Search Results - "Joffe, Hadine"

Sex and Gender Differences in Health: What the COVID-19 Pandemic Can Teach Us by Spagnolo, Primavera A, Manson, JoAnn E, Joffe, Hadine

“…Sex; biological and physiologic traits characterizing males and females; and gender, a continuum of socioculturally constructed roles and behaviors associated…”
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Vasomotor Symptoms and Menopause: Findings from the Study of Women's Health across the Nation by Thurston, Rebecca C., PhD, Joffe, Hadine, MD, MSc

“…Vasomotor symptoms (VMS), or hot flashes and night sweats, are often considered the cardinal symptoms of menopause. SWAN, one of the largest and most…”
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Predictors of increased risk for early treatment non-adherence to oral anti-estrogen therapies in early-stage breast cancer patients by Yusufov, Miryam, Nathan, Margo, Wiley, Aleta, Russell, Julia, Partridge, Ann, Joffe, Hadine

“…Purpose Non-adherence to the oral anti-estrogen therapies (AET) tamoxifen and aromatase inhibitors in early-stage hormone receptor-positive breast cancer is…”
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Duration of menopausal vasomotor symptoms over the menopause transition by Avis, Nancy E, Crawford, Sybil L, Greendale, Gail, Bromberger, Joyce T, Everson-Rose, Susan A, Gold, Ellen B, Hess, Rachel, Joffe, Hadine, Kravitz, Howard M, Tepper, Ping G, Thurston, Rebecca C

“…The expected duration of menopausal vasomotor symptoms (VMS) is important to women making decisions about possible treatments. To determine total duration of…”
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Effects of NT-814, a dual neurokinin 1 and 3 receptor antagonist, on vasomotor symptoms in postmenopausal women: a placebo-controlled, randomized trial by Trower, Mike, Anderson, Richard A., Ballantyne, Elizabeth, Joffe, Hadine, Kerr, Mary, Pawsey, Steve

“…OBJECTIVES:To evaluate the safety, pharmacokinetics, and preliminary efficacy of NT-814, a dual neurokinin 1,3 antagonist, in postmenopausal women with…”
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Reflections on The Lancet menopause Series – Authors' reply by Hickey, Martha, Hunter, Myra S, Crandall, Carolyn J, Joffe, Hadine, Doust, Jennifer, La Croix, Andrea, Mishra, Gita D, Sivakami, Muthusamy, Brown, Lydia

“…[...]for those at average risk, meaningful fracture prevention would require long-term MHT use, which has associated risks.7 Newer products have been approved…”
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Efficacy and safety of elinzanetant, a selective neurokinin-1,3 receptor antagonist for vasomotor symptoms: a dose-finding clinical trial (SWITCH-1) by Simon, James A., Anderson, Richard A., Ballantyne, Elizabeth, Bolognese, James, Caetano, Cecilia, Joffe, Hadine, Kerr, Mary, Panay, Nick, Seitz, Christian, Seymore, Susan, Trower, Mike, Zuurman, Lineke, Pawsey, Steve

“…Neurokinin (NK)-3 and NK-1 receptors have been implicated in the etiology of vasomotor symptoms (VMS) and sleep disturbances associated with menopause. This…”
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Menopausal hormone therapy trends before versus after 2002: impact of the Womenʼs Health Initiative Study Results by Crawford, Sybil L, Crandall, Carolyn J, Derby, Carol A, Khoudary, Samar R El, Waetjen, L Elaine, Fischer, Mary, Joffe, Hadine

“…OBJECTIVE:To better understand how to educate patients and providers about study findings relevant to treatment guidelines, we assessed pre- versus…”
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Ovarian Hormone Fluctuation, Neurosteroids, and HPA Axis Dysregulation in Perimenopausal Depression: A Novel Heuristic Model by Gordon, Jennifer L., Girdler, Susan S., Meltzer-Brody, Samantha E., Stika, Catherine S., Thurston, Rebecca C., Clark, Crystal T., Prairie, Beth A., Moses-Kolko, Eydie, Joffe, Hadine, Wisner, Katherine L.

“…Objective:In this conceptual review, the authors propose a novel mechanistic candidate in the etiology of depression with onset in the menopause transition…”
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Sex-Based Dimorphism of Anticancer Immune Response and Molecular Mechanisms of Immune Evasion by Conforti, Fabio, Pala, Laura, Pagan, Eleonora, Bagnardi, Vincenzo, De Pas, Tommaso, Queirolo, Paola, Pennacchioli, Elisabetta, Catania, Chiara, Cocorocchio, Emilia, Ferrucci, Pier Francesco, Saponara, Maristella, Orsolini, Gianmarco, Zagami, Paola, Nicoló, Eleonora, De Marinis, Filippo, Tortora, Giampaolo, Bria, Emilio, Minucci, Saverio, Joffe, Hadine, Veronesi, Paolo, Wargo, Jennifer, Rosenthal, Rachel, Swanton, Charles, Mantovani, Alberto, Gelber, Richard D, Viale, Giuseppe, Goldhirsch, Aron, Giaccone, Giuseppe

“…We previously demonstrated that sex influences response to immune checkpoint inhibitors. In this article, we investigate sex-based differences in the molecular…”
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Menopausal Vasomotor Symptoms and Risk of Incident Cardiovascular Disease Events in SWAN by Thurston, Rebecca C, Aslanidou Vlachos, Helen E, Derby, Carol A, Jackson, Elizabeth A, Brooks, Maria Mori, Matthews, Karen A, Harlow, Sioban, Joffe, Hadine, El Khoudary, Samar R

“…Background Cardiovascular disease (CVD) in women has unique features, including associations with reproductive factors that are incompletely understood…”
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Antimullerian Hormone and Impending Menopause in Late Reproductive Age: The Study of Women’s Health Across the Nation by Finkelstein, Joel S, Lee, Hang, Karlamangla, Arun, Neer, Robert M, Sluss, Patrick M, Burnett-Bowie, Sherri-Ann M, Darakananda, Karin, Donahoe, Patricia K, Harlow, Sioban D, Prizand, Sarah H, Joffe, Hadine, Kumar, Ajay, Martin, Deborah E, McConnell, Daniel, Merrilat, Steffenie, Morrison, Anthony, Pastore, Lisa M, Randolph, John F, Greendale, Gail A, Santoro, Nanette

“…Abstract Background A test that helps predict the time to the final menstrual period (FMP) has been sought for many years. Objective To assess the ability of…”
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Sleep During the Perimenopause: A SWAN Story by Kravitz, Howard M., DO, MPH, Joffe, Hadine, MD, MSc

“…Is there evidence for a perimenopausal sleep disorder? We address this question in our presentation of the Study of Women's Health Across the Nation (SWAN)…”
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Vasomotor symptoms in midlife women with incident breast cancer: pink SWAN by Gold, Ellen B., Crawford, Sybil L., Leung, Katherine, Greendale, Gail, Reeves, Katherine W., Joffe, Hadine, Avis, Nancy E.

“…Purpose We compared trajectories of vasomotor symptoms (VMS) and their risk factors in women with breast cancer (BrCa) to those of cancer-free controls…”
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Vasomotor Symptoms and Insulin Resistance in the Study of Women's Health Across the Nation by Thurston, Rebecca C, El Khoudary, Samar R, Sutton-Tyrrell, Kim, Crandall, Carolyn J, Sternfeld, Barbara, Joffe, Hadine, Gold, Ellen B, Selzer, Faith, Matthews, Karen A

“…Context: Emerging research suggests links between menopausal hot flashes and cardiovascular disease risk. The mechanisms underlying these associations are…”
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Trajectory Clustering of Estradiol and Follicle-Stimulating Hormone during the Menopausal Transition among Women in the Study of Women's Health across the Nation (SWAN) by Tepper, Ping G, Randolph, John F, McConnell, Daniel S, Crawford, Sybil L, El Khoudary, Samar R, Joffe, Hadine, Gold, Ellen B, Zheng, Huiyong, Bromberger, Joyce T, Sutton-Tyrrell, Kim

“…Context: Variability in the pattern of change in estradiol (E2) and FSH levels over the menopause transition has not been well defined. Objective: The current…”
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Longitudinal Association Between Depressive Symptoms and Multidimensional Sleep Health: The SWAN Sleep Study by Bowman, Marissa A, Kline, Christopher E, Buysse, Daniel J, Kravitz, Howard M, Joffe, Hadine, Matthews, Karen A, Bromberger, Joyce T, Roecklein, Kathryn A, Krafty, Robert T, Hall, Martica H

“…Abstract Background Depressive symptoms and sleep disturbances disproportionately affect midlife women. While there may be a bidirectional association, few…”
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Plasma androgens and the presence and course of depression in a large cohort of women by de Wit, Anouk E., Giltay, Erik J., de Boer, Marrit K., Bosker, Fokko J., Cohn, Aviva Y., Nolen, Willem A., Kaiser, Ursula B., Joffe, Hadine, Penninx, Brenda W.J.H., Schoevers, Robert A.

“…Major depressive disorder (MDD) has a higher prevalence in women with supraphysiologic androgen levels. Whether there is also an association between depression…”
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The Impact of Depot GnRH Agonist on AMH Levels in Healthy Reproductive-Aged Women by Su, H. Irene, Maas, Kevin, Sluss, Patrick M, Chang, R. Jeffrey, Hall, Janet E, Joffe, Hadine

“…Context: GnRH agonists (GnRHa) are being used experimentally in an attempt to preserve fertility in young female cancer patients undergoing chemotherapy…”
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Menopausal quality of life: RCT of yoga, exercise, and omega-3 supplements by Reed, Susan D., MD, Guthrie, Katherine A., PhD, Newton, Katherine M., PhD, Anderson, Garnet L., PhD, Booth-LaForce, Cathryn, PhD, Caan, Bette, DrPH, Carpenter, Janet S., PhD, Cohen, Lee S., MD, Dunn, Andrea L., PhD, Ensrud, Kristine E., MD, Freeman, Ellen W., PhD, Hunt, Julie R., PhD, Joffe, Hadine, MD, Larson, Joseph C., MS, Learman, Lee A., MD, Rothenberg, Robin, BS, Seguin, Rebecca A., PhD, Sherman, Karen J., PhD, Sternfeld, Barbara S., PhD, LaCroix, Andrea Z., PhD

“…Objective The purpose of this study was to determine the efficacy of 3 nonhormonal therapies for the improvement of menopause-related quality of life in women…”
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