Search Results - "John, Arun"

Vps13-Mcp1 interact at vacuole-mitochondria interfaces and bypass ER-mitochondria contact sites by John Peter, Arun T, Herrmann, Beatrice, Antunes, Diana, Rapaport, Doron, Dimmer, Kai Stefan, Kornmann, Benoît

“…Membrane contact sites between endoplasmic reticulum (ER) and mitochondria, mediated by the ER-mitochondria encounter structure (ERMES) complex, are critical…”
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ER–mitochondria contact sites in yeast: beyond the myths of ERMES by Lang, Alexander, John Peter, Arun T, Kornmann, Benoît

“…A standout feature of eukaryotic cells is the presence of organelles with distinct chemical compositions and physical properties, which aid in the…”
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Unbiased MD simulations identify lipid binding sites in lipid transfer proteins by Srinivasan, Sriraksha, Álvarez, Daniel, John Peter, Arun T, Vanni, Stefano

“…The characterization of lipid binding to lipid transfer proteins (LTPs) is fundamental to understand their molecular mechanism. However, several structures of…”
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ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13 by Lang, Alexander B, John Peter, Arun T, Walter, Peter, Kornmann, Benoît

“…The endoplasmic reticulum-mitochondria encounter structure (ERMES) complex tethers the endoplasmic reticulum and the mitochondria. It is thought to facilitate…”
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BRAF- and MAP2K1-Negative Multisystem Langerhans Cell Histiocytosis in an Elderly Patient by Kothari, Rohit, Bhatnagar, Anuj, Varghese, Jeenu, Kishore, Karthi, Chand, Satish, Mitra, Debdeep, John, Arun R

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Rewiring phospholipid biosynthesis reveals resilience to membrane perturbations and uncovers regulators of lipid homeostasis by John Peter, Arun T, van Schie, Sabine N S, Cheung, Ngaam J, Michel, Agnès H, Peter, Matthias, Kornmann, Benoît

“…The organelles of eukaryotic cells differ in their membrane lipid composition. This heterogeneity is achieved by the localization of lipid synthesizing and…”
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The conformational plasticity of structurally unrelated lipid transport proteins correlates with their mode of action by Srinivasan, Sriraksha, Di Luca, Andrea, Álvarez, Daniel, John Peter, Arun T, Gehin, Charlotte, Lone, Museer A, Hornemann, Thorsten, D'Angelo, Giovanni, Vanni, Stefano

“…Lipid transfer proteins (LTPs) are key players in cellular homeostasis and regulation, as they coordinate the exchange of lipids between different cellular…”
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Burkitt lymphoma with disseminated pleuroperitoneal and visceral lymphomatosis: Autopsy diagnosis of an unusual case by Guleria, Prerna, Guleria, Bhupesh, Ahuja, Ankur, Chatterjee, Tathagata, John, Arun R

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S2320 The Tale of the Telangiectatic Anemic by Reyes, Jonathan Vincent M., Bieber, Christine, Ahmad, Saad, Seen, Tasur, John, Arun

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De novo squamous cell carcinoma presenting as nodulo‐ulcerative lesions on inguinal regions mimicking venereal disease by Singh, Gautam K., Arora, Sandeep, Das, Pankaj, John, Arun R., Gupta, Akanksha

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Pharmacophore modelling and molecular dynamics simulation to identify novel molecules targeting catechol-O-methyltransferase and dopamine D3 receptor to combat Parkinson’s disease by Joy, Amitha, Menon, Sidharth, Thomas, Neethu Mariam, Christy, Meha, Menon, Aiswarya D., John, Arun

“…Parkinson’s disease is a neurological illness that slowly impairs a small number of neurons in the substantia nigra, a part of the brain. Dopamine, a substance…”
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Accurate prediction of protein function using statistics-informed graph networks by Jang, Yaan J., Qin, Qi-Qi, Huang, Si-Yu, Peter, Arun T. John, Ding, Xue-Ming, Kornmann, Benoît

“…Understanding protein function is pivotal in comprehending the intricate mechanisms that underlie many crucial biological activities, with far-reaching…”
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The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3 by John Peter, Arun T, Lachmann, Jens, Rana, Meenakshi, Bunge, Madeleine, Cabrera, Margarita, Ungermann, Christian

“…Membrane microcompartments of the early endosomes serve as a sorting and signaling platform, where receptors are either recycled back to the plasma membrane or…”
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Exploring sesquiterpene lactone as a dual therapeutic agent for diabetes and oxidative stress: insights into PI3K/AKT modulation by Velumani, Kadhirmathiyan, John, Arun, Shaik, Mohammed Rafi, Hussain, Shaik Althaf, Guru, Ajay, Issac, Praveen Kumar

“…Diabetic mellitus (DM) is characterized by hyperglycaemia and defective macromolecular metabolism, arising from insulin resistance or lack of insulin…”
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Leri: A web-server for identifying protein functional networks from evolutionary couplings by Cheung, Ngaam J., John Peter, Arun T., Kornmann, Benoit

“…[Display omitted] •Identify the evolutionary signatures (termed “residue communities”) from protein sequences.•The identified residue communities specify the…”
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Dissection of Minimal Sequence Requirements for Rhoptry Membrane Targeting in the Malaria Parasite by Cabrera, Ana, Herrmann, Susann, Warszta, Dominik, Santos, Joana M., John Peter, Arun T., Kono, Maya, Debrouver, Sandra, Jacobs, Thomas, Spielmann, Tobias, Ungermann, Christian, Soldati‐Favre, Dominique, Gilberger, Tim W.

“…Rhoptries are specialized secretory organelles characteristic of single cell organisms belonging to the clade Apicomplexa. These organelles play a key role in…”
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Composite Grip Strength as a Marker of Outcome in Patients Surgically Treated for Degenerative Cervical Myelopathy by Paul, Arun John, Amritanand, Rohit, Margabandhu, Prabakaran, Karuppusami, Reka, David, Kenny Samuel, Krishnan, Venkatesh

“…Study Design: Retrospective case series.Purpose: This study aimed to examine the efficacy of composite grip strength as a marker of surgical outcome in…”
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Utilization of PET/CT Scan in Head and Neck Carcinoma: A Tertiary Care Hospital Experience by Chugh, Rajeev, Gupta, D. K., Patel, Bhaumik, John, Arun Ravi, Vashisth, Rekha, Goyal, Sunil

“…Objective PET/CT scan has been increasingly used in assessment of Head and Neck cancer prior to treatment for evaluation and for surveillance. In this study we…”
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Analysis of DHHC Acyltransferases Implies Overlapping Substrate Specificity and a Two-Step Reaction Mechanism by Hou, Haitong, John Peter, Arun T, Meiringer, Christoph, Subramanian, Kanagaraj, Ungermann, Christian

“…Asp-His-His-Cys (DHHC) cysteine-rich domain (CRD) acyltransferases are polytopic transmembrane proteins that are found along the endomembrane system of…”
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F-18 fluorodeoxyglucose positron emission tomography/computed tomography in conjunctival melanoma with recurrence by Jain, Anurag, John, Arun Ravi, Kishore, Braj, Vishnoi, M G, Pandit, Aniruddha G, Sharma, Amit, Jaimini, Abhinav, Jain, Mayuri, Singh, Anirudh

“…Ocular melanoma is classified under the category of noncutaneous melanomas. Noncutaneous melanomas are relatively rare. Ocular melanoma commonly arises from…”
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