Search Results - "Joensuu, Kristiina"
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Quantities of CD3+, CD8+ and CD56+ lymphocytes decline in breast cancer recurrences while CD4+ remain similar
Published in Diagnostic pathology (10-01-2023)“…Much is known about tumor infiltrating lymphocytes (Tils) in primary breast cancer, as this has been the focus of much research in recent years, but regarding…”
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Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch
Published in Proceedings of the National Academy of Sciences - PNAS (21-02-2012)“…Luminal breast cancers express estrogen (ER) and/or progesterone (PR) receptors and respond to hormone therapies. Basal-like "triple negative" cancers lack…”
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Tumor dormancy: Elevated expression of stanniocalcins in late relapsing breast cancer
Published in Cancer letters (28-06-2008)“…Abstract Background Breast cancer is known for its propensity to recur even after decades. The biology behind this phenomenon of tumor dormancy is poorly…”
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ER,PR, HER2, Ki-67 and CK5 in Early and Late Relapsing Breast Cancer- Reduced CK5 Expression in Metastases
Published in Breast Cancer: Basic and Clinical Research (01-01-2013)“…Breast cancer can recur even decades after the primary therapy. Markers are needed to predict cancer progression and the risk of late recurrence. The estrogen…”
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High expression of maspin is associated with early tumor relapse in breast cancer
Published in Human pathology (01-08-2009)“…Summary Maspin is a serine protease inhibitor with tumor suppressor activity. Maspin can suppress tumor growth and metastasis in vivo and tumor cell motility…”
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High expression of CCL2 in tumor cells and abundant infiltration with CD14 positive macrophages predict early relapse in breast cancer
Published in Virchows Archiv : an international journal of pathology (01-01-2019)“…Macrophages are important for the function of the innate immune system, and in solid tumors, they represent a significant proportion of the tumor mass…”
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Core needle biopsy changes the expression of TGFβ1 and TGFβRII at protein level, and the distribution of CD4 and CD8 positive T cells in primary breast cancer
Published in Pathology, research and practice (01-08-2024)“…Core needle biopsy (CNB) has become a paradigm in preoperative breast cancer (BC) diagnosis. Although considered safe, it is an invasive procedure, which…”
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Clever-1 positive macrophages in breast cancer
Published in Breast cancer research and treatment (01-10-2022)“…Purpose Common Lymphatic Endothelial and Vascular Endothelial Receptor 1 (Clever-1) is expressed by a subset of immunosuppressive macrophages and targeting the…”
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Core needle biopsies alter the amounts of CCR5, Siglec-15, and PD-L1 positivities in breast carcinoma
Published in Virchows Archiv : an international journal of pathology (01-08-2023)“…Core needle biopsies (CNB) are widely used to diagnose breast cancer, but the procedure is invasive and thus, it changes the tumor microenvironment. The…”
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Core Needle Biopsy Enhances the Activity of the CCL2/CCR2 Pathway in the Microenvironment of Invasive Breast Cancer
Published in Onco (30-12-2021)“…The use of core needle biopsy (CNB) as a means to verify malignancy preoperatively is a paradigm in current breast cancer care, and the risk of enhancing tumor…”
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Social Proximity and Environmental NGO Relationships in Corporate Sustainability Reports
Published in Sustainable development (Bradford, West Yorkshire, England) (01-01-2015)“…This study demonstrates how three Finnish companies constructed their stakeholder relationships with environmental NGOs (ENGOs) in terms of social proximity in…”
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Different Expression Patterns of CXCR4, CCR7, Maspin and FOXP3 in Luminal Breast Cancers and Their Sentinel Node Metastases
Published in Anticancer research (01-01-2017)“…Luminal A breast cancers (BC) represent low-risk tumors conferring better outcome than luminal B and human epidermal growth factor 2 (HER2)-positive or…”
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Luminal breast cancer metastases and tumor arousal from dormancy are promoted by direct actions of estradiol and progesterone on the malignant cells
Published in Breast cancer research : BCR (05-12-2014)“…Luminal, estrogen receptor-positive (ER(+)) breast cancers can metastasize but lie dormant for years before recurrences prove lethal. Understanding the roles…”
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Implications of Managerial Framing of Stakeholders in Environmental Reports
Published in Social and environmental accountability journal (02-09-2014)“…Corporate environmental reports are increasingly viewed as products of the managerial framing of responsibility and stakeholders. This notion encouraged us to…”
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Bmi-1, c-myc, and Snail expression in primary breast cancers and their metastases—elevated Bmi-1 expression in late breast cancer relapses
Published in Virchows Archiv : an international journal of pathology (01-07-2011)“…Breast cancer is known for its propensity to recur decades after treatment. The biology behind the phenomenon of tumor dormancy is still poorly understood…”
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ER, PR, HER2, Ki-67 and CK5 in Early and Late Relapsing Breast Cancer—Reduced CK5 Expression in Metastases
Published in Breast cancer : basic and clinical research (01-01-2013)“…Breast cancer can recur even decades after the primary therapy. Markers are needed to predict cancer progression and the risk of late recurrence. The estrogen…”
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Fatal epithelioid haemangioendothelioma presenting in the lung and liver
Published in Virchows Archiv A Pathological Anatomy and Histopathology (1986)Get full text
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Dormancy of tumor cells
Published in Duodecim (Helsinki, Finland : 1961) (2013)“…Whereas tumor dormancy occurs in melanomas, renal carcinomas and non-Hodgkin lymphomas, late recurrence is characteristic of breast cancer in particular. In…”
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