Search Results - "Johansson, Marcus J O"
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SSD1 suppresses phenotypes induced by the lack of Elongator-dependent tRNA modifications
Published in PLoS genetics (29-08-2019)“…The Elongator complex promotes formation of 5-methoxycarbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) side-chains on uridines at the wobble position of…”
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Eukaryotic Wobble Uridine Modifications Promote a Functionally Redundant Decoding System
Published in Molecular and Cellular Biology (01-05-2008)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Association of yeast Upf1p with direct substrates of the NMD pathway
Published in Proceedings of the National Academy of Sciences - PNAS (26-12-2007)“…Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that detects and degrades transcripts containing premature translation termination codons. Gene…”
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Structure-functional characterization of Lactococcus AbiA phage defense system
Published in Nucleic acids research (08-05-2024)“…Bacterial reverse transcriptases (RTs) are a large and diverse enzyme family. AbiA, AbiK and Abi-P2 are abortive infection system (Abi) RTs that mediate…”
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The ABCF ATPase New1 resolves translation termination defects associated with specific tRNAArg and tRNALys isoacceptors in the P site
Published in Nucleic acids research (01-09-2024)“…The efficiency of translation termination is determined by the nature of the stop codon as well as its context. In eukaryotes, recognition of the A-site stop…”
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Ribosome profiling analysis of eEF3-depleted Saccharomyces cerevisiae
Published in Scientific reports (28-02-2019)“…In addition to the standard set of translation factors common in eukaryotic organisms, protein synthesis in the yeast Saccharomyces cerevisiae requires an ABCF…”
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SSD1 modifies phenotypes of Elongator mutants
Published in Current genetics (01-06-2020)“…The translational decoding properties of tRNAs are influenced by post-transcriptional modification of nucleosides in their anticodon region. The Elongator…”
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The pre-mRNA retention and splicing complex controls tRNA maturation by promoting TAN1 expression
Published in Nucleic acids research (01-06-2013)“…The conserved pre-mRNA retention and splicing (RES) complex, which in yeast consists of Bud13p, Snu17p and Pml1p, is thought to promote nuclear retention of…”
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Elevated Levels of Two tRNA Species Bypass the Requirement for Elongator Complex in Transcription and Exocytosis
Published in Molecular cell (06-10-2006)“…The Saccharomyces cerevisiae Elongator complex consisting of the six Elp1–Elp6 proteins has been proposed to participate in three distinct cellular processes:…”
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10
Nonsense-mediated mRNA decay maintains translational fidelity by limiting magnesium uptake
Published in Genes & development (15-07-2010)“…Inactivation of the yeast nonsense-mediated mRNA decay (NMD) pathway stabilizes nonsense mRNAs and promotes readthrough of premature translation termination…”
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Elimination of Ribosome Inactivating Factors Improves the Efficiency of Bacillus subtilis and Saccharomyces cerevisiae Cell-Free Translation Systems
Published in Frontiers in microbiology (2018)“…Cell-free translation systems based on cellular lysates optimized for protein synthesis have multiple applications both in basic and applied science, ranging…”
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Elongator—a tRNA modifying complex that promotes efficient translational decoding
Published in Biochimica et biophysica acta. Gene regulatory mechanisms (01-04-2018)“…Naturally occurring modifications of the nucleosides in the anticodon region of tRNAs influence their translational decoding properties. Uridines present at…”
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CCR3 deficiency is associated with increased osteoclast activity and reduced cortical bone volume in adult male mice
Published in The Journal of biological chemistry (01-01-2021)“…Increasing evidence emphasizes the importance of chemokines and chemokine receptors as regulators of bone remodeling. The C–C chemokine receptor 3 (CCR3) is…”
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14
The structural basis of hyperpromiscuity in a core combinatorial network of type II toxin-antitoxin and related phage defense systems
Published in Proceedings of the National Academy of Sciences - PNAS (15-08-2023)“…Toxin-antitoxin (TA) systems are a large group of small genetic modules found in prokaryotes and their mobile genetic elements. Type II TAs are encoded as…”
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A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling
Published in Nucleic acids research (19-09-2019)“…Translation is controlled by numerous accessory proteins and translation factors. In the yeast Saccharomyces cerevisiae, translation elongation requires an…”
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Mechanism of phage sensing and restriction by toxin-antitoxin-chaperone systems
Published in Cell host & microbe (10-07-2024)“…Toxin-antitoxins (TAs) are prokaryotic two-gene systems composed of a toxin neutralized by an antitoxin. Toxin-antitoxin-chaperone (TAC) systems additionally…”
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Determining if an mRNA is a Substrate of Nonsense-Mediated mRNA Decay in Saccharomyces cerevisiae
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2017)“…Nonsense-mediated mRNA decay (NMD) is a conserved eukaryotic quality control mechanism which triggers decay of mRNAs harboring premature translation…”
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The pre-mRNA retention and splicing complex controls expression of the Mediator subunit Med20
Published in RNA biology (03-10-2017)“…The heterotrimeric pre-mRNA retention and splicing (RES) complex, consisting of Bud13p, Snu17p and Pml1p, promotes splicing and nuclear retention of a subset…”
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Identification of factors that promote biogenesis of tRNACGASer
Published in RNA biology (01-01-2018)“…A wide variety of factors are required for the conversion of pre-tRNA molecules into the mature tRNAs that function in translation. To identify factors…”
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An early step in wobble uridine tRNA modification requires the Elongator complex
Published in RNA (Cambridge) (01-04-2005)“…Elongator has been reported to be a histone acetyltransferase complex involved in elongation of RNA polymerase II transcription. In Saccharomyces cerevisiae,…”
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