Search Results - "Jofra, T."

Key role of macrophages in tolerance induction via T regulatory type 1 (Tr1) cells by Mfarrej, B., Jofra, T., Morsiani, C., Gagliani, N., Fousteri, G., Battaglia, M.

“…Summary T regulatory type 1 (Tr1) cells are a class of regulatory T cells (Tregs) participating in peripheral tolerance, hence the rationale behind their…”
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Experimental colitis in IL‐10‐deficient mice ameliorates in the absence of PTPN22 by Jofra, T., Galvani, G., Cosorich, I., Giorgi, L., Annoni, A., Vecchione, A., Sorini, C., Falcone, M., Fousteri, G.

“…Summary Interleukin (IL)‐10 plays a key role in controlling intestinal inflammation. IL‐10‐deficient mice and patients with mutations in IL‐10 or its receptor,…”
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The protein tyrosine phosphatase PTPN22 controls forkhead box protein 3 T regulatory cell induction but is dispensable for T helper type 1 cell polarization by Fousteri, G., Jofra, T., Debernardis, I., Stanford, S. M., Laurenzi, A., Bottini, N., Battaglia, M.

“…Summary Protein tyrosine phosphatases (PTPs) regulate T cell receptor (TCR) signalling and thus have a role in T cell differentiation. Here we tested whether…”
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Transplant Tolerance to Pancreatic Islets Is Initiated in the Graft and Sustained in the Spleen by Gagliani, N., Jofra, T., Valle, A., Stabilini, A., Morsiani, C., Gregori, S., Deng, S., Rothstein, D. M., Atkinson, M., Kamanaka, M., Flavell, R. A., Roncarolo, M. G., Battaglia, M.

“…The immune system is comprised of several CD4+ T regulatory (Treg) cell types, of which two, the Foxp3+ Treg and T regulatory type 1 (Tr1) cells, have…”
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Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells by TRESOLDI, Eleonora, DELL'ALBANI, Ilaria, STABILINI, Angela, JOFRA, Tatiana, VALLE, Andrea, GAGLIANI, Nicola, BONDANZA, Attilio, GRAZIA RONCAROLO, Maria, BATTAGLIA, Manuela

“…The clinical use of ex vivo-expanded T-regulatory cells for the treatment of T-cell-mediated diseases has gained increasing momentum. However, the recent…”
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Regulatory T cells from patients with end-stage organ disease can be isolated, expanded and cryopreserved according good manufacturing practice improving their function by Ulbar, Francesca, Montemurro, Tiziana, Jofra, Tatiana, Capri, Miriam, Comai, Giorgia, Bertuzzo, Valentina, Lavazza, Cristiana, Mandelli, Alessandra, Viganò, Mariele, Budelli, Silvia, Bacalini, Maria Giulia, Pirazzini, Chiara, Garagnani, Paolo, Giudice, Valeria, Sollazzo, Daria, Curti, Antonio, Arpinati, Mario, La Manna, Gaetano, Cescon, Matteo, Pinna, Antonio Daniele, Franceschi, Claudio, Battaglia, Manuela, Giordano, Rosaria, Catani, Lucia, Lemoli, Roberto Massimo

“…Here, we isolated, expanded and functionally characterized regulatory T cells (Tregs) from patients with end stage kidney and liver disease, waiting for…”
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Reply to Comment on "Stability of human rapamycin-expanded CD4+CD25+ T-regulatory cells" Haematologica 2011;96(9):1357-65 by Tresoldi, E., Dell'Albani, I., Stabilini, A., Jofra, T., Valle, A., Gagliani, N., Bondanza, A., Roncarolo, M. G., Battaglia, M.

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A New Combined Therapy (anti-CD45RB mAb + rapamycin + IL-10) Able to Induce Active Long-term Tolerance in a Stringent Pre-clinical Model of Allogeneic Islet Transplantation by Gagliani, Nicola, Jofra, Tatiana, Gregori, Silvia, Battaglia, Manuela, Roncarolo, Maria Grazia

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