Search Results - "John Stephen"
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1
Scientific deceit
Published in Synthese (Dordrecht) (01-01-2021)“…This paper argues for a novel account of deceitful scientific communication, as “wishful speaking”. This concept is of relevance both to philosophy of science…”
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2
Adjacent and Nonadjacent Dipyrimidine Photoproducts as Intrinsic Probes of DNA Secondary and Tertiary Structure
Published in Photochemistry and photobiology (01-03-2023)“…While the photochemistry of duplex DNA has been extensively studied, the photochemistry of nonduplex DNA structures is largely unexplored. Because the…”
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3
A Review on the Mechanisms of Blood-Flow Restriction Resistance Training-Induced Muscle Hypertrophy
Published in Sports medicine (Auckland) (01-02-2015)“…It has traditionally been believed that resistance training can only induce muscle growth when the exercise intensity is greater than 65 % of the 1-repetition…”
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Multi-omic machine learning predictor of breast cancer therapy response
Published in Nature (London) (27-01-2022)“…Breast cancers are complex ecosystems of malignant cells and the tumour microenvironment 1 . The composition of these tumour ecosystems and interactions within…”
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Ability of the Putative Decomposition Products of 2,3‐dioxetanes of Indoles to Photosensitize Cyclobutane Pyrimidine Dimer (CPD) Formation and its Implications for the “Dark” (Chemisensitized) Pathway to CPDs in Melanocytes
Published in Photochemistry and photobiology (01-03-2022)“…The formation of cyclobutane pyrimidine dimers (CPDs) by a “dark” pathway in melanocytes has been attributed to chemisensitization by dioxetanes produced from…”
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Neurological intervention transition model for dynamic prediction of good outcome in spontaneous subarachnoid haemorrhage
Published in Scientific reports (18-01-2024)“…Deterioration of neurovascular conditions can be rapid in patients with spontaneous subarachnoid haemorrhage (SAH) and often lead to poor clinical outcomes…”
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Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups
Published in Nature (London) (01-03-2019)“…The rates and routes of lethal systemic spread in breast cancer are poorly understood owing to a lack of molecularly characterized patient cohorts with…”
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8
Characteristics of the Summating Potential Measured Across a Cochlear Implant Array as an Indicator of Cochlear Function
Published in Ear and hearing (01-09-2023)“…The underlying state of cochlear and neural tissue function is known to affect postoperative speech perception following cochlear implantation. The ability to…”
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9
Defect Engineering of Oxygen‐Deficient Manganese Oxide to Achieve High‐Performing Aqueous Zinc Ion Battery
Published in Advanced energy materials (11-04-2019)“…A major limitation of MnO2 in aqueous Zn/MnO2 ion battery applications is the poor utilization of its electrochemical active surface area. Herein, it is shown…”
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10
ZnO Nanosheets Abundant in Oxygen Vacancies Derived from Metal‐Organic Frameworks for ppb‐Level Gas Sensing
Published in Advanced materials (Weinheim) (01-03-2019)“…Surmounting the inhomogeniety issue of gas sensors and realizing their reproducible ppb‐level gas sensing are highly desirable for widespread deployments of…”
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11
The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences
Published in Nature communications (22-12-2020)“…Molecular profiling of breast cancer has enabled the development of more robust molecular prognostic signatures and therapeutic options for breast cancer…”
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12
Personalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer
Published in Science translational medicine (07-08-2019)“…Longitudinal analysis of circulating tumor DNA (ctDNA) has shown promise for monitoring treatment response. However, most current methods lack adequate…”
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13
A multi-layered model of Newtonian viscous liquid, fiber-reinforced and poro-elastic media over a self-weighted half-space to investigate the SH-wave interactions
Published in Mechanics of advanced materials and structures (18-11-2024)“…The present study is carried out to investigate the regulation phenomena of SH-waves into a multi-layered structure of Newtonian viscous liquid,…”
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14
The dark side of sunlight and melanoma
Published in Science (American Association for the Advancement of Science) (20-02-2015)“…UV-initiated DNA photodamage in melanocytes is found to continue in the dark [Also see Research Article by Premi et al. ] Skin cancer is the most prevalent…”
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The effect of flanking bases on direct and triplet sensitized cyclobutane pyrimidine dimer formation in DNA depends on the dipyrimidine, wavelength and the photosensitizer
Published in Nucleic acids research (07-05-2021)“…Abstract Cyclobutane pyrimidine dimers (CPDs) are the major products of DNA produced by direct absorption of UV light, and result in C to T mutations linked to…”
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Epitaxial Growth of Centimeter-Scale Single-Crystal MoS2 Monolayer on Au(111)
Published in ACS nano (28-04-2020)“…Two-dimensional (2D) semiconducting transition metal dichalcogenides (TMDs) have emerged as attractive platforms in next-generation nanoelectronics and…”
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DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
Published in Nature communications (13-09-2021)“…DNA methylation is aberrant in cancer, but the dynamics, regulatory role and clinical implications of such epigenetic changes are still poorly understood…”
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Perceptions of TB-HIV comorbidity among the Nomads in Adamawa State, Nigeria
Published in BMC public health (01-05-2024)“…The recalcitrance of Mycobacterium tuberculosis (MTB) to eradication was related to achieving a nonreplicating (dormant) state and the increasing global burden…”
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Power-efficient low-temperature woven coiled fibre actuator for wearable applications
Published in Scientific reports (04-11-2016)“…A fibre actuator that generates a large strain with high specific power represents a promising strategy to develop novel wearable devices and robotics. We…”
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Comparison of tumor‐informed and tumor‐naïve sequencing assays for ctDNA detection in breast cancer
Published in EMBO molecular medicine (07-06-2023)“…Analysis of circulating tumor DNA (ctDNA) to monitor cancer dynamics and detect minimal residual disease has been an area of increasing interest. Multiple…”
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