Search Results - "John, John St"

Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection by Ulz, Peter, Perakis, Samantha, Zhou, Qing, Moser, Tina, Belic, Jelena, Lazzeri, Isaac, Wölfler, Albert, Zebisch, Armin, Gerger, Armin, Pristauz, Gunda, Petru, Edgar, White, Brandon, Roberts, Charles E. S., John, John St, Schimek, Michael G., Geigl, Jochen B., Bauernhofer, Thomas, Sill, Heinz, Bock, Christoph, Heitzer, Ellen, Speicher, Michael R.

“…Deregulation of transcription factors (TFs) is an important driver of tumorigenesis, but non-invasive assays for assessing transcription factor activity are…”
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Adaptive immune responses to primary and secondary dengue virus infections by St. John, Ashley L., Rathore, Abhay P. S.

“…Dengue is the leading mosquito-borne viral illness infecting humans. Owing to the circulation of multiple serotypes, global expansion of the disease and recent…”
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Genomic evidence for island population conversion resolves conflicting theories of polar bear evolution by Cahill, James A, Green, Richard E, Fulton, Tara L, Stiller, Mathias, Jay, Flora, Ovsyanikov, Nikita, Salamzade, Rauf, St John, John, Stirling, Ian, Slatkin, Montgomery, Shapiro, Beth

“…Despite extensive genetic analysis, the evolutionary relationship between polar bears (Ursus maritimus) and brown bears (U. arctos) remains unclear. The two…”
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Toward a new understanding of the links between poverty and illegal wildlife hunting by Duffy, Rosaleen, St John, Freya A. V, Büscher, Bram, Brockington, Dan

“…Conservation organizations have increasingly raised concerns about escalating rates of illegal hunting and trade in wildlife. Previous studies have concluded…”
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Review Paper: The Shape of Phylogenetic Treespace by Katherine, St. John

“…Trees are a canonical structure for representing evolutionary histories. Many popular criteria used to infer optimal trees are computationally hard, and the…”
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Prediction of organic homolytic bond dissociation enthalpies at near chemical accuracy with sub-second computational cost by St. John, Peter C., Guan, Yanfei, Kim, Yeonjoon, Kim, Seonah, Paton, Robert S.

“…Bond dissociation enthalpies (BDEs) of organic molecules play a fundamental role in determining chemical reactivity and selectivity. However, BDE computations…”
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Advances in understanding nociception and neuropathic pain by St John Smith, Ewan

“…Pain results from the activation of a subset of sensory neurones termed nociceptors and has evolved as a “detect and protect” mechanism. However, lesion or…”
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Japanese encephalitis virus and its mechanisms of neuroinvasion by Hsieh, Justin T, St John, Ashley L

“…About the Authors: Justin T. Hsieh Affiliation: Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, Singapore ORCID…”
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Mast cell-orchestrated immunity to pathogens by Abraham, Soman N, St. John, Ashley L

“…Key Points Although widely associated with various inflammatory diseases, mast cells have an evolutionarily conserved role in host defence and have been shown…”
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The SARS-coronavirus papain-like protease: Structure, function and inhibition by designed antiviral compounds by Báez-Santos, Yahira M., St. John, Sarah E., Mesecar, Andrew D.

“…•HTS and structure-based design produced naphthalene-based lead compounds with inhibition of SARS-CoV PLpro in the nM range.•These naphthalene-based lead…”
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The prevalence of multimorbidity and associations with lifestyle factors among middle-aged Canadians: an analysis of Canadian Longitudinal Study on Aging data by Sakib, Mohammad Nazmus, Shooshtari, Shahin, St John, Philip, Menec, Verena

“…Multimorbidity can be defined as the presence of more than one chronic condition in an individual. Research on multimorbidity has predominantly focused on…”
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The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance-challenges and future research opportunities by Barratt, Christopher L R, Björndahl, Lars, De Jonge, Christopher J, Lamb, Dolores J, Osorio Martini, Francisco, McLachlan, Robert, Oates, Robert D, van der Poel, Sheryl, St John, Bianca, Sigman, Mark, Sokol, Rebecca, Tournaye, Herman

“…Herein, we describe the consensus guideline methodology, summarize the evidence-based recommendations we provided to the World Health Organization (WHO) for…”
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Importance of Engineered and Learned Molecular Representations in Predicting Organic Reactivity, Selectivity, and Chemical Properties by Gallegos, Liliana C, Luchini, Guilian, St. John, Peter C, Kim, Seonah, Paton, Robert S

“…Conspectus Machine-readable chemical structure representations are foundational in all attempts to harness machine learning for the prediction of reactivities,…”
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Addressing human-tiger conflict using socio-ecological information on tolerance and risk by Struebig, Matthew J., Linkie, Matthew, Deere, Nicolas J., Martyr, Deborah J., Millyanawati, Betty, Faulkner, Sally C., Le Comber, Steven C., Mangunjaya, Fachruddin M., Leader-Williams, Nigel, McKay, Jeanne E., St. John, Freya A. V.

“…Tigers are critically endangered due to deforestation and persecution. Yet in places, Sumatran tigers ( Panthera tigris sumatrae ) continue to coexist with…”
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Cross-Reactive Immunity Among Flaviviruses by Rathore, Abhay P S, St John, Ashley L

“…Flaviviruses consist of significant human pathogens responsible for hundreds of millions of infections each year. Their antigenic relationships generate immune…”
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Entrepreneurial crowdfunding backer motivations: a latent Dirichlet allocation approach by St John, Jeremy, St John, Karen, Han, Bo

“…PurposeThis study furthers one’s understanding of the motivations of the crowdfunding crowd by empirically examining critical factors that influence the…”
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Biventricular Pacing for Atrioventricular Block and Systolic Dysfunction by Curtis, Anne B, Worley, Seth J, Adamson, Philip B, Chung, Eugene S, Niazi, Imran, Sherfesee, Lou, Shinn, Timothy, St. John Sutton, Martin

“…In this trial, patients with atrioventricular block and systolic dysfunction were randomly assigned to receive biventricular or right ventricular pacing…”
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Japanese encephalitis virus neuropenetrance is driven by mast cell chymase by Hsieh, Justin T., Rathore, Abhay P. S., Soundarajan, Gayathri, St. John, Ashley L.

“…Japanese encephalitis virus (JEV) is a leading cause of viral encephalitis. However, the mechanisms of JEV penetration of the blood-brain-barrier (BBB) remain…”
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Innate immunity and its regulation by mast cells by St John, Ashley L, Abraham, Soman N

“…Mast cells (MCs), which are granulated tissue-resident cells of hematopoietic lineage, constitute a major sensory arm of the innate immune system. In this…”
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Ventricular-Arterial Coupling, Remodeling, and Prognosis in Chronic Heart Failure by Ky, Bonnie, MD, MSCE, French, Benjamin, PhD, May Khan, Abigail, MD, Plappert, Ted, CVT, Wang, Andrew, BA, Chirinos, Julio A., MD, Fang, James C., MD, Sweitzer, Nancy K., MD, PhD, Borlaug, Barry A., MD, Kass, David A., MD, St. John Sutton, Martin, MBBS, Cappola, Thomas P., MD, ScM

“…Objectives The objective of this study was to compare the physiological determinants of ejection fraction (EF)—ventricular size, contractile function, and…”
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