Search Results - "Johansen, Matt D."

Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus by Johansen, Matt D., Herrmann, Jean-Louis, Kremer, Laurent

“…Infections caused by non-tuberculous mycobacteria (NTM) are increasing globally and are notoriously difficult to treat due to intrinsic resistance of these…”
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The Role of Macrophages During Zebrafish Injury and Tissue Regeneration Under Infectious and Non-Infectious Conditions by Bohaud, Candice, Johansen, Matt D, Jorgensen, Christian, Ipseiz, Natacha, Kremer, Laurent, Djouad, Farida

“…The future of regenerative medicine relies on our understanding of the mechanistic processes that underlie tissue regeneration, highlighting the need for…”
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Editorial: Recent advancements in mycobacterial diseases research by Johansen, Matt D, Pasipanodya, Jotam G, Subbian, Selvakumar, Venketaraman, Vishwanath

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Rough and smooth variants of Mycobacterium abscessus are differentially controlled by host immunity during chronic infection of adult zebrafish by Kam, Julia Y., Hortle, Elinor, Krogman, Elizabeth, Warner, Sherridan E., Wright, Kathryn, Luo, Kaiming, Cheng, Tina, Manuneedhi Cholan, Pradeep, Kikuchi, Kazu, Triccas, James A., Britton, Warwick J., Johansen, Matt D., Kremer, Laurent, Oehlers, Stefan H.

“…Prevalence of Mycobacterium abscessus infections is increasing in patients with respiratory comorbidities. After initial colonisation, M. abscessus smooth…”
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CFTR Depletion Confers Hypersusceptibility to Mycobacterium fortuitum in a Zebrafish Model by Johansen, Matt D, Kremer, Laurent

“…The complex comprises several closely related species, causing pulmonary and extra-pulmonary infections. However, there is very limited knowledge about the…”
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Nanoparticle Delivery Platforms for RNAi Therapeutics Targeting COVID-19 Disease in the Respiratory Tract by Zhang, Yuan, Almazi, Juhura G, Ong, Hui Xin, Johansen, Matt D, Ledger, Scott, Traini, Daniela, Hansbro, Philip M, Kelleher, Anthony D, Ahlenstiel, Chantelle L

“…Since December 2019, a pandemic of COVID-19 disease, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread across the…”
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The Role of Macrophages During Mammalian Tissue Remodeling and Regeneration Under Infectious and Non-Infectious Conditions by Bohaud, Candice, Johansen, Matt D., Jorgensen, Christian, Kremer, Laurent, Ipseiz, Natacha, Djouad, Farida

“…Several infectious pathologies in humans, such as tuberculosis or SARS-CoV-2, are responsible for tissue or lung damage, requiring regeneration. The…”
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Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria by Santucci, Pierre, Johansen, Matt D., Point, Vanessa, Poncin, Isabelle, Viljoen, Albertus, Cavalier, Jean-François, Kremer, Laurent, Canaan, Stéphane

“…Mycobacteria share with other actinomycetes the ability to produce large quantities of triacylglycerol (TAG), which accumulate as intracytoplasmic lipid…”
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Mycobacteriophage-antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus by Johansen, Matt D, Alcaraz, Matthéo, Dedrick, Rebekah M, Roquet-Banères, Françoise, Hamela, Claire, Hatfull, Graham F, Kremer, Laurent

“…Infection by multidrug-resistant Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF) patients, leaving clinicians with few therapeutic…”
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Virulence Mechanisms of Mycobacterium abscessus : Current Knowledge and Implications for Vaccine Design by Ferrell, Kia C, Johansen, Matt D, Triccas, James A, Counoupas, Claudio

“…is a member of the non-tuberculous mycobacteria (NTM) group, responsible for chronic infections in individuals with cystic fibrosis (CF) or those otherwise…”
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Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice by Ashhurst, Anneliese S., Johansen, Matt D., Maxwell, Joshua W. C., Stockdale, Skye, Ashley, Caroline L., Aggarwal, Anupriya, Siddiquee, Rezwan, Miemczyk, Stefan, Nguyen, Duc H., Mackay, Joel P., Counoupas, Claudio, Byrne, Scott N., Turville, Stuart, Steain, Megan, Triccas, James A., Hansbro, Philip M., Payne, Richard J., Britton, Warwick J.

“…Current vaccines against SARS-CoV-2 substantially reduce mortality, but protection against infection is less effective. Enhancing immunity in the respiratory…”
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Thrombocyte Inhibition Restores Protective Immunity to Mycobacterial Infection in Zebrafish by Hortle, Elinor, Johnson, Khelsey E, Johansen, Matt D, Nguyen, Tuong, Shavit, Jordan A, Britton, Warwick J, Tobin, David M, Oehlers, Stefan H

“…Infection-induced thrombocytosis is a clinically important complication of tuberculosis infection. Recent studies have highlighted the utility of aspirin as a…”
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The ESX-4 substrates, EsxU and EsxT, modulate Mycobacterium abscessus fitness by Lagune, Marion, Le Moigne, Vincent, Johansen, Matt D, Vásquez Sotomayor, Flor, Daher, Wassim, Petit, Cécile, Cosentino, Gina, Paulowski, Laura, Gutsmann, Thomas, Wilmanns, Matthias, Maurer, Florian P, Herrmann, Jean-Louis, Girard-Misguich, Fabienne, Kremer, Laurent

“…ESX type VII secretion systems are complex secretion machineries spanning across the mycobacterial membrane and play an important role in pathogenicity,…”
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Mycobacterium marinum infection drives foam cell differentiation in zebrafish infection models by Johansen, Matt D., Kasparian, Joshua A., Hortle, Elinor, Britton, Warwick J., Purdie, Auriol C., Oehlers, Stefan H.

“…Host lipid metabolism is an important target for subversion by pathogenic mycobacteria such as Mycobacterium tuberculosis. The appearance of foam cells within…”
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Exploring Macrophage-Dependent Wound Regeneration During Mycobacterial Infection in Zebrafish by Bohaud, Candice, Johansen, Matt D, Varga, Béla, Contreras-Lopez, Rafael, Barthelaix, Audrey, Hamela, Claire, Sapède, Dora, Cloitre, Thierry, Gergely, Csilla, Jorgensen, Christian, Kremer, Laurent, Djouad, Farida

“…The molecular and cellular mechanisms associated with tissue degradation or regeneration in an infectious context are poorly defined. Herein, we explored the…”
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Cellular and molecular features of COVID-19 associated ARDS: therapeutic relevance by Scaramuzzo, Gaetano, Nucera, Francesco, Asmundo, Alessio, Messina, Roberto, Mari, Matilde, Montanaro, Federica, Johansen, Matt D, Monaco, Francesco, Fadda, Guido, Tuccari, Giovanni, Hansbro, Nicole G, Hansbro, Philip M, Hansel, Trevor T, Adcock, Ian M, David, Antonio, Kirkham, Paul, Caramori, Gaetano, Volta, Carlo Alberto, Spadaro, Savino

“…The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection can be asymptomatic or cause a disease (COVID-19) characterized by different levels…”
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Expression of targets of the RNA-binding protein AUF-1 in human airway epithelium indicates its role in cellular senescence and inflammation by Salvato, Ilaria, Ricciardi, Luca, Dal Col, Jessica, Nigro, Annunziata, Giurato, Giorgio, Memoli, Domenico, Sellitto, Assunta, Lamparelli, Erwin Pavel, Crescenzi, Maria Assunta, Vitale, Monica, Vatrella, Alessandro, Nucera, Francesco, Brun, Paola, Caicci, Federico, Dama, Paola, Stiff, Thomas, Castellano, Leandro, Idrees, Sobia, Johansen, Matt D, Faiz, Alen, Wark, Peter A, Hansbro, Philip M, Adcock, Ian M, Caramori, Gaetano, Stellato, Cristiana

“…The RNA-binding protein AU-rich-element factor-1 (AUF-1) participates to posttranscriptional regulation of genes involved in inflammation and cellular…”
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The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders by Chong, Wai Chin, Shastri, Madhur D, Peterson, Gregory M, Patel, Rahul P, Pathinayake, Prabuddha S, Dua, Kamal, Hansbro, Nicole G, Hsu, Alan C, Wark, Peter A, Shukla, Shakti Dhar, Johansen, Matt D, Schroder, Kate, Hansbro, Philip M

“…Inflammation is the result of a complex network of cellular and molecular interactions and mechanisms that facilitate immune protection against intrinsic and…”
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Analysis of mycobacterial infection-induced changes to host lipid metabolism in a zebrafish infection model reveals a conserved role for LDLR in infection susceptibility by Johansen, Matt D., Hortle, Elinor, Kasparian, Joshua A., Romero, Alejandro, Novoa, Beatriz, Figueras, Antonio, Britton, Warwick J., de Silva, Kumudika, Purdie, Auriol C., Oehlers, Stefan H.

“…Changes to lipid metabolism are well-characterised consequences of human tuberculosis infection but their functional relevance are not clearly elucidated in…”
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Functional Characterization of the N -Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus by Küssau, Tanja, Van Wyk, Niël, Johansen, Matt D, Alsarraf, Husam M A B, Neyret, Aymeric, Hamela, Claire, Sørensen, Kasper K, Thygesen, Mikkel B, Beauvineau, Claire, Kremer, Laurent, Blaise, Mickaël

“…Peptidoglycan (PG) is made of a polymer of disaccharides organized as a three-dimensional mesh-like network connected together by peptidic cross-links. PG is a…”
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