reuptake of monoamine neurotransmitter systems during pregnancy on the regulation of maternal behavior…”
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Disruption of maternal parenting circuitry by addictive process: rewiring of reward and stress systems
Published in Frontiers in psychiatry (2011)“…Addiction represents a complex interaction between the reward and stress neural circuits, with increasing drug use reflecting a shift from positive…”
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Effects of prenatal cocaine exposure on early postnatal rodent brain structure and diffusion properties
Published in Neurotoxicology and teratology (01-01-2015)“…Abstract Prenatal cocaine exposure has been associated with numerous behavioral phenotypes in clinical populations, including impulsivity, reduced attention,…”
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Use of fast-scan cyclic voltammetry to assess phasic dopamine release in rat models of early postpartum maternal behavior and neglect
Published in Behavioural pharmacology (01-12-2017)“…Maternal behavior (MB) is a complex response to infant cues, orchestrated by postpartum neurophysiology. Although mesolimbic dopamine contributes toward MB,…”
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Effects of chronic and intermittent cocaine treatment on dominance, aggression, and oxytocin levels in post-lactational rats
Published in Psychopharmacologia (01-08-2010)“…Rationale Little is known about mechanisms underlying female rodent aggression during the late postpartum period with no pups present. Studies of aggression,…”
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Deficits in plasma oxytocin responses and increased negative affect, stress, and blood pressure in mothers with cocaine exposure during pregnancy
Published in Addictive behaviors (01-11-2004)“…In animals, oxytocin enhances maternal behavior and lowers blood pressure (BP) and negative affect, while parturitional cocaine disrupts oxytocin activity and…”
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An Oxytocin Antagonist Infused Into the Central Nucleus of the Amygdala Increases Maternal Aggressive Behavior
Published in Behavioral neuroscience (01-04-2003)“…Decreased oxytocin levels in the amygdalas of rat dams following chronic gestational cocaine exposure have been correlated with heightened maternal aggressive…”
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Oxytocin Responsivity in Mothers of Infants: A Preliminary Study of Relationships With Blood Pressure During Laboratory Stress and Normal Ambulatory Activity
Published in Health psychology (01-11-2000)“…The neuropeptide oxytocin (OT) enhances maternal behavior and decreases blood pressure (BP) and stress responses in animals. Thus, the relationship of OT…”
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Cocaine Exposure and Children's Self-Regulation: Indirect Association via Maternal Harshness
Published in Frontiers in psychiatry (2011)“…This study examined the association between prenatal cocaine exposure and children's self-regulation at 3 years of child age. In addition to direct effects of…”
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Cocaine Treatment and Prenatal Environment Interact to Disrupt Intergenerational Maternal Behavior in Rats
Published in Behavioral neuroscience (01-12-2005)“…The link between impaired maternal behavior (MB) and cocaine treatment could result from drug-induced decreases in maternal reactivity to offspring, prenatal…”
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Use of High Resolution 3D Diffusion Tensor Imaging to Study Brain White Matter Development in Live Neonatal Rats
Published in Frontiers in psychiatry (2011)“…High resolution diffusion tensor imaging (DTI) can provide important information on brain development, yet it is challenging in live neonatal rats due to the…”
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Enduring effects of prenatal cocaine administration on emotional behavior in rats
Published in Physiology & behavior (01-07-2000)“…The present studies sought to determine whether prenatal cocaine administration (15 mg/kg b.i.d. between gestational ages 1–20) had enduring effects on…”
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Cocaine disrupts pup-induced maternal behavior in juvenile and adult rats
Published in Neurotoxicology and teratology (01-11-2007)“…Abstract Impaired onset of maternal behavior in first generation rat dams was previously correlated with rearing by cocaine-treated dams and prenatal cocaine…”
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Presynaptic dopaminergic function is largely unaltered in mesolimbic and mesostriatal terminals of adult rats that were prenatally exposed to cocaine
Published in Brain research (24-01-2003)“…Fast-scan cyclic voltammetry in brain slices and postmortem tissue content assessment were used to evaluate presynaptic dopaminergic function in the caudate…”
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