Search Results - "Joergensen, Flemming S"
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GABAA Receptor Agonists, Partial Agonists, and Antagonists. Design and Therapeutic Prospects
Published in Journal of medicinal chemistry (01-08-1994)Get full text
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Conservation of a helix-stabilizing dipole moment in the PP-fold family of regulatory peptides
Published in Biochemistry (Easton) (01-03-1993)“…Investigation of the charge distribution for all known members of the PP-fold family of peptides reveals a common pattern characterized by a cluster of…”
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Relationship between structure, conformational flexibility, and biological activity of agonists and antagonists at the N-methyl-D-aspartic acid subtype of excitatory amino acid receptors
Published in Journal of medicinal chemistry (01-01-1990)“…The relationship between conformational flexibility and agonist or antagonist actions at the N-Methyl-D-aspartic acid (NMDA) subtype of central L-glutamic acid…”
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New leads of metallo-β-lactamase inhibitors from structure-based pharmacophore design
Published in Bioorganic & medicinal chemistry (15-04-2006)“…We have applied pharmacophore generation, database searching, docking methodologies, and experimental enzyme kinetics to discover new structures for design of…”
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Crystal and molecular structure of anti-sesquinorbornene
Published in Journal of organic chemistry (01-11-1985)Get full text
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Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum
Published in Malaria journal (12-06-2004)“…The aim of this study was to develop site-specific antibodies as a tool to capture Plasmodium falciparum-dihydrofolate reductase (Pf-DHFR) from blood samples…”
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