Search Results - "Johansen, Kristen M"
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JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila
Published in Nature communications (25-11-2019)“…In flies, the chromosomal kinase JIL-1 is responsible for most interphase histone H3S10 phosphorylation and has been proposed to protect active chromatin from…”
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Regulation of chromatin structure by histone H3S10 phosphorylation
Published in Chromosome research (01-05-2006)“…The epigenetic phospho-serine 10 modification of histone H3 has been a puzzle due to its association with two apparently opposed chromatin states. It is found…”
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Evidence for a role of spindle matrix formation in cell cycle progression by antibody perturbation
Published in PloS one (28-11-2018)“…In Drosophila it has recently been demonstrated that a spindle matrix in the form of a membrane-less macromolecular assembly embeds the microtubule-based…”
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Spatiotemporal control of mitosis by the conserved spindle matrix protein Megator
Published in The Journal of cell biology (09-03-2009)“…A putative spindle matrix has been hypothesized to mediate chromosome motion, but its existence and functionality remain controversial. In this report, we show…”
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A nuclear-derived proteinaceous matrix embeds the microtubule spindle apparatus during mitosis
Published in Molecular biology of the cell (15-09-2012)“…The concept of a spindle matrix has long been proposed. Whether such a structure exists, however, and what its molecular and structural composition are have…”
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Genome-wide analysis of regulation of gene expression and H3K9me2 distribution by JIL-1 kinase mediated histone H3S10 phosphorylation in Drosophila
Published in Nucleic acids research (01-05-2014)“…In this study we have determined the genome-wide relationship of JIL-1 kinase mediated H3S10 phosphorylation with gene expression and the distribution of the…”
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Digitor/dASCIZ Has Multiple Roles in Drosophila Development
Published in PloS one (18-11-2016)“…In this study we provide evidence that the spindle matrix protein Skeletor in Drosophila interacts with the human ASCIZ (also known as ATMIN and ZNF822)…”
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The JIL-1 histone H3S10 kinase regulates dimethyl H3K9 modifications and heterochromatic spreading in Drosophila
Published in Development (Cambridge) (01-01-2006)“…In this study, we show that a reduction in the levels of the JIL-1 histone H3S10 kinase results in the spreading of the major heterochromatin markers dimethyl…”
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Polytene chromosome squash methods for studying transcription and epigenetic chromatin modification in Drosophila using antibodies
Published in Methods (San Diego, Calif.) (01-08-2009)“…The giant polytene chromosomes from Drosophila third instar larval salivary glands provide an important model system for studying the architectural changes in…”
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Evidence against a role for the JIL-1 kinase in H3S28 phosphorylation and 14-3-3 recruitment to active genes in Drosophila
Published in PloS one (30-04-2013)“…JIL-1 is the major kinase controlling phosphorylation of histone H3S10 and has been demonstrated to function to counteract heterochromatization and gene…”
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Ectopic histone H3S10 phosphorylation causes chromatin structure remodeling in Drosophila
Published in Development (Cambridge) (01-02-2008)“…Histones are subject to numerous post-translational modifications that correlate with the state of higher-order chromatin structure and gene expression…”
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The spindle matrix protein, Chromator, is a novel tubulin binding protein that can interact with both microtubules and free tubulin
Published in PloS one (29-07-2014)“…The chromodomain protein, Chromator, is localized to chromosomes during interphase; however, during cell division together with other nuclear proteins…”
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RNA polymerase II-mediated transcription at active loci does not require histone H3S10 phosphorylation in Drosophila
Published in Development (Cambridge) (01-09-2008)“…JIL-1 is the major kinase controlling the phosphorylation state of histone H3S10 at interphase in Drosophila . In this study, we used three different…”
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14
Phosphorylation of SU(VAR)3-9 by the chromosomal kinase JIL-1
Published in PloS one (06-04-2010)“…The histone methyltransferase SU(VAR)3-9 plays an important role in the formation of heterochromatin within the eukaryotic nucleus. Several studies have shown…”
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Spatiotemporal coordination of Greatwall-Endos-PP2A promotes mitotic progression
Published in The Journal of cell biology (07-06-2021)“…Mitotic entry involves inhibition of protein phosphatase 2A bound to its B55/Tws regulatory subunit (PP2A-B55/Tws), which dephosphorylates substrates of…”
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The COOH-terminal Domain of the JIL-1 Histone H3S10 Kinase Interacts with Histone H3 and Is Required for Correct Targeting to Chromatin
Published in The Journal of biological chemistry (21-11-2008)“…The JIL-1 histone H3S10 kinase in Drosophila localizes specifically to euchromatic interband regions of polytene chromosomes and is enriched 2-fold on the male…”
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H3S10 phosphorylation by the JIL-1 kinase regulates H3K9 dimethylation and gene expression at the white locus in Drosophila
Published in Fly (Austin, Tex.) (01-04-2012)“…The JIL-1 kinase is a multidomain protein that localizes specifically to euchromatin interband regions of polytene chromosomes and is the kinase responsible…”
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Recent Glimpses of the Elusive Spindle Matrix
Published in Cell cycle (Georgetown, Tex.) (01-09-2002)“…A stationary spindle matrix has been proposed on theoretical grounds to help mediate force production at the mitotic spindle. Direct molecular evidence for the…”
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Chromatin structure and the regulation of gene expression: the lessons of PEV in Drosophila
Published in Advances in genetics (2008)“…Position-effect variegation (PEV) was discovered in 1930 in a study of X-ray-induced chromosomal rearrangements. Rearrangements that place euchromatic genes…”
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Do nuclear envelope and intranuclear proteins reorganize during mitosis to form an elastic, hydrogel-like spindle matrix
Published in Chromosome research (01-04-2011)“…The idea of a spindle matrix has long been proposed in order to account for poorly understood features of mitosis. However, its molecular nature and structural…”
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