Search Results - "Joe, A."

Recent progress in consolidated bioprocessing by Olson, Daniel G, McBride, John E, Joe Shaw, A, Lynd, Lee R

“…Highlights ► Substantial progress has been made in the development of CBP. ► Production of ethanol at high yield and titer using ‘native strategy’. ►…”
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Intracellular Polyphenols: How Little We Know by Vinson, Joe A

“…In vitro cell studies are used by scientists to determine mechanisms that can be operating in vivo and pave the way for animal and human studies. Polyphenols,…”
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Ancestral sequence reconstruction for protein engineers by Spence, Matthew A., Kaczmarski, Joe A., Saunders, Jake W., Jackson, Colin J.

“…In addition to its value in the study of molecular evolution, ancestral sequence reconstruction (ASR) has emerged as a useful methodology for engineering…”
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Nuts, especially walnuts, have both antioxidant quantity and efficacy and exhibit significant potential health benefits by Vinson, Joe A, Cai, Yuxing

“…Free and total (after basic hydrolysis) polyphenols in nine types of raw and roasted nuts and two types of peanut butter (54 commercial samples) were analyzed…”
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Novel concepts on the role of prostaglandins on luteal maintenance and maternal recognition and establishment of pregnancy in ruminants by Arosh, Joe A, Banu, Sakhila K, McCracken, John A

“…In ruminants, the corpus luteum (CL) of early pregnancy is resistant to luteolysis. Prostaglandin (PG)E2 is considered a luteoprotective mediator. Early…”
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Endocrine disruptors and endometriosis by Dutta, Sudipta, Banu, Sakhila K., Arosh, Joe A.

“…Endometriosis is a hormone-dependent inflammatory gynecological disease of reproductive-age women. It is clinically and pathologically characterized by the…”
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Experimental Platform for Ultra-high Dose Rate FLASH Irradiation of Small Animals Using a Clinical Linear Accelerator by Schüler, Emil, PhD, Trovati, Stefania, PhD, King, Gregory, PhD, Lartey, Frederick, PhD, Rafat, Marjan, PhD, Villegas, Manuel, Praxel, A. Joe, Loo, Billy W., MD, PhD, Maxim, Peter G., PhD

“…Purpose A key factor limiting the effectiveness of radiation therapy is normal tissue toxicity, and recent preclinical data have shown that ultra-high dose…”
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Directed in Vitro Evolution of Therapeutic Bacteriophages: The Appelmans Protocol by Burrowes, Ben H, Molineux, Ian J, Fralick, Joe A

“…The 'Appelmans protocol' is used by Eastern European researchers to generate therapeutic phages with novel lytic host ranges. Phage cocktails are iteratively…”
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Dual inhibition of AKT and ERK1/2 pathways restores the expression of progesterone Receptor-B in endometriotic lesions through epigenetic mechanisms by Dutta, Sudipta, Lee, JeHoon, Banu, Sakhila K., Arosh, Joe A.

“…Endometriosis is an estrogen-dependent and progesterone-resistant gynecological inflammatory disease of reproductive-age women. Progesterone resistance, loss…”
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Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding protein by Clifton, Ben E., Kaczmarski, Joe A., Carr, Paul D., Gerth, Monica L., Tokuriki, Nobuhiko, Jackson, Colin J.

“…The emergence of enzymes through the neofunctionalization of noncatalytic proteins is ultimately responsible for the extraordinary range of biological…”
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Improved Gene Targeting through Cell Cycle Synchronization by Tsakraklides, Vasiliki, Brevnova, Elena, Stephanopoulos, Gregory, Shaw, A Joe

“…Gene targeting is a challenge in organisms where non-homologous end-joining is the predominant form of recombination. We show that cell division cycle…”
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Effects of dual inhibition of AKT and ERK1/2 pathways on endometrial pro-inflammatory, hormonal, and epigenetic microenvironment in endometriosis by Arosh, Joe A., Lee, JeHoon, Banu, Sakhila K.

“…Endometriosis is an estrogen-dependent and progesterone-resistant gynecological inflammatory disease of reproductive-age women. The prevalence of endometriosis…”
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Metabolic engineering of microbial competitive advantage for industrial fermentation processes by Shaw, A. Joe, Lam, Felix H., Hamilton, Maureen, Consiglio, Andrew, MacEwen, Kyle, Brevnova, Elena E., Greenhagen, Emily, LaTouf, W. Greg, South, Colin R., van Dijken, Hans, Stephanopoulos, Gregory

“…Microbial contamination is an obstacle to widespread production of advanced biofuels and chemicals. Current practices such as process sterilization or…”
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Berry anthocyanins as novel antioxidants in human health and disease prevention by Zafra-Stone, Shirley, Yasmin, Taharat, Bagchi, Manashi, Chatterjee, Archana, Vinson, Joe A., Bagchi, Debasis

“…Edible berries, a potential source of natural anthocyanin antioxidants, have demonstrated a broad spectrum of biomedical functions. These include…”
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Genetic engineering of grass cell wall polysaccharides for biorefining by Bhatia, Rakesh, Gallagher, Joe A., Gomez, Leonardo D., Bosch, Maurice

“…Summary Grasses represent an abundant and widespread source of lignocellulosic biomass, which has yet to fulfil its potential as a feedstock for biorefining…”
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Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme by Kaczmarski, Joe A., Mahawaththa, Mithun C., Feintuch, Akiva, Clifton, Ben E., Adams, Luke A., Goldfarb, Daniella, Otting, Gottfried, Jackson, Colin J.

“…Several enzymes are known to have evolved from non-catalytic proteins such as solute-binding proteins (SBPs). Although attention has been focused on how a…”
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Binding of Plant Polyphenols to Serum Albumin and LDL: Healthy Implications for Heart Disease by Poloni, Dana M, Dangles, Olivier, Vinson, Joe A

“…Cardiovascular disease (CVD) is the leading cause of death in industrialized nations. The initiating event in atherosclerosis, or hardening of the arteries, is…”
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Sensitivity of Tidewater Glaciers to Submarine Melting Governed by Plume Locations by Cowton, Tom R., Todd, Joe A., Benn, Douglas I.

“…The response of tidewater glaciers to ocean warming remains a key uncertainty in sea level rise predictions. Here we use a 3‐D numerical model to examine the…”
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Understanding how cystic fibrosis mutations disrupt CFTR function: From single molecules to animal models by Wang, Yiting, Wrennall, Joe A., Cai, Zhiwei, Li, Hongyu, Sheppard, David N.

“…Defective epithelial ion transport is the hallmark of the life-limiting genetic disease cystic fibrosis (CF). This abnormality is caused by mutations in the…”
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Structural and evolutionary approaches to the design and optimization of fluorescence-based small molecule biosensors by Kaczmarski, Joe A, Mitchell, Joshua A, Spence, Matthew A, Vongsouthi, Vanessa, Jackson, Colin J

“…[Display omitted] •Designing genetically encoded fluorescence-based analyte biosensors is not trivial.•Many current design efforts take a nature-inspired,…”
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