Search Results - "Johns, Helen L"

Rab6 Dependent Post‐Golgi Trafficking of HSV1 Envelope Proteins to Sites of Virus Envelopment by Johns, Helen L., Gonzalez‐Lopez, Claudia, Sayers, Charlotte L., Hollinshead, Michael, Elliott, Gillian

“…Herpes simplex virus 1 (HSV1) is an enveloped virus that uses undefined transport carriers for trafficking of its glycoproteins to envelopment sites. Screening…”
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Challenge of pigs with classical swine fever viruses after C-strain vaccination reveals remarkably rapid protection and insights into early immunity by Graham, Simon P, Everett, Helen E, Haines, Felicity J, Johns, Helen L, Sosan, Olubukola A, Salguero, Francisco J, Clifford, Derek J, Steinbach, Falko, Drew, Trevor W, Crooke, Helen R

“…Pre-emptive culling is becoming increasingly questioned as a means of controlling animal diseases, including classical swine fever (CSF). This has prompted…”
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A Dominant-Negative Mutant of rab5 Inhibits Infection of Cells by Foot-and-Mouth Disease Virus: Implications for Virus Entry by JOHNS, Helen L, BERRYMAN, Stephen, MONAGHAN, Paul, BELSHAM, Graham J, JACKSON, Terry

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Functional and Structural Similarities between the Internal Ribosome Entry Sites of Hepatitis C Virus and Porcine Teschovirus, a Picornavirus by PISAREV, Andrey V, CHARD, Louisa S, KAKU, Yoshihiro, JOHNS, Helen L, SHATSKY, Ivan N, BELSHAM, Graham J

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Endocytic tubules regulated by Rab GTPases 5 and 11 are used for envelopment of herpes simplex virus by Hollinshead, Michael, Johns, Helen L, Sayers, Charlotte L, Gonzalez-Lopez, Claudia, Smith, Geoffrey L, Elliott, Gillian

“…Enveloped viruses employ diverse and complex strategies for wrapping at cellular membranes, many of which are poorly understood. Here, an ultrastructural study…”
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Association between complete response and outcomes in transplant‐eligible myeloma patients in the era of novel agents by Velde, Helgi, Londhe, Anil, Ataman, Ozlem, Johns, Helen L., Hill, Stephen, Landers, Emma, Berlin, Jesse A.

“…Objectives Achieving complete response (CR) has been linked to improved progression‐free (PFS) and overall (OS) survival in myeloma. A meta‐analysis was…”
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CD1− and CD1+ porcine blood dendritic cells are enriched for the orthologues of the two major mammalian conventional subsets by Edwards, Jane C., Everett, Helen E., Pedrera, Miriam, Mokhtar, Helen, Marchi, Emanuele, Soldevila, Ferran, Kaveh, Daryan A., Hogarth, Philip J., Johns, Helen L., Nunez-Garcia, Javier, Steinbach, Falko, Crooke, Helen R., Graham, Simon P.

“…Conventional dendritic cells (cDC) are professional antigen-presenting cells that induce immune activation or tolerance. Two functionally specialised…”
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Characterisation of vaccine-induced, broadly cross-reactive IFN-γ secreting T cell responses that correlate with rapid protection against classical swine fever virus by Graham, Simon P, Haines, Felicity J, Johns, Helen L, Sosan, Olubukola, La Rocca, S. Anna, Lamp, Benjamin, Rümenapf, Till, Everett, Helen E, Crooke, Helen R

“…Highlights ► Vaccine-induced T cell IFN-γ responses show broad reactivity against CSFV strains. ► T cell epitopes are conserved between CSF and BVD viruses. ►…”
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Factors affecting the infectivity of tissues from pigs with classical swine fever: Thermal inactivation rates and oral infectious dose by Cowan, Lucie, Haines, Felicity J., Everett, Helen E., Crudgington, Bentley, Johns, Helen L., Clifford, Derek, Drew, Trevor W., Crooke, Helen R.

“…•Thermal inactivation rates of CSFV in meat tissues have been determined.•D and Z values allow estimation of thermal inactivation times at any…”
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Importance of Arginine 20 of the Swine Vesicular Disease Virus 2A Protease for Activity and Virulence by INOUE, Toru, ALEXANDERSEN, Soren, CLARK, Angela T, MURPHY, Ciara, QUAN, Melvyn, REID, Scott M, SAKODA, Yoshihiro, JOHNS, Helen L, BELSHAM, Graham J

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The classical swine fever virus N-terminal protease Npro binds to cellular HAX-1 by JOHNS, Helen L, DOCEUL, Virginie, EVERETT, Helen, CROOKE, Helen, CHARLESTON, Bryan, SEAGO, Julian

“…The positive-stranded RNA genome of classical swine fever virus (CSFV) encodes 12 known proteins. The first protein to be translated is the N-terminal protease…”
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Characterisation of virus-specific peripheral blood cell cytokine responses following vaccination or infection with classical swine fever viruses by Graham, Simon P., Everett, Helen E., Johns, Helen L., Haines, Felicity J., Rocca, S. Anna La, Khatri, Meenakshi, Wright, Ian K., Drew, Trevor, Crooke, Helen R.

“…Existing live attenuated classical swine fever virus (CSFV) vaccines provide a rapid onset of complete protection but pose problems in discriminating infected…”
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Endocytic tubules regulated by Rab GTPases 5 and 11 are used for envelopment of herpes simplex virus: HSV1 envelopment by endocytic membranes by Hollinshead, Michael, Johns, Helen L, Sayers, Charlotte L, Gonzalez-Lopez, Claudia, Smith, Geoffrey L, Elliott, Gillian

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The classical swine fever virus N-terminal protease N(pro) binds to cellular HAX-1 by Johns, Helen L, Doceul, Virginie, Everett, Helen, Crooke, Helen, Charleston, Bryan, Seago, Julian

“…The positive-stranded RNA genome of classical swine fever virus (CSFV) encodes 12 known proteins. The first protein to be translated is the N-terminal protease…”
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Characterisation of vaccine-induced, broadly cross-reactive IFN-[gamma] secreting T cell responses that correlate with rapid protection against classical swine fever virus by Graham, Simon P, Haines, Felicity J, Johns, Helen L, Sosan, Olubukola, La Rocca, S Anna, Lamp, Benjamin, Rümenapf, Till, Everett, Helen E, Crooke, Helen R

“…Highlights * Vaccine-induced T cell IFN-γ responses show broad reactivity against CSFV strains. * T cell epitopes are conserved between CSF and BVD viruses. *…”
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