Search Results - "Joh, Richard I."
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1
Nuclear Noncoding RNAs and Genome Stability
Published in Molecular cell (07-07-2016)“…In modern molecular biology, RNA has emerged as a versatile macromolecule capable of mediating an astonishing number of biological functions beyond its role as…”
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2
Small-scale copy number variation and large-scale changes in gene expression
Published in Proceedings of the National Academy of Sciences - PNAS (28-10-2008)“…The expression dynamics of interacting genes depends, in part, on the structure of regulatory networks. Genetic regulatory networks include an…”
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PRIMED: PRIMEr database for deleting and tagging all fission and budding yeast genes developed using the open-source genome retrieval script (GRS)
Published in PloS one (02-02-2015)“…The fission (Schizosaccharomyces pombe) and budding (Saccharomyces cerevisiae) yeasts have served as excellent models for many seminal discoveries in…”
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4
To lyse or not to lyse: transient-mediated stochastic fate determination in cells infected by bacteriophages
Published in PLoS computational biology (01-03-2011)“…Cell fate determination is usually described as the result of the stochastic dynamics of gene regulatory networks (GRNs) reaching one of multiple steady-states…”
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5
Regulation of histone methylation by noncoding RNAs
Published in Biochimica et biophysica acta (01-12-2014)“…Cells can adapt to their environment and develop distinct identities by rewiring their transcriptional networks to regulate the output of key biological…”
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6
RNA quality control factors nucleate Clr4/SUV39H and trigger constitutive heterochromatin assembly
Published in Cell (20-06-2024)“…In eukaryotes, the Suv39 family of proteins tri-methylate lysine 9 of histone H3 (H3K9me) to form constitutive heterochromatin. However, how Suv39 proteins are…”
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7
Dynamics of Indirectly Transmitted Infectious Diseases with Immunological Threshold
Published in Bulletin of mathematical biology (01-05-2009)“…There are numerous examples of human pathogens which persist in environmental reservoirs while infectious outbreaks remain rare. In this manuscript, we…”
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Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs
Published in Molecular cell (15-12-2016)“…Quiescence (G0) is a ubiquitous stress response through which cells enter reversible dormancy, acquiring distinct properties including reduced metabolism,…”
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9
Collective Decision Making in Bacterial Viruses
Published in Biophysical journal (15-09-2008)“…For many bacterial viruses, the choice of whether to kill host cells or enter a latent state depends on the multiplicity of coinfection. Here, we present a…”
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10
Dynamics of Shigellosis Epidemics: Estimating Individual-Level Transmission and Reporting Rates From National Epidemiologic Data Sets
Published in American journal of epidemiology (15-10-2013)“…Shigellosis, a diarrheal disease, is endemic worldwide and is responsible for approximately 15,000 laboratory-confirmed cases in the United States every year…”
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11
To Lyse or Not to Lyse: Transient-Mediated Stochastic Fate Determination in Cells Infected by Bacteriophages: e1002006
Published in PLoS computational biology (01-03-2011)“…Cell fate determination is usually described as the result of the stochastic dynamics of gene regulatory networks (GRNs) reaching one of multiple steady-states…”
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12
PRIMED: PRIMEr Database for Deleting and Tagging All Fission and Budding Yeast Genes Developed Using the Open-Source Genome Retrieval Script (GRS): e0116657
Published in PloS one (01-02-2015)“…The fission (Schizosaccharomyces pombe) and budding (Saccharomyces cerevisiae) yeasts have served as excellent models for many seminal discoveries in…”
Get full text
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