Search Results - "Joel, Bumgardner"

An overview of chitin or chitosan/nano ceramic composite scaffolds for bone tissue engineering by Deepthi, S., Venkatesan, J., Kim, Se-Kwon, Bumgardner, Joel D., Jayakumar, R.

“…Chitin and chitosan based nanocomposite scaffolds have been widely used for bone tissue engineering. These chitin and chitosan based scaffolds were reinforced…”
Get full text

A Study of Combining Elastin in the Chitosan Electrospinning to Increase the Mechanical Strength and Bioactivity by Su, Hengjie, Fujiwara, Tomoko, Bumgardner, Joel D

“…While electrospun chitosan membranes modified to retain nanofibrous morphology have shown promise for use in guided bone regeneration applications in in vitro…”
Get full text

A chitosan/β-glycerophosphate thermo-sensitive gel for the delivery of ellagic acid for the treatment of brain cancer by Kim, Sungwoo, Nishimoto, Satoru K, Bumgardner, Joel D, Haggard, Warren O, Gaber, M. Waleed, Yang, Yunzhi

“…Abstract We report here the development of a chitosan/β-glycerophosphate(Ch/β-GP) thermo-sensitive gel to deliver ellagic acid (EA) for cancer treatment. The…”
Get full text

Deacetylation of Chitosan: Material Characterization and in vitro Evaluation via Albumin Adsorption and Pre-Osteoblastic Cell Cultures by Yuan, Youling, Chesnutt, Betsy M, Haggard, Warren O, Bumgardner, Joel D

“…Degree of deacetylation (DDA) and molecular weight (MW) of chitosans are important to their physical and biological properties. In this study, two chitosans,…”
Get full text

Modified electrospun chitosan membranes for controlled release of simvastatin by Murali, Vishnu Priya, Fujiwara, Tomoko, Gallop, Caleb, Wang, Yongmei, Wilson, Jack A., Atwill, Matthew Thomas, Kurakula, Mallesh, Bumgardner, Joel D.

“…[Display omitted] Chitosan nanofibrous membranes have immense potential in tissue engineering and drug delivery applications because of their increased surface…”
Get full text

A comparison of two types of electrospun chitosan membranes and a collagen membrane in vivo by Su, Hengjie, Fujiwara, Tomoko, Anderson, Kenneth M., Karydis, Anastasios, Ghadri, M. Najib, Bumgardner, Joel D.

“…Electrospun chitosan membranes subjected to post-spinning processes using either triethylamine/tert-butyloxycarbonyl (TEA/tBOC) or butyryl-anhydride (BA)…”
Get full text

Porous Nano-Fiber Structure of Modified Electrospun Chitosan GBR Membranes Improve Osteoblast Calcium Phosphate Deposition in Osteoblast-Fibroblast Co-Cultures by Su, Hengjie, Fujiwara, Tomoko, Skalli, Omar, Selders, Gretchen Schreyack, Li, Ting, Mao, Linna, Bumgardner, Joel D

“…Desirable characteristics of electrospun chitosan membranes (ESCM) for guided bone regeneration are their nanofiber structure that mimics the extracellular…”
Get full text

Antibacterial and biocompatible polyaniline‐doped titanium oxide layers by Ali, Aya, Chowdhury, Sheetal, Carr, Mary A., Janorkar, Amol V., Marquart, Mary, Griggs, Jason A., Bumgardner, Joel D., Roach, Michael D.

“…Titanium anodization has been shown to produce crystalline oxides exhibiting photocatalytic reactions that form reactive oxygen species (ROS) when exposed to…”
Get full text

Long‐Term Controlled Release of Simvastatin from Photoprinted Triple‐Networked Hydrogels Composed of Modified Chitosan and PLA–PEG Micelles by Cisneros, Karla, Chowdhury, Naisha, Coleman, Emily, Ferdous, Tamanna, Su, Hengjie, Jennings, Jessica A., Bumgardner, Joel D., Fujiwara, Tomoko

“…Local delivery of active agents using injectable or implantable hydrogels for tissue and bone regeneration is a promising therapy, but it remains challenging…”
Get full text

Pyridine catalyzed acylation of electrospun chitosan membranes by C6-C12 acyl chlorides: Effect of reaction time and chain length by Yeasmin, Rabeta, Abuhussein, Ezzuddin, Perez, Felio, Fujiwara, Tomoko, Bumgardner, Joel D, Jennings, Jessica Amber

“…Chitosan nanofiber membranes manufactured via electrospinning are attractive for drug delivery applications due to their increased surface area. The as-spun…”
Get full text

Magnetic stimuli-responsive chitosan-based drug delivery biocomposite for multiple triggered release by Harris, Michael, Ahmed, Hamza, Barr, Brandico, LeVine, David, Pace, Leslie, Mohapatra, Ankita, Morshed, Bashir, Bumgardner, Joel D., Jennings, Jessica Amber

“…Stimuli-responsive biomaterials offer a unique advantage over traditional local drug delivery systems in that the drug elution rate can be controllably…”
Get full text

In vitro evaluation of loaded chitosan membranes for pain relief and infection prevention by Harrison, Zoe L., Bumgardner, Joel D., Fujiwara, Tomoko, Baker, Daniel L., Jennings, J. Amber

“…Wounds resulting from surgeries, implantation of medical devices, and musculoskeletal trauma result in pain and can also result in infection of damaged tissue…”
Get full text

Evaluation of Magnesium-Phosphate Particle Incorporation into Co-Electrospun Chitosan-Elastin Membranes for Skin Wound Healing by Bryan, Alex, Wales, Ethan, Vedante, Samarth, Blanquer, Andreu, Neupane, Dipesh, Mishra, Sanjay, Bačáková, Lucie, Fujiwara, Tomoko, Jennings, Jessica Amber, Bumgardner, Joel D.

“…Major challenges facing clinicians treating burn wounds are the lack of integration of treatment to wound, inadequate mechanical properties of treatments, and…”
Get full text

Nano-fibrin stabilized CaSO4 crystals incorporated injectable chitin composite hydrogel for enhanced angiogenesis & osteogenesis by Arun Kumar, R., Sivashanmugam, A., Deepthi, S., Bumgardner, Joel D., Nair, Shantikumar V., Jayakumar, R.

“…•The prepared chitin–CaSO4–nFibrin injectable gel showed osteoangiogenic properties.•nFibrin addition transformed the CaSO4 crystal shape from needle to…”
Get full text

Titanium coated with 2-decenoic analogs reduces bacterial and fungal biofilms by Harrison, Zoe L, Montgomery, Emily C, Hoffman, Brian, Perez, Felio, Bush, Joshua R, Bumgardner, Joel D, Fujiwara, Tomoko, Baker, Daniel L, Jennings, J Amber

“…Due to antibiotic tolerance of microbes within a biofilm, non-antibiotic methods for prevention and treatment of implant-related infections are preferable. The…”
Get full text

Chitosan Films: A Potential Local Drug Delivery System for Antibiotics by Noel, Scott P., Courtney, Harry, Bumgardner, Joel D., Haggard, Warren O.

“…Local antibiotic delivery is an emerging area of study designed to provide alternative methods of treatment to clinicians for compromised wound sites where…”
Get full text

Tetracycline nanoparticles loaded calcium sulfate composite beads for periodontal management by Sindhura Reddy, N, Sowmya, S, Bumgardner, Joel D, Chennazhi, K P, Biswas, Raja, Jayakumar, R

“…The objective of this study was to fabricate, characterize and evaluate in vitro, an injectable calcium sulfate bone cement beads loaded with an antibiotic…”
Get full text

Composite chitosan/nano-hydroxyapatite scaffolds induce osteocalcin production by osteoblasts in vitro and support bone formation in vivo by Chesnutt, Betsy M, Yuan, Youling, Buddington, Karyl, Haggard, Warren O, Bumgardner, Joel D

“…There is a significant clinical need to develop alternatives to autografts and allografts for bone grafting procedures. Porous, biodegradable scaffolds based…”
Get more information

Chitosan Sponges to Locally Deliver Amikacin and Vancomycin: A Pilot In Vitro Evaluation by Noel, Scott P., Courtney, Harry S., Bumgardner, Joel D., Haggard, Warren O.

“…Background Open orthopaedic wounds are ideal sites for infection. Preventing infection in these wounds is critical for reducing patient morbidity and…”
Get full text

Staphylococcal infection prevention using antibiotic‐loaded mannitol–chitosan paste in a rabbit model of implant‐associated osteomyelitis by Harrison, Zoe L., Pace, Leslie R., Brown, Madison N., Beenken, Karen E., Smeltzer, Mark S., Bumgardner, Joel D., Haggard, Warren O., Amber Jennings, J.

“…Antibiotic‐loaded chitosan pastes have shown advantages in the treatment and coverage of complex musculoskeletal defects. We added mannitol, previously shown…”
Get full text