Search Results - "John Sadgrove, Nicholas"
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Comment on Pyrrolizidine Alkaloids and Terpenes from Senecio (Asteraceae): Chemistry and Research Gaps in Africa
Published in Molecules (Basel, Switzerland) (13-12-2022)“…The genus is one of the largest in Asteraceae. There are thousands of species across the globe, either confirmed or awaiting taxonomic delimitation. While the…”
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Purely Australian Essential Oils Past and Present: Chemical Diversity, Authenticity, Bioactivity, and Commercial Value
Published in Diversity (Basel) (01-02-2022)“…In this comprehensive commentary, Australian essential oils and their components are listed and discussed in the context of their value to industry and…”
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From Petri Dish to Patient: Bioavailability Estimation and Mechanism of Action for Antimicrobial and Immunomodulatory Natural Products
Published in Frontiers in microbiology (31-10-2019)“…The new era of multidrug resistance of pathogens against frontline antibiotics has compromised the immense therapeutic gains of the ‘golden age,’ stimulating a…”
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Cosmetopoeia of African Plants in Hair Treatment and Care: Topical Nutrition and the Antidiabetic Connection?
Published in Diversity (Basel) (01-02-2024)“…To make the distinction against pharmaceuticals, natural product medicines are more accurately denoted as nutritional therapies. In the context of topical…”
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Isolation and characterisation of (−)-genifuranal: The principal antimicrobial component in traditional smoking applications of Eremophila longifolia (Scrophulariaceae) by Australian aboriginal peoples
Published in Journal of ethnopharmacology (03-07-2014)“…Eremophila longifolia is considered by some Australian Aboriginal tribal groups to be among the most significant of the medicinal plants in contemporary and…”
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Pharmacology of Natural Volatiles and Essential Oils in Food, Therapy, and Disease Prophylaxis
Published in Frontiers in pharmacology (21-10-2021)“…This commentary critically examines the modern paradigm of natural volatiles in 'medical aromatherapy', first by explaining the semantics of natural volatiles…”
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Topical and nutricosmetic products for healthy hair and dermal antiaging using “dual‐acting” (2 for 1) plant‐based peptides, hormones, and cannabinoids
Published in FASEB bioAdvances (01-08-2021)“…One of the side effects of oral antiaging retinoids is increased hair shedding. Retinoids promote the expression of TGF‐β2 from fibroblasts, which stimulate…”
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Insecticidal activity of essential oils from Piper aduncum against Ctenocephalides felis felis: a promising approach for flea control
Published in Revista brasileira de parasitologia veterinaria (01-01-2024)“…Piper aduncum L., a Brazilian medicinal plant, is known for its bioactive properties, including repellent and insecticidal effects. This study investigated the…”
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Advanced Chemophenetic Analysis of Essential Oil from Leaves of Piper gaudichaudianum Kunth (Piperaceae) Using a New Reduction-Oxidation Index to Explore Seasonal and Circadian Rhythms
Published in Plants (Basel) (06-10-2021)“…The aromatic species Piper gaudichaudianum Kunth (Piperaceae) is widely used in Brazil for medicinal and ritualistic applications. In the current study,…”
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Phenoplasticity of Essential Oils from Two Species of Piper (Piperaceae): Comparing Wild Specimens and Bi-Generational Monoclonal Cultivars
Published in Plants (Basel) (04-07-2022)“…This study tested the hypothesis that “clonal chemical heritability is a crucial factor for the conservation of chemical uniformity of Piper essential oils in…”
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A New Antimicrobial Phenylpropanol from the Leaves of Tabernaemontana inconspicua Stapf. (Apocynaceae) Inhibits Pathogenic Gram-Negative Bacteria
Published in Antibiotics (Basel) (17-01-2022)“…A chemical investigation of the leaves of Stapf. led to the isolation of a new phenylpropanol derivative, namely irisdichototin G ( ), together with nine known…”
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Honest nutraceuticals, cosmetics, therapies, and foods (NCTFs): standardization and safety of natural products
Published in Critical reviews in food science and nutrition (2022)“…With the increasing demand for natural products by the consumer in the marketplace it is necessary to see a proportional increase in behind-the-scenes science…”
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The ‘bald’ phenotype (androgenetic alopecia) is caused by the high glycaemic, high cholesterol and low mineral ‘western diet’
Published in Trends in food science & technology (01-10-2021)“…The success of 5α-reductase inhibitors in the 1990s vindicated the role of androgens and cast doubt on the role of diet in androgenetic alopecia (AGA)…”
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Comparing essential oils from Australia's ‘Victorian Christmas Bush’ (Prostanthera lasianthos Labill., Lamiaceae) to closely allied new species: Phenotypic plasticity and taxonomic variability
Published in Phytochemistry (Oxford) (01-08-2020)“…Prostanthera lasianthos (Lamiaceae) is commonly referred to as the ‘Victorian Christmas Bush’, a name that derives from the floral display it gives in the…”
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The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance
Published in Journal of ethnopharmacology (05-12-2018)“…Research in the past half a century has gradually sketched the biological mechanism leading to androgenetic alopecia (AGA). Until recently the aetiological…”
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Comment on Pyrrolizidine Alkaloids and Terpenes from ISenecio/I : Chemistry and Research Gaps in Africa
Published in Molecules (Basel, Switzerland) (01-12-2022)“…The genus Senecio is one of the largest in Asteraceae. There are thousands of species across the globe, either confirmed or awaiting taxonomic delimitation…”
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Cytogeography of essential oil chemotypes of Eremophila longifolia F. Muell (Scrophulariaceae)
Published in Phytochemistry (Oxford) (01-09-2014)“…•E. longifolia is both diploid and tetraploid, in congruence with chemotypes.•Diploid cytotypes produce very high yields of essential oils.•Tetraploid…”
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Chemical and biological characterisation of solvent extracts and essential oils from leaves and fruit of two Australian species of Pittosporum (Pittosporaceae) used in aboriginal medicinal practice
Published in Journal of ethnopharmacology (13-02-2013)“…Although no known medicinal use for Pittosporum undulatum Vent. (Pittosporaceae) has been recorded, anecdotal evidence suggests that Australian Aboriginal…”
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Medicinal compounds, chemically and biologically characterised from extracts of Australian Callitris endlicheri and C.glaucophylla (Cupressaceae): Used traditionally in Aboriginal and colonial pharmacopoeia
Published in Journal of ethnopharmacology (14-05-2014)“…Callitrisendlicheri and C.glaucophylla were highly valued by Australian Aboriginal people for use in medicinal applications. Pine needles were prepared using…”
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