Search Results - "Johns, D. G."

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  1. 1

    Regional Climate Change and Harmful Algal Blooms in the Northeast Atlantic by Edwards, M., Johns, D. G., Leterme, S. C., Svendsen, E., Richardson, A. J.

    Published in Limnology and oceanography (01-03-2006)
    “…We investigated long-term spatial variability in a number of Harmful Algal Blooms (HABs) in the northeast Atlantic and North Sea using data from the Continuous…”
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    Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide by Berry, C, Touyz, R, Dominiczak, A F, Webb, R C, Johns, D G

    “…Angiotensin II (ANG II) is a pleiotropic vasoactive peptide that binds to two distinct receptors: the ANG II type 1 (AT(1)) and type 2 (AT(2)) receptors…”
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    Dewatering of mine tailings using electrokinetic geosynthetics by Fourie, A B, Johns, D G, Jones, CJ FP

    Published in Canadian geotechnical journal (01-02-2007)
    “…Many mining operations produce tailings that dewater very slowly under self-weight consolidation. One way of reducing the water content of such tailings is by…”
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    Urotensin II and renal function in the rat by Song, W., Abdel-Razik, A.E.S., Lu, W., Ao, Z., Johns, D.G., Douglas, S.A., Balment, R.J., Ashton, N.

    Published in Kidney international (01-04-2006)
    “…Urotensin II (UII) is a potent vasoactive hormone in mammals. However, despite its well-known effects on epithelial sodium transport in fish, little is known…”
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    Increased blooms of a dinoflagellate in the NW Atlantic by Johns, D. G., Edwards, M., Richardson, A., Spicer, J. I.

    “…Sampling by the Continuous Plankton Recorder (CPR) over the NW Atlantic from 1960 to 2000 has enabled long-term studies of the larger components of the…”
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    Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells by WEN-YI GAO, SHIRASAKA, T, JOHNS, D. G, BRODER, S, MITSUYA, H

    Published in The Journal of clinical investigation (01-05-1993)
    “…The antiviral activity of azidothymidine (AZT), dideoxycytidine (ddC), and dideoxyinosine (ddI) against HIV-1 was comparatively evaluated in PHA-stimulated…”
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    Continuous Plankton Records: Plankton Atlas of the North Atlantic Ocean (1958–1999). II. Biogeographical charts by Barnard, R, Batten, S D, Beaugrand, G, Buckland, C, Conway, DVP, Edwards, M, Finlayson, J, Gregory, L W, Halliday, N C, John, AWG, Johns, D G, Johnson, AD, Jonas, T D, Lindley, JA

    “…The following CPR Atlas contains the biogeographical distribution of 240 common pelagic plankton taxa of the North Sea and North Atlantic Ocean. The…”
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    Mechanism of 'bystander effect' killing in the herpes simplex thymidine kinase gene therapy model of cancer treatment by ISHII-MORITA, H, AGBARIA, R, MULLEN, C. A, HIRANO, H, KOEPLIN, D. A, RAM, Z, OLDFIELD, E. H, JOHNS, D. G, BLAESE, R. M

    Published in Gene therapy (01-03-1997)
    “…'Bystander' killing of adjacent wild-type tumor cells was seen when tumors transduced with the herpes thymidine kinase gene were treated with the antiviral…”
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    The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects by Johns, D G, Behm, D J, Walker, D J, Ao, Z, Shapland, E M, Daniels, D A, Riddick, M, Dowell, S, Staton, P C, Green, P, Shabon, U, Bao, W, Aiyar, N, Yue, T‐L, Brown, A J, Morrison, A D, Douglas, S A

    Published in British journal of pharmacology (01-11-2007)
    “…Background and purpose: Atypical cannabinoids are thought to cause vasodilatation through an as‐yet unidentified ‘CBx’ receptor. Recent reports suggest GPR55…”
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  10. 10

    Selective depletion of DNA precursors : An evolving strategy for potentiation of dideoxynucleoside activity against human immunodeficiency virus by JOHNS, D. G, GAO, W.-Y

    Published in Biochemical pharmacology (15-05-1998)
    “…Human immunodeficiency virus type 1 (HIV-1) is wholly dependent on its host cell for a variety of essential metabolites. Among the latter are the…”
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    Avascular necrosis in HIV infection by JOHNS, D. G, GILL, M. J

    Published in AIDS (London) (01-10-1999)
    “…Protease-based, highly active antiretroviral therapy (HAART) has had a major beneficial impact on both the survival and the short-term outcomes of HIV-infected…”
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    Long-term toxicity/activity profile of 2',3'-dideoxyinosine in AIDS or AIDS-related complex by Yarchoan, R, Pluda, J M, Thomas, R V, Mitsuya, H, Brouwers, P, Wyvill, K M, Hartman, N, Johns, D G, Broder, S

    Published in The Lancet (British edition) (01-09-1990)
    “…To evaluate the long-term toxicity and activity profile of 2',3'-dideoxyinosine (ddI), a potent inhibitor of human immunodeficiency virus (HIV) replication, in…”
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  14. 14

    Marked in vivo Antiretrovirus Activity of 9-(2-phosphonylmethoxyethyl)adenine, a Selective Anti-Human Immunodeficiency Virus Agent by Balzarini, Jan, Naesens, Lieve, Herdewijn, Piet, Rosenberg, Ivan, Holy, Antonin, Pauwels, Rudi, Baba, Masanori, Johns, David G., De Clercq, Erik

    “…9-(2-Phosphonylmethoxyethyl)adenine (PMEA) is a potent and selective inhibitor of the replication of human immunodeficiency virus (HIV) in vitro in human…”
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    The anti-HTLV-III (anti-HIV) and cytotoxic activity of 2',3'-didehydro-2',3'-dideoxyribonucleosides: a comparison with their parental 2',3'-dideoxyribonucleosides by Balzarini, J, Kang, G J, Dalal, M, Herdewijn, P, De Clercq, E, Broder, S, Johns, D G

    Published in Molecular pharmacology (01-07-1987)
    “…A series of 2',3'-didehydro-2',3'-dideoxyribonucleosides (ddeNs) [i.e., 2',3'-dideoxythymidinene (ddeThd), 2',3'-dideoxyuridinene (ddeUrd),…”
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  16. 16

    Anti-human immunodeficiency virus type 1 activity of hydroxyurea in combination with 2',3'-dideoxynucleosides by Gao, W Y, Johns, D G, Mitsuya, H

    Published in Molecular pharmacology (01-10-1994)
    “…The effects of hydroxyurea (HU), an inhibitor of ribonucleotide reductase, on the replication of human immunodeficiency virus type 1 (HIV-1) in activated…”
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    Metabolic pathways for the activation of the antiretroviral agent 2',3'-dideoxyadenosine in human lymphoid cells by Johnson, M A, Ahluwalia, G, Connelly, M C, Cooney, D A, Broder, S, Johns, D G, Fridland, A

    Published in The Journal of biological chemistry (25-10-1988)
    “…The pathways of 2',3'-dideoxyadenosine (ddAdo) metabolism, a selective inhibitor of the replication of human immunodeficiency virus, were investigated with use…”
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    9-[(2RS)-3-Fluoro-2-Phosphonylmethoxypropyl] Derivatives of Purines: A Class of Highly Selective Antiretroviral Agents In vitro and In vivo by Balzarini, Jan, Holy, A., Jindrich, J., Dvorakova, H., Hao, Z., Snoeck, R., Herdewijn, P., Johns, D. G., De Clercq, Erik

    “…A new class of compounds, 9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] [(RS)-FPMP] derivatives of purines, is described that has selective activity against a…”
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    Factors determining the activity of 2',3'-dideoxynucleosides in suppressing human immunodeficiency virus in vitro by Hao, Z, Cooney, D A, Hartman, N R, Perno, C F, Fridland, A, DeVico, A L, Sarngadharan, M G, Broder, S, Johns, D G

    Published in Molecular pharmacology (01-10-1988)
    “…Mitsuya and Broder [Proc. Natl. Acad. Sci. USA 83:1911-1915 (1986)] demonstrated that every purine (adenosine, guanosine, and inosine) and pyrimidine (cytidine…”
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