Search Results - "John A. Hammond"

IgMAT: immunoglobulin sequence multi-species annotation tool for any species including those with incomplete antibody annotation or unusual characteristics by Dorey-Robinson, Daniel, Maccari, Giuseppe, Hammond, John A

“…The advent and continual improvement of high-throughput sequencing technologies has made immunoglobulin repertoire sequencing accessible and informative…”
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The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins by Conceicao, Carina, Thakur, Nazia, Human, Stacey, Kelly, James T, Logan, Leanne, Bialy, Dagmara, Bhat, Sushant, Stevenson-Leggett, Phoebe, Zagrajek, Adrian K, Hollinghurst, Philippa, Varga, Michal, Tsirigoti, Christina, Tully, Matthew, Chiu, Chris, Moffat, Katy, Silesian, Adrian Paul, Hammond, John A, Maier, Helena J, Bickerton, Erica, Shelton, Holly, Dietrich, Isabelle, Graham, Stephen C, Bailey, Dalan

“…SARS Coronavirus 2 (SARS-CoV-2) emerged in late 2019, leading to the Coronavirus Disease 2019 (COVID-19) pandemic that continues to cause significant global…”
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The 2024 IPD-MHC database update: a comprehensive resource for major histocompatibility complex studies by Maccari, Giuseppe, Robinson, James, Barker, Dominic J, Yates, Andrew D, Hammond, John A, Marsh, Steven G E

“…The IPD-MHC Database project (http://www.ebi.ac.uk/ipd/mhc/) serves as a comprehensive and expertly curated repository for major histocompatibility complex…”
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Working hard to belong: a qualitative study exploring students from black, Asian and minority ethnic backgrounds experiences of pre-registration physiotherapy education by Hammond, John A, Williams, Annabel, Walker, Saskia, Norris, Meriel

“…Previous research has demonstrated that attainment inequalities exist for students from Black Asian and Minority Ethnic (BAME) groups in pre-registration…”
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Splicing Site Recognition by Synergy of Three Domains in Splicing Factor RBM10 by Serrano, Pedro, Hammond, John A, Geralt, Michael, Wüthrich, Kurt

“…Splicing factor RBM10 and its close homologues RBM5 and RBM6 govern the splicing of oncogenes such as Fas, NUMB, and Bcl-X. The molecular architecture of these…”
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Fc-Mediated Functions of Porcine IgG Subclasses by Paudyal, Basudev, Mwangi, William, Rijal, Pramila, Schwartz, John C, Noble, Alistair, Shaw, Andrew, Sealy, Joshua E, Bonnet-Di Placido, Marie, Graham, Simon P, Townsend, Alain, Hammond, John A, Tchilian, Elma

“…The pig is an important agricultural species and powerful biomedical model. We have established the pig, a large natural host animal for influenza with many…”
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Distinct effector functions mediated by Fc regions of bovine IgG subclasses and their interaction with Fc gamma receptors by Noble, Alistair, Paudyal, Basudev, Schwartz, John C, Mwangi, William, Munir, Danish, Tchilian, Elma, Hammond, John A, Graham, Simon P

“…Cattle possess three IgG subclasses. However, the key immune functions, including complement and NK cell activation, and enhancement of phagocytosis, are not…”
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Common cancer in a wild animal: the California sea lion (Zalophus californianus) as an emerging model for carcinogenesis by Browning, Helen M., Gulland, Frances M. D., Hammond, John A., Colegrove, Kathleen M., Hall, Ailsa J.

“…Naturally occurring cancers in non-laboratory species have great potential in helping to decipher the often complex causes of neoplasia. Wild animal models…”
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Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans by Holzer, Barbara, Rijal, Pramila, McNee, Adam, Paudyal, Basudev, Martini, Veronica, Clark, Becky, Manjegowda, Tanuja, Salguero, Francisco J, Bessell, Emily, Schwartz, John C, Moffat, Katy, Pedrera, Miriam, Graham, Simon P, Noble, Alistair, Bonnet-Di Placido, Marie, La Ragione, Roberto M, Mwangi, William, Beverley, Peter, McCauley, John W, Daniels, Rodney S, Hammond, John A, Townsend, Alain R, Tchilian, Elma

“…Pigs are natural hosts for the same subtypes of influenza A viruses as humans and integrally involved in virus evolution with frequent interspecies…”
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Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig by Tungatt, Katie, Dolton, Garry, Morgan, Sophie B, Attaf, Meriem, Fuller, Anna, Whalley, Thomas, Hemmink, Johanneke D, Porter, Emily, Szomolay, Barbara, Montoya, Maria, Hammond, John A, Miles, John J, Cole, David K, Townsend, Alain, Bailey, Mick, Rizkallah, Pierre J, Charleston, Bryan, Tchilian, Elma, Sewell, Andrew K

“…There is increasing evidence that induction of local immune responses is a key component of effective vaccines. For respiratory pathogens, for example…”
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Low Dose Pig Anti-Influenza Virus Monoclonal Antibodies Reduce Lung Pathology but Do Not Prevent Virus Shedding by Paudyal, Basudev, McNee, Adam, Rijal, Pramila, Carr, B Veronica, Nunez, Alejandro, McCauley, John, Daniels, Rodney S, Townsend, Alain R, Hammond, John A, Tchilian, Elma

“…We have established the pig, a large natural host animal for influenza, with many physiological similarities to humans, as a robust model for testing the…”
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TLR15 is unique to avian and reptilian lineages and recognizes a yeast-derived agonist by Boyd, Amy C, Peroval, Marylene Y, Hammond, John A, Prickett, Michael D, Young, John R, Smith, Adrian L

“…The TLRs represent a family of pattern recognition receptors critical in the induction of vertebrate immune responses. Between 10 and 13 different TLR genes…”
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The Veterinary Immunological Toolbox: Past, Present, and Future by Entrican, Gary, Lunney, Joan K, Wattegedera, Sean R, Mwangi, William, Hope, Jayne C, Hammond, John A

“…It is well-recognized that research capability in veterinary species is restricted by a lack of immunological reagents relative to the extensive toolboxes for…”
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Cattle NK Cell Heterogeneity and the Influence of MHC Class I by Allan, Alasdair J, Sanderson, Nicholas D, Gubbins, Simon, Ellis, Shirley A, Hammond, John A

“…Primate and rodent NK cells form highly heterogeneous lymphocyte populations owing to the differential expression of germline-encoded receptors. Many of these…”
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The Structure, Evolution, and Gene Expression Within the Caprine Leukocyte Receptor Complex by Schwartz, John C, Sanderson, Nicholas D, Bickhart, Derek M, Smith, Timothy P L, Hammond, John A

“…The leukocyte receptor complex (LRC) encodes a large number of immunoglobulin (Ig)-like receptors involved in the immune response, particularly in modulating…”
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RNAseq Reveals the Contribution of Interferon Stimulated Genes to the Increased Host Defense and Decreased PPR Viral Replication in Cattle by Tirumurugaan, Krishnaswamy Gopalan, Pawar, Rahul Mohanchandra, Dhinakar Raj, Gopal, Thangavelu, Arthanari, Hammond, John A, Parida, Satya

“…(PPRV) is known to replicate in a wide variety of ruminants causing very species-specific clinical symptoms. Small ruminants (goats and sheep) are susceptible…”
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Correction: Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans by Holzer, Barbara, Rijal, Pramila, McNee, Adam, Paudyal, Basudev, Martini, Veronica, Clark, Becky, Manjegowda, Tanuja, Salguero, Francisco J, Bessell, Emily, Schwartz, John C, Moffat, Katy, Pedrera, Miriam, Graham, Simon P, Noble, Alistair, Placido, Marie Bonnet-Di, La Ragione, Roberto M, Mwangi, William, Beverley, Peter, McCauley, John W, Daniels, Rodney S, Hammond, John A, Townsend, Alain R, Tchilian, Elma

“…[This corrects the article DOI: 10.1371/journal.ppat.1009330.]…”
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Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket by Craveur, Pierrick, Gres, Anna T, Kirby, Karen A, Liu, Dandan, Hammond, John A, Deng, Yisong, Forli, Stefano, Goodsell, David S, Williamson, James R, Sarafianos, Stefan G, Olson, Arthur J

“…HIV-1 capsid protein (CA) plays critical roles in both early and late stages of the viral replication cycle. Mutagenesis and structural experiments have…”
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Evidence for a genetic basis of urogenital carcinoma in the wild California sea lion by Browning, Helen M., Acevedo-Whitehouse, Karina, Gulland, Frances M. D., Hall, Ailsa J., Finlayson, Jeanie, Dagleish, Mark P., Billington, Karen J., Colegrove, Kathleen, Hammond, John A.

“…Although neoplasia is a major cause of mortality in humans and domestic animals, it has rarely been described in wildlife species. One of the few examples is a…”
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A Customizable Suite of Methods to Sequence and Annotate Cattle Antibodies by Ramirez Valdez, Kristel, Nzau, Benjamin, Dorey-Robinson, Daniel, Jarman, Michael, Nyagwange, James, Schwartz, John C, Freimanis, Graham, Steyn, Angela W, Warimwe, George M, Morrison, Liam J, Mwangi, William, Charleston, Bryan, Bonnet-Di Placido, Marie, Hammond, John A

“…Studying the antibody response to infection or vaccination is essential for developing more effective vaccines and therapeutics. Advances in high-throughput…”
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