Search Results - "Johansson, Pia"
-
1
Transposable Elements: A Common Feature of Neurodevelopmental and Neurodegenerative Disorders
Published in Trends in genetics (01-08-2020)“…The etiology of most neurological disorders is poorly understood and current treatments are largely ineffective. New ideas and concepts are therefore vitally…”
Get full text
Journal Article -
2
The choroid plexuses and their impact on developmental neurogenesis
Published in Frontiers in neuroscience (24-10-2014)“…During brain development the neural stem cells are regulated by both intrinsic and extrinsic sources. One site of origin of extrinsic regulation is the…”
Get full text
Journal Article -
3
Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog
Published in Cell stem cell (04-04-2013)“…As a result of brain injury, astrocytes become activated and start to proliferate in the vicinity of the injury site. Recently, we had demonstrated that these…”
Get full text
Journal Article -
4
The centrosome protein AKNA regulates neurogenesis via microtubule organization
Published in Nature (London) (01-03-2019)“…The expansion of brain size is accompanied by a relative enlargement of the subventricular zone during development. Epithelial-like neural stem cells divide in…”
Get full text
Journal Article Web Resource -
5
The transcription factor Otx2 regulates choroid plexus development and function
Published in Development (Cambridge) (01-03-2013)“…The choroid plexuses (ChPs) are the main regulators of cerebrospinal fluid (CSF) composition and thereby also control the composition of a principal source of…”
Get full text
Journal Article -
6
Bacterial colonisation during regular daily use of a power-driven water flosser and risk for cross-contamination. Can it be prevented?
Published in Clinical oral investigations (01-02-2022)“…Objective To assess whether bacterial colonisation in a power-driven water flosser can be prevented. Materials and methods Twenty-four patients undergoing…”
Get full text
Journal Article -
7
The rights and wrongs of blood-brain barrier permeability studies: a walk through 100 years of history
Published in Frontiers in neuroscience (16-12-2014)“…Careful examination of relevant literature shows that many of the most cherished concepts of the blood-brain barrier are incorrect. These include an almost…”
Get full text
Journal Article -
8
Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease
Published in Nature structural & molecular biology (01-10-2024)“…SVA (SINE (short interspersed nuclear element)–VNTR (variable number of tandem repeats)– Alu ) retrotransposons remain active in humans and contribute to…”
Get full text
Journal Article -
9
Activation of endogenous retroviruses during brain development causes an inflammatory response
Published in The EMBO journal (03-05-2021)“…Endogenous retroviruses (ERVs) make up a large fraction of mammalian genomes and are thought to contribute to human disease, including brain disorders. In the…”
Get full text
Journal Article -
10
Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease
Published in Brain (London, England : 1878) (14-09-2022)“…Abstract Huntington's disease is a neurodegenerative disorder caused by CAG expansions in the huntingtin (HTT) gene. Modelling Huntington's disease is…”
Get full text
Journal Article -
11
Spatio-temporal progression of grey and white matter damage following contusion injury in rat spinal cord
Published in PloS one (09-08-2010)“…Cellular mechanisms of secondary damage progression following spinal cord injury remain unclear. We have studied the extent of tissue damage from 15 min to 10…”
Get full text
Journal Article -
12
A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development
Published in Cell stem cell (06-01-2022)“…The human forebrain has expanded in size and complexity compared to chimpanzees despite limited changes in protein-coding genes, suggesting that gene…”
Get full text
Journal Article -
13
Do you get what you see? The illicit doping market in Denmark—An analysis of performance and image enhancing drugs seized by the police over a 1‐year period
Published in Drug testing and analysis (01-06-2023)“…This study examines doping products seized by the police in three regional police districts in Denmark from December 2019 to December 2020. The products, often…”
Get full text
Journal Article -
14
Patients' opinion on the use of 2 generations of power‐driven water flossers and their impact on gingival inflammation
Published in Clinical and experimental dental research (01-12-2021)“…Objectives To assess patients' opinion on the use of 2 generations of power‐driven water flossers and their impact on gingival inflammation. Material & Methods…”
Get full text
Journal Article -
15
blood-CSF barrier explained: when development is not immaturity
Published in BioEssays (01-03-2008)“…It is often suggested that during development the brain barriers are immature. This argument stems from teleological interpretations and experimental…”
Get full text
Journal Article -
16
HPV self-sampling versus healthcare provider collection on the effect of cervical cancer screening uptake and costs in LMIC: a systematic review and meta-analysis
Published in Systematic reviews (22-06-2023)“…Cervical cancer is a major global health issue, with 89% of cases occurring in low- and middle-income countries (LMICs). Human papillomavirus (HPV)…”
Get full text
Journal Article -
17
Efflux mechanisms at the developing brain barriers: ABC-transporters in the fetal and postnatal rat
Published in Toxicology letters (01-08-2010)“…Proteins of the ATP-binding cassette (ABC) family, present at the blood–brain barrier interfaces, have been shown to reduce the entry of compounds from blood…”
Get full text
Journal Article -
18
Stem cells niches during development — lessons from the cerebral cortex
Published in Current opinion in neurobiology (01-08-2010)“…Adult stem cells are typically dependent on their specific niche environment, here we discuss to which extent this is applicable in the embryonic cortex…”
Get full text
Journal Article -
19
Bacterial colonization of a power‐driven water flosser during regular use. A proof‐of‐principle study
Published in Clinical and experimental dental research (01-10-2021)“…Objectives The present proof‐of‐principle study assessed whether daily use of a power‐driven water flosser (Sonicare AirFloss; SAF) leads to bacterial…”
Get full text
Journal Article -
20
LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
Published in Science advances (03-11-2023)“…The genetic mechanisms underlying the expansion in size and complexity of the human brain remain poorly understood. Long interspersed nuclear element-1 (L1)…”
Get full text
Journal Article