Search Results - "Johansen, Berit"

Logical and experimental modeling of cytokine and eicosanoid signaling in psoriatic keratinocytes by Tsirvouli, Eirini, Ashcroft, Felicity, Johansen, Berit, Kuiper, Martin

“…Psoriasis is a chronic skin disease, in which immune cells and keratinocytes keep each other in a state of inflammation. It is believed that phospholipase A2…”
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Detection and Differentiation of Breast Cancer Sub-Types using a cPLA2α Activatable Fluorophore by Chiorazzo, Michael G., Tunset, Hanna Maja, Popov, Anatoliy V., Johansen, Berit, Moestue, Siver, Delikatny, E. James

“…Cytosolic phospholipase A2α (cPLA2α) has been shown to be elevated in breast cancer and is a potential biomarker in the differentiation of molecular sub-types…”
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Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells by Mahammad, Nur, Ashcroft, Felicity J, Feuerherm, Astrid J, Elsaadi, Samah, Vandsemb, Esten N, Børset, Magne, Johansen, Berit

“…Cytosolic phospholipase A2α (cPLA2α) is the rate-limiting enzyme in releasing arachidonic acid and biosynthesis of its derivative eicosanoids. Thus, the…”
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Cytosolic Phospholipase A2 Alpha Regulates TLR Signaling and Migration in Metastatic 4T1 Cells by Tunset, Hanna Maja, Feuerherm, Astrid Jullumstrø, Selvik, Linn-Karina Myrland, Johansen, Berit, Moestue, Siver Andreas

“…Metastatic disease is the leading cause of death in breast cancer patients. Disrupting the cancer cell's ability to migrate may be a strategy for hindering…”
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Cytosolic phospholipase A2 regulates TNF-induced production of joint destructive effectors in synoviocytes by Sommerfelt, Randi M, Feuerherm, Astrid J, Jones, Kymry, Johansen, Berit

“…Rheumatoid arthritis (RA) is an inflammatory disease of the joint characterized by chronic synovitis causing pain, swelling and loss of function due to…”
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Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes by Sommerfelt, Randi M, Feuerherm, Astrid J, Skuland, Trine, Johansen, Berit

“…Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovitis leading to destruction of cartilage and bone. PLA2 enzymes are key…”
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cPLA2α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation by Ashcroft, Felicity J., Mahammad, Nur, Midtun Flatekvål, Helene, J. Feuerherm, Astrid, Johansen, Berit

“…As a regulator of cellular inflammation and proliferation, cytosolic phospholipase A2 α (cPLA2α) is a promising therapeutic target for psoriasis; indeed, the…”
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The Copenhagen Actinic Keratosis Study (COAKS). A decentralised clinical trial to evaluate tolerability, safety and efficacy of daily field-directed topical treatment with cytosolic phospholipase A2 inhibitor, AVX001, in participants with actinic keratosis: protocol for a randomised controlled phase I/IIa trial by Ortner, Vinzent Kevin, Johansen, Berit, Kilov, Kim, Castillo Mondragón, Alejandro, Duvold, Tore, Kihl, Jesper, Ashcroft, Felicity J, Feuerherm, Astrid J, Pind Laugesen, Charlotte, Marcker Espersen, Maiken Lise, Manole, Ionela, Isberg, Ari Pall, Andersen, Anders Daniel, Rakvaag, Elin, Zibert, John R, Haedersdal, Merete

“…IntroductionActinic keratosis (AK) is the most common precancerous skin condition caused by long-term UV exposure. Given the high recurrence rate of 15%–53%,…”
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The ω3‐polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A2 and suppress PGE2 formation in mesangial cells by Huwiler, Andrea, Feuerherm, Astrid J, Sakem, Benjamin, Pastukhov, Oleksandr, Filipenko, Iuliia, Nguyen, Thuy, Johansen, Berit

“…Background and Purpose ω3‐polyunsaturated fatty acids (ω3‐PUFAs) are known to exert anti‐inflammatory effects in various disease models although their direct…”
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LysoPC and PAF Trigger Arachidonic Acid Release by Divergent Signaling Mechanisms in Monocytes by Oestvang, Janne, Anthonsen, Marit W., Johansen, Berit

“…Oxidized low-density lipoproteins (LDLs) play an important role during the development of atherosclerosis characterized by intimal inflammation and macrophage…”
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Anti-inflammatory and antioxidant activities of Sclerochloa dura (Poaceae) by Bukhari Syed Majid, Feuerherm Astrid Jullumstrø, Boulfrad Fayssal, Zlatkovic Bojan, Johansen Berit, Simic Nebojsa

“…The plant Sclerochloa dura is traditionally used in South-East Serbia to treat menstrual disorders characterized by pain and excessive bleeding. According to…”
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Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition by Ghesquiere, Stijn A.I., Gijbels, Marion J.J., Anthonsen, Marit, van Gorp, Patrick J.J., van der Made, Ingeborg, Johansen, Berit, Hofker, Marten H., de Winther, Menno P.J.

“…Atherosclerosis is a chronic inflammatory disease of the vessel wall characterized by the accumulation of lipid-laden macrophages and fibrotic material. The…”
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A novel compound isolated from Sclerochloa dura has anti-inflammatory effects by Bukhari Syed Majid, Feuerherm Astrid Jullumstrø, Tunset Hanna Maja, Isaksen Stian Moe, Sæther Mari, Thvedt Thor Håkon Krane, Gonzalez Susana Villa, Schmid Rudolf, Brunsvik Anders, Fuglseth Erik, Zlatković Bojan, Johansen Berit, Simić Nebojša

“…The activation of PLA2 by means of pro-inflammatory cytokines results in the subsequent release of arachidonic acid (AA) and generates eicosanoids, which…”
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Balanced caloric macronutrient composition downregulates immunological gene expression in human blood cells-adipose tissue diverges by Brattbakk, Hans-Richard, Arbo, Ingerid, Aagaard, Siv, Lindseth, Inge, de Soysa, Ann Kristin Hjelle, Langaas, Mette, Kulseng, Bård, Lindberg, Fedon, Johansen, Berit

“…Cardiovascular disease, obesity, and type 2 diabetes are conditions characterized by low-grade systemic inflammation, strongly influenced by lifestyle, but the…”
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Added clinical value of the inferior temporal EEG electrode chain by Bach Justesen, Anders, Eskelund Johansen, Ann Berit, Martinussen, Noomi Ida, Wasserman, Danielle, Terney, Daniella, Meritam, Pirgit, Gardella, Elena, Beniczky, Sándor

“…•The 10–20 EEG electrode array does not cover the basal part of the temporal lobes.•We extended the 10–20 array with six electrodes in the inferior temporal…”
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Modification of LDL with human secretory phospholipase A2 or sphingomyelinase promotes its arachidonic acid-releasing propensity by Oestvang, Janne, Bonnefont-Rousselot, Dominique, Ninio, Ewa, Hakala, Jukka K., Johansen, Berit, Anthonsen, Marit W.

“…Oxidation and lipolytic remodeling of LDL are believed to stimulate LDL entrapment in the arterial wall, expanding the inflammatory response and promoting…”
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Binding of Human Phospholipase A2 Type II to Proteoglycans by Sartipy, Peter, Johansen, Berit, Camejo, Germán, Rosengren, Birgitta, Bondjers, Göran, Hurt-Camejo, Eva

“…Phospholipase A 2 acting on low density lipoproteins in the extracellular arterial intima may form proinflammatory lipid mediators. Human nonpancreatic…”
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The emerging patent landscape of CRISPR–Cas gene editing technology by Egelie, Knut J, Graff, Gregory D, Strand, Sabina P, Johansen, Berit

“…Early views on the control of the CRISPR–Cas disruptive enabling technology and access for follow-on commercial applications…”
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PhospholipaseA2: A key regulator of inflammatory signalling and a connector to fibrosis development in atherosclerosis by Oestvang, Janne, Johansen, Berit

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Dissociation of Apoptosis Induction and CD36 Upregulation by Enzymatically Modified Low-Density Lipoprotein in Monocytic Cells by Jostarndt, Kristina, Gellert, Nina, Rubic, Tina, Weber, Christian, Kühn, Hartmut, Johansen, Berit, Hrboticky, Nina, Neuzil, Jiri

“…Modified low-density lipoprotein (LDL) has been implicated as an initiating or amplifying factor in atherogenesis. Some of its biological activities, such as…”
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