Search Results - "Johansson, N. G."

Retention of prefabricated and individually cast root canal posts in vitro by Hedlund, S -O, Johansson, N G, Sjögren, G

“…The aim of the study was to evaluate the retention of prefabricated root canal posts made of a variety of materials that have recently been introduced into…”
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Urea−PETT Compounds as a New Class of HIV-1 Reverse Transcriptase Inhibitors. 3. Synthesis and Further Structure−Activity Relationship Studies of PETT Analogues by Högberg, Marita, Sahlberg, Christer, Engelhardt, Per, Noréen, Rolf, Kangasmetsä, Jussi, Johansson, Nils Gunnar, Öberg, Bo, Vrang, Lotta, Zhang, Hong, Sahlberg, Britt-Louise, Unge, Torsten, Lövgren, Seved, Fridborg, Kerstin, Bäckbro, Kristina

“…The further development of allosteric HIV-1 RT inhibitors in the urea analogue series of PETT (phenylethylthiazolylthiourea) derivatives is described here. The…”
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A retrospective study of pre-fabricated carbon fibre root canal posts by Hedlund, S.-O., Johansson, N. G., Sjögren, G.

“…summary  Although pre‐fabricated carbon fibre posts have been used during the past decade clinical evaluations of the technique are still few. Using dental…”
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Prevention of simian immunodeficiency virus, SIVsm, or HIV-2 infection in cynomolgus monkeys by pre- and postexposure administration of BEA-005 by BÖTTIGER, D, JOHANSSON, N.-G, SAMUELSSON, B, ZHANG, H, PUTKONEN, P, VRANG, L, ÖBERG, B

“…To study the possibilities and limitations of postexposure treatment to prevent the establishment of infection after accidental exposure to HIV. The effect of…”
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Structure-activity relationships for phosphorylation of nucleoside analogs to monophosphates by nucleoside kinases by Johansson, N G, Eriksson, S

“…The mammalian deoxyribonucleoside kinases thymidine kinase 1 and 2, deoxycytidine kinase and deoxyguanosine kinase phosphorylate deoxyribonucleosides and…”
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The PETT series, a new class of potent nonnucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase by AHGREN, C, BACKRO, K, JOHANSSON, N. G, JORDAN, C. L, KASHER, J. S, KINNICK, M. D, LIND, P, LOPEZ, C, MORIN, J. M, MUESING, M. A, NOREEN, R, OBERG, B, BELL, F. W, PAGET, C. J, PALKOWITZ, J. A, PARRISH, C. A, PRANC, P, RIPPY, M. K, RYDERGARD, C, SAHLBERG, C, SWANSON, S, TERNANSKY, R. J, UNGE, T, CANTRELL, A. S, VASILEFF, R. T, VRANG, L, WEST, S. J, ZHANG, H, ZHOU, X.-X, CLEMENS, M, COLACINO, J. M, DEETER, J. B, ENGELHARDT, J. A, HOGBERG, M, JASKUNAS, S. R

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Mode of action, toxicity, pharmacokinetics, and efficacy of some new antiherpesvirus guanosine analogs related to buciclovir by LARSSON, A, STENBERG, K, ERICSON, A.-C, HAGLUND, U, YISAK, W.-A, JOHANSSON, N. G, OBERG, B, DATEMA, R

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Acyclonucleoside analogue inhibitors of mammalian purine nucleoside phosphorylase by Bzowska, A, Kulikowska, E, Shugar, D, Chen, B Y, Lindborg, B, Johansson, N G

“…A series of about 60 purine acyclonucleosides, most with guanine as the aglycone and a 4-carbon chain as the acyclic moiety, was examined for ability to…”
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Phenethylthiazolethiourea (PETT) Compounds, a New Class of HIV-1 Reverse Transcriptase Inhibitors. 1. Synthesis and Basic Structure-Activity Relationship Studies of PETT Analogs by Bell, Frank W, Cantrell, Amanda S, Hoegberg, Marita, Jaskunas, S. Richard, Johansson, Nils Gunnar, Jordan, Christopher L, Kinnick, Michael D, Lind, Peter, Morin, John M

“…A novel series of potent specific HIV-1 inhibitory compounds is described. The lead compound in the series, N-(2-phenethyl)-N'-(2-thiazolyl)thiourea (1),…”
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Antiherpetic activity and mechanism of action of 9-(4-hydroxybutyl)guanine by Larsson, A, Alenius, S, Johansson, N G, Oberg, B

“…9-(4-Hydroxybutyl)guanine was synthesized and tested for antiherpes activity. In cell cultures, different strains of herpes simplex virus type 1 (HSV-1) and…”
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Comparison of the substrate specificities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs by Eriksson, S, Kierdaszuk, B, Munch-Petersen, B, Oberg, B, Johansson, N G

“…Deoxynucleoside kinases are required for the 5'-phosphorylation of deoxynucleoside analogs used in chemotherapy. Cytoplasmic thymidine kinase (TK1),…”
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9-(3,4-dihydroxybutyl)guanine, a new inhibitor of herpesvirus multiplication by Larsson, A, Oberg, B, Alenius, S, Hagberg, C E, Johansson, N G, Lindborg, B, Stening, G

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Antiherpes effects and pharmacokinetic properties of 9-(4-hydroxybutyl) guanine and the (R) and (S) enantiomers of 9-(3,4-dihydroxybutyl)guanine by ERICSON, A.-C, LARSSON, A, AOKI, F. Y, YISAK, W.-A, JOHANSSON, N.-G, OBERG, B, DATEMA, R

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An analysis of the inhibition of replication of HIV and MuLV by some 3'-blocked pyrimidine analogs by Bazin, H, Chattopadhyaya, J, Datema, R, Ericson, A C, Gilljam, G, Johansson, N G, Hansen, J, Koshida, R, Moelling, K, Oberg, B

“…Some 3'-blocked pyrimidine analogs were synthesized and tested as inhibitors of replication of human immunodeficiency virus (HIV) and Moloney-murine leukemia…”
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The relative merits and drawbacks of new nucleoside analogues with clinical potential by Oberg, B, Johansson, N G

“…A large number of nucleoside analogues have been found to have antiviral activity, mainly against herpesviruses. The involvement of cellular as well as viral…”
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Trisodium Phosphonoformate, a New Antiviral Compound by Helgstrand, E., Eriksson, B., Johansson, N. G., Lannerö, B., Larsson, A., Misiorny, A., Norén, J. O., Sjöberg, B., Stenberg, K., Stening, G., Stridh, S., Öberg, B., Alenius, S., Philipson, L.

“…Trisodium phosphonoformate selectively inhibits cell-free DNA polymerase activity induced by herpesvirus. The new inhibitor has an antiviral effect on herpes…”
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Phenethylthiazolylthiourea (PETT) Compounds as a New Class of HIV-1 Reverse Transcriptase Inhibitors. 2. Synthesis and Further Structure−Activity Relationship Studies of PETT Analogs by Cantrell, Amanda S, Engelhardt, Per, Högberg, Marita, Jaskunas, S. Richard, Johansson, Nils Gunnar, Jordan, Christopher L, Kangasmetsä, Jussi, Kinnick, Michael D, Lind, Peter, Morin, John M, Muesing, M. A, Noreén, Rolf, Öberg, Bo, Pranc, Paul, Sahlberg, Christer, Ternansky, Robert J, Vasileff, Robert T, Vrang, Lotta, West, Sarah J, Zhang, Hong

“…Phenylethylthiazolylthiourea (PETT) derivatives have been identified as a new series of non-nucleoside inhibitors of HIV-1 RT. Structure−activity relationship…”
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Inhibition of Influenza Virus Ribonucleic Acid Polymerase by Ribavirin Triphosphate by Eriksson, B, Helgstrand, E, Johansson, N G, Larsson, A, Misiorny, A, Norén, J O, Philipson, L, Stenberg, K, Stening, G, Stridh, S, Oberg, B

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Inhibition of HIV-1 reverse transcriptase by 5'-triphosphates of 5-substituted uridine analogs by Tao, P Z, Johansson, N G, Stening, G, Oberg, B, Datema, R

“…The 5'-triphosphates of some 5-substituted 2'-deoxyuridine analogs were investigated for their effects on purified recombinant reverse transcriptase of human…”
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Inhibition of human hepatitis B virus DNA polymerase and duck hepatitis B virus DNA polymerase by triphosphates of thymidine analogs and pharmacokinetic properties of the corresponding nucleosides by Tao, P Z, Löfgren, B, Lake-Bakaar, D, Johansson, N G, Datema, R, Oberg, B

“…Replication of hepadnaviruses involves a viral DNA polymerase containing both a DNA-dependent and an RNA dependent activity. This polymerase is a potential…”
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