Search Results - "Johansson, Hanna"

Perinatal exposure to known endocrine disrupters alters ovarian development and systemic steroid hormone profile in rats by Boberg, Julie, Johansson, Hanna K.L., Franssen, Delphine, Cramer, Johannah H., Usai, Diana, Pedersen, Mikael, Parent, Anne-Simone, Svingen, Terje

“…Disrupted ovarian development induced by chemical exposure may impair fertility later in life. Since androgens are essential for early ovarian development, we…”
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Classical toxicity endpoints in female rats are insensitive to the human endocrine disruptors diethylstilbestrol and ketoconazole by Johansson, Hanna K.L., Christiansen, Sofie, Draskau, Monica Kam, Svingen, Terje, Boberg, Julie

“…•Current endpoints used for female reproductive toxicity are not sensitive enough.•New and improved test methods for female reproductive toxicity are…”
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Grouping of endocrine disrupting chemicals for mixture risk assessment – Evidence from a rat study by Christiansen, Sofie, Axelstad, Marta, Scholze, Martin, Johansson, Hanna K.L., Hass, Ulla, Mandrup, Karen, Frandsen, Henrik Lauritz, Frederiksen, Hanne, Isling, Louise Krag, Boberg, Julie

“…•Grouping of chemicals for risk assessment should be based on shared health outcomes.•Adverse Outcome Pathway can provide important guidance to mixture risk…”
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Metabolic profiling reveals metabolic shifts in Arabidopsis plants grown under different light conditions by JÄNKÄNPÄÄ, HANNA JOHANSSON, MISHRA, YOGESH, SCHRÖDER, WOLFGANG P., JANSSON, STEFAN

“…ABSTRACT Plants have tremendous capacity to adjust their morphology, physiology and metabolism in response to changes in growing conditions. Thus, analysis…”
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Transcriptional profiling of the developing rat ovary following intrauterine exposure to the endocrine disruptors diethylstilbestrol and ketoconazole by Kugathas, Indusha, Johansson, Hanna K. L., Chan Sock Peng, Edith, Toupin, Maryne, Evrard, Bertrand, Darde, Thomas A., Boberg, Julie, Draskau, Monica K., Rolland, Antoine D., Mazaud-Guittot, Séverine, Chalmel, Frédéric, Svingen, Terje

“…Exposure to endocrine-disrupting chemicals (EDCs) during development may cause reproductive disorders in women. Although female reproductive endpoints are…”
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Using assessment criteria for pesticides to evaluate the endocrine disrupting potential of non-pesticide chemicals: Case butylparaben by Boberg, Julie, Johansson, Hanna K.L., Axelstad, Marta, Olsen, Gustav P.M., Johansen, Mathias, Holmboe, Stine A., Andersson, Anna-Maria, Svingen, Terje

“…•In-depth analysis identifies butylparaben as an endocrine disruptor.•Butylparaben shows estrogenic MoA and adverse effect on sperm in rodent…”
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Exposure to the pesticides linuron, dimethomorph and imazalil alters steroid hormone profiles and gene expression in developing rat ovaries by Boberg, Julie, Johansson, Hanna K.L., Franssen, Delphine, Draskau, Monica Kam, Christiansen, Sofie, Cramer, Johannah, Pedersen, Mikael, Parent, Anne-Simone, Svingen, Terje

“…Inhibition of androgen signaling during critical stages of ovary development can disrupt folliculogenesis with potential consequences for reproductive function…”
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Organophosphate ester flame retardants have antiandrogenic potential and affect other endocrine related endpoints in vitro and in silico by Rosenmai, Anna Kjerstine, Winge, Sofia Boeg, Möller, Morlin, Lundqvist, Johan, Wedebye, Eva Bay, Nikolov, Nikolai Georgiev, Lilith Johansson, Hanna Katarina, Vinggaard, Anne Marie

“…Organophosphate ester flame retardants (OPFRs) are used to prevent ignition and spreading of fire. They are present in various human matrices suggesting adult,…”
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Minor changes to circulating steroid hormones in female rats after perinatal exposure to diethylstilbestrol or ketoconazole by Vazakidou, Paraskevi, Bouftas, Nora, Heinzelmann, Manuel, Johansson, Hanna K.L., Svingen, Terje, Leonards, Pim E.G., van Duursen, Majorie B.M.

“…Current chemical test strategies lack sensitive markers for detecting female reproductive toxicity caused by endocrine disrupting chemicals (EDCs). In search…”
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Arabidopsis plants grown in the field and climate chambers significantly differ in leaf morphology and photosystem components by Mishra, Yogesh, Jänkänpää, Hanna Johansson, Kiss, Anett Z, Funk, Christiane, Schröder, Wolfgang P, Jansson, Stefan

“…Plants exhibit phenotypic plasticity and respond to differences in environmental conditions by acclimation. We have systematically compared leaves of…”
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Fitness analyses of Arabidopsis thaliana mutants depleted of FtsH metalloproteases and characterization of three FtsH6 deletion mutants exposed to high light stress, senescence and chilling by Wagner, Raik, Aigner, Harald, Pružinská, Adriana, Jänkänpää, Hanna Johansson, Jansson, Stefan, Funk, Christiane

“…Darwinian fitness analyses were performed, comparing single ftsh mutants with wild-type Arabidopsis thaliana plants grown under controlled laboratory…”
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Quantitative analysis of ovarian surface photographs as a tool for assessment of chemical effects on folliculogenesis and ovulation in rats by Li, Tianyi, Boberg, Julie, Johansson, Hanna K.L., Di Nisio, Valentina, Christiansen, Sofie, Svingen, Terje, Damdimopoulou, Pauliina

“…Female reproductive toxicity assessments rely on histological evaluation of ovaries by hematoxylin & eosin (H&E)-stained cross-sections. This is…”
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Presence of High-Risk HPV mRNA in Relation to Future High-Grade Lesions among High-Risk HPV DNA Positive Women with Minor Cytological Abnormalities by Johansson, Hanna, Bjelkenkrantz, Kaj, Darlin, Lotten, Dilllner, Joakim, Forslund, Ola

“…Continuous expression of E6- and E7-oncogenes of high-risk human papillomavirus (HPV) types is necessary for the development and maintenance of the dysplastic…”
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Low temperatures enhance the toxicity of copper and cadmium to Enchytraeus crypticus through different mechanisms by Cedergreen, Nina, Nørhave, Nils Jakob, Nielsen, Kristoffer, Johansson, Hanna K.L., Marcussen, Helle, Svendsen, Claus, Spurgeon, David J

“…Knowledge about how toxicity changes with temperature is important for determining the extent of safety factors required when extrapolating from standard…”
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Metagenomic sequencing of “HPV-negative” condylomas detects novel putative HPV types by Johansson, Hanna, Bzhalava, Davit, Ekström, Johanna, Hultin, Emilie, Dillner, Joakim, Forslund, Ola

“…Abstract Condylomas are caused by human papillomavirus (HPV), but may in rare cases be “negative for HPV” by PCR. Metagenomic sequencing can be used for an…”
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Hedgehog signal disruption, gonadal dysgenesis and reproductive disorders: Is there a link to endocrine disrupting chemicals? by Johansson, Hanna K.L., Svingen, Terje

“…[Display omitted] •Hedgehog signaling is required for reproductive development.•Exposure to environmental chemicals can disrupt Hedgehog signaling and cause…”
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Perinatal exposure to the fungicide ketoconazole alters hypothalamic control of puberty in female rats by Franssen, Delphine, Johansson, Hanna K L, Lopez-Rodriguez, David, Lavergne, Arnaud, Terwagne, Quentin, Boberg, Julie, Christiansen, Sofie, Svingen, Terje, Parent, Anne-Simone

“…Estrogenic endocrine disrupting chemicals (EDCs) such as diethylstilbestrol (DES) are known to alter the timing of puberty onset and reproductive function in…”
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Putative adverse outcome pathways for female reproductive disorders to improve testing and regulation of chemicals by Johansson, Hanna K. L., Damdimopoulou, Pauliina, van Duursen, Majorie B. M., Boberg, Julie, Franssen, Delphine, de Cock, Marijke, Jääger, Kersti, Wagner, Magdalena, Velthut-Meikas, Agne, Xie, Yuling, Connolly, Lisa, Lelandais, Pauline, Mazaud-Guittot, Severine, Salumets, Andres, Draskau, Monica Kam, Filis, Panagiotis, Fowler, Paul A., Christiansen, Sofie, Parent, Anne-Simone, Svingen, Terje

“…Modern living challenges female reproductive health. We are witnessing a rise in reproductive disorders and drop in birth rates across the world. The reasons…”
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Comparison of female rat reproductive effects of pubertal versus adult exposure to known endocrine disruptors by Boberg, Julie, Li, Tianyi, Christiansen, Sofie, Draskau, Monica K., Damdimopoulou, Pauliina, Svingen, Terje, Johansson, Hanna K. L.

“…A prevailing challenge when testing chemicals for their potential to cause female reproductive toxicity is the lack of appropriate toxicological test methods…”
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The Swedish King's Parkinson's disease Pain Scale: Validation and pain prevalence in persons with mild-moderate severity Parkinson's disease by Joseph, Conran, Johansson, Hanna, Leavy, Breiffni, Franzen, Erika

“…To examine convergent and divergent validity of the King's Parkinson's disease Pain Scale - Swedish translated version, and to determine the prevalence of pain…”
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