Search Results - "Johannessen, Cecilie"
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Pharmacology and drug interactions of cannabinoids
Published in Epileptic disorders (01-01-2020)“…ABSTRACT Cannabinoids include a variety of substances, of which cannabidiol (CBD) is the main substance investigated for the treatment of epilepsy, and this…”
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Pharmacological aspects of antiseizure medications: From basic mechanisms to clinical considerations of drug interactions and use of therapeutic drug monitoring
Published in Epileptic disorders (01-08-2023)“…Antiseizure medications (ASMs) are the cornerstone of treatment for patients with epilepsy. Several new ASMs have recently been introduced to the market,…”
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Antiepileptic Drugs in Non-Epilepsy Disorders: Relations between Mechanisms of Action and Clinical Efficacy
Published in CNS drugs (2008)“…Antiepileptic drugs (AEDs) are used extensively to treat multiple non-epilepsy disorders, both in neurology and psychiatry. This article provides a review of…”
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The role of new medical treatments for the management of developmental and epileptic encephalopathies: Novel concepts and results
Published in Epilepsia (Copenhagen) (01-04-2021)“…Developmental and epileptic encephalopathies (DEEs) are among the most challenging of all epilepsies to manage, given the exceedingly frequent and often severe…”
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Drug interactions involving the new second- and third-generation antiepileptic drugs
Published in Expert review of neurotherapeutics (01-01-2010)“…During the period 1989-2009, 14 new antiepileptic drugs (AEDs) were licensed for clinical use and these can be subdivided into new second- and third-generation…”
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Antiepileptic Drug Interactions - Principles and Clinical Implications
Published in Current neuropharmacology (01-09-2010)“…Antiepileptic drugs (AEDs) are widely used as long-term adjunctive therapy or as monotherapy in epilepsy and other indications and consist of a group of drugs…”
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Nonadherence to treatment regimens in epilepsy from the patient's perspective and predisposing factors: Differences between intentional and unintentional lack of adherence
Published in Epilepsia (Copenhagen) (01-05-2019)“…Summary Nonadherence to recommended antiepileptic drug (AED) treatment regimens can result in seizure relapse with increased health risks. Nonadherence can be…”
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Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines
Published in Drug design, development and therapy (01-01-2018)“…Laboratories sometimes use different reference ranges for the same antiepileptic drug (AED), particularly for new and poorly investigated drugs. This may…”
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Therapeutic Drug Monitoring of Lacosamide in Norway: Focus on Pharmacokinetic Variability, Efficacy and Tolerability
Published in Neurochemical research (01-07-2017)“…Lacosamide (LCM) is a new antiepileptic drug (AED). Experience from therapeutic drug monitoring (TDM) in clinical practice is limited. The purpose of this…”
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Pharmacokinetic Variability of Rufinamide and Stiripentol in Children With Refractory Epilepsy: A Retrospective Study of Therapeutic Drug Monitoring From the National Epilepsy Centers in Denmark and Norway
Published in Therapeutic drug monitoring (01-10-2024)“…Rufinamide and stiripentol, orphan drugs used in Lennox-Gastaut and Dravet syndromes, respectively, are antiseizure medications (ASMs), often administered to…”
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Sexual function in people with epilepsy: Similarities and differences with the general population
Published in Epilepsia (Copenhagen) (01-09-2019)“…Objective The potential impact of epilepsy on sexual function is important for patient welfare, but often neglected. This study explored the occurrences of…”
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Pharmacokinetic Variability of Sulthiame: The Impact of Age, Drug-Drug Interactions, and Biochemical Markers of Toxicity in Patients with Epilepsy
Published in Therapeutic drug monitoring (01-04-2024)“…Sulthiame is an antiseizure medication increasingly used for epilepsy. The aim of this study was to investigate the pharmacokinetic variability of sulthiame in…”
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Antiepileptic drug withdrawal in juvenile myoclonic epilepsy
Published in Acta neurologica Scandinavica (01-02-2019)“…Objectives Withdrawal of antiepileptic drugs (AEDs) has been discouraged in juvenile myoclonic epilepsy (JME). However, impulsivity as a consequence of…”
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Relationship between saliva and plasma rufinamide concentrations in patients with epilepsy
Published in Epilepsia (Copenhagen) (01-07-2020)“…The assay of saliva samples provides a valuable alternative to the use of blood samples for therapeutic drug monitoring (TDM), at least for certain categories…”
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Epilepsy and cannabidiol: a guide to treatment
Published in Epileptic disorders (01-02-2020)“…ABSTRACT The growing interest in cannabidiol (CBD), specifically a pure form of CBD, as a treatment for epilepsy, among other conditions, is reflected in…”
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Access to a tailored mobile application enhances medication adherence among young users of antidepressants
Published in Frontiers in pharmacology (10-04-2024)“…Patients' adherence to antidepressants is generally reported to be poor. This study examined whether users of selective serotonin reuptake inhibitors (SSRIs)…”
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Interdisciplinary medication review to improve pharmacotherapy for patients with intellectual disabilities
Published in International journal of clinical pharmacy (01-12-2019)“…Background Patients with intellectual disabilities is an underserved patient group that have poor abilities to express their health complaints. Objective The…”
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Effectiveness and safety of everolimus treatment in patients with tuberous sclerosis complex in real-world clinical practice
Published in Orphanet journal of rare diseases (02-12-2023)“…The randomised double-blinded placebo-controlled EXIST-1-3 studies have showed everolimus effective with adverse effects reported as acceptable in treatment of…”
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Development and validation of a new non-disease-specific survey tool to assess self-reported adherence to medication
Published in Frontiers in pharmacology (07-12-2022)“…Patients' non-adherence to medication affects both patients themselves and healthcare systems. Consequences include higher mortality, worsening of disease,…”
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Therapeutic drug monitoring of gabapentin in various indications
Published in Acta neurologica Scandinavica (01-05-2019)“…Objectives Gabapentin has been increasingly used in various indications in recent years. Despite variable pharmacokinetics, therapeutic drug monitoring (TDM)…”
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