Search Results - "Joan Pous"

Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism by Cuervo, Ana, Fàbrega-Ferrer, Montserrat, Machón, Cristina, Conesa, José Javier, Fernández, Francisco J., Pérez-Luque, Rosa, Pérez-Ruiz, Mar, Pous, Joan, Vega, M. Cristina, Carrascosa, José L., Coll, Miquel

“…Double-stranded DNA bacteriophages package their genome at high pressure inside a procapsid through the portal, an oligomeric ring protein located at a unique…”
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Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α by Pous, Joan, Baginski, Blazej, Martin-Malpartida, Pau, González, Lorena, Scarpa, Margherita, Aragon, Eric, Ruiz, Lidia, Mees, Rebeca A., Iglesias-Fernández, Javier, Orozco, Modesto, Nebreda, Angel R., Macias, Maria J.

“…Many functional aspects of the protein kinase p38α have been illustrated by more than three hundred structures determined in the presence of reducing agents…”
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Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway by González, Lorena, Díaz, Lucía, Pous, Joan, Baginski, Blazej, Duran-Corbera, Anna, Scarpa, Margherita, Brun-Heath, Isabelle, Igea, Ana, Martin-Malpartida, Pau, Ruiz, Lidia, Pallara, Chiara, Esguerra, Mauricio, Colizzi, Francesco, Mayor-Ruiz, Cristina, Biondi, Ricardo M., Soliva, Robert, Macias, Maria J., Orozco, Modesto, Nebreda, Angel R.

“…p38α is a versatile protein kinase that can control numerous processes and plays important roles in the cellular responses to stress. Dysregulation of p38α…”
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The Birnavirus Crystal Structure Reveals Structural Relationships among Icosahedral Viruses by Coulibaly, Fasséli, Chevalier, Christophe, Gutsche, Irina, Pous, Joan, Navaza, Jorge, Bressanelli, Stéphane, Delmas, Bernard, Rey, Félix A.

“…Double-stranded RNA virions are transcriptionally competent icosahedral particles that must translocate across a lipid bilayer to function within the cytoplasm…”
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Crystal structure of a complex of DNA with one AT-hook of HMGA1 by Fonfría-Subirós, Elsa, Acosta-Reyes, Francisco, Saperas, Núria, Pous, Joan, Subirana, Juan A, Campos, J Lourdes

“…We present here for the first time the crystal structure of an AT-hook domain. We show the structure of an AT-hook of the ubiquitous nuclear protein HMGA1,…”
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New features of vault architecture and dynamics revealed by novel refinement using the deformable elastic network approach by Casañas, Arnau, Querol-Audí, Jordi, Guerra, Pablo, Pous, Joan, Tanaka, Hideaki, Tsukihara, Tomitake, Verdaguer, Nuria, Fita, Ignasi

“…The vault particle, with a molecular weight of about 10 MDa, is the largest ribonucleoprotein that has been described. The X‐ray structure of intact rat vault…”
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Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1 by Jaime Guillén, Cristina Ferrer-Orta, Mònica Buxaderas, Dolores Pérez-Sánchez, Marta Guerrero-Valero, Ginés Luengo-Gil, Joan Pous, Pablo Guerra, Juan C. Gómez-Fernández, Nuria Verdaguer, Senena Corbalán-García

“…Proteins containing C2 domains are the sensors for Ca(2+) and PI(4,5)P2 in a myriad of secretory pathways. Here, the use of a free-mounting system has enabled…”
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The 2.6-Angstrom Structure of Infectious Bursal Disease Virus-Derived T=1 Particles Reveals New Stabilizing Elements of the Virus Capsid by GARRIGA, Damia, QUEROL-AUDI, Jordi, ABAITUA, Fernando, SAUGAR, Irene, POUS, Joan, VERDAGUER, Nuria, CASTON, José R, RODRIGUEZ, José F

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structural Peptides of a Nonenveloped Virus Are Involved in Assembly and Membrane Translocation by CHEVALIER, Christophe, GALLOUX, Marie, POUS, Joan, HENRY, Céline, DENIS, Jérome, DA COSTA, Bruno, NAVAZA, Jorge, LEPAULT, Jean, DELMAS, Bernard

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Inside Cover: Discovery and Mechanistic Elucidation of NQO1‐Bioactivatable Small Molecules That Overcome Resistance to Degraders (Angew. Chem. Int. Ed. 12/2024) by Barbosa, Bárbara M. G., Sfyaki, Aikaterini, Rafael, Sergi, José‐Duran, Ferran, Pous, Joan, Sánchez‐Zarzalejo, Carolina, Perez‐Lopez, Carles, Vilanova, Mar, Cigler, Marko, Gay, Marina, Vilaseca, Marta, Winter, Georg E., Riera, Antoni, Mayor‐Ruiz, Cristina

“…Multiomics‐driven elucidation of RBS‐10 as a prodrug bioactivated by the enzyme NQO1 is reported by Antoni Riera, Cristina Mayor‐Ruiz et al. in their Research…”
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Discovery and Mechanistic Elucidation of NQO1‐Bioactivatable Small Molecules That Overcome Resistance to Degraders by Barbosa, Bárbara M. G., Sfyaki, Aikaterini, Rafael, Sergi, José‐Duran, Ferran, Pous, Joan, Sánchez‐Zarzalejo, Carolina, Perez‐Lopez, Carles, Vilanova, Mar, Cigler, Marko, Gay, Marina, Vilaseca, Marta, Winter, Georg E., Riera, Antoni, Mayor‐Ruiz, Cristina

“…Degraders hold the promise to efficiently inactivate previously intractable disease‐relevant targets. Unlike traditional inhibitors, degraders act…”
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Detailed architecture of a DNA translocating machine: the high-resolution structure of the bacteriophage φ29 connector particle 1 1Edited by R. Huber by Guasch, Alicia, Pous, Joan, Ibarra, Borja, Gomis-Rüth, F.Xavier, Valpuesta, José Marı́a, Sousa, Natalia, Carrascosa, José L, Coll, Miquel

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Using a partial atomic model from medium‐resolution cryo‐EM to solve a large crystal structure by Fàbrega-Ferrer, Montserrat, Cuervo, Ana, Fernández, Francisco J., Machón, Cristina, Pérez-Luque, Rosa, Pous, Joan, Vega, M. Cristina, Carrascosa, José L., Coll, Miquel

“…Medium‐resolution cryo‐electron microscopy maps, in particular when they include a significant number of α‐helices, may allow the building of partial models…”
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Three-dimensional crystal structure of human eosinophil cationic protein (RNase 3) at 1.75 Å resolution11Edited by R. Huber by Mallorquı́-Fernández, Goretti, Pous, Joan, Peracaula, Rosa, Aymamı́, Joan, Maeda, Takashi, Tada, Hiroko, Yamada, Hidenori, Seno, Masaharu, de Llorens, Rafael, Gomis-Rüth, F.Xavier, Coll, Miquel

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Innentitelbild: Discovery and Mechanistic Elucidation of NQO1‐Bioactivatable Small Molecules That Overcome Resistance to Degraders (Angew. Chem. 12/2024) by Barbosa, Bárbara M. G., Sfyaki, Aikaterini, Rafael, Sergi, José‐Duran, Ferran, Pous, Joan, Sánchez‐Zarzalejo, Carolina, Perez‐Lopez, Carles, Vilanova, Mar, Cigler, Marko, Gay, Marina, Vilaseca, Marta, Winter, Georg E., Riera, Antoni, Mayor‐Ruiz, Cristina

“…Multiomics‐driven elucidation of RBS‐10 as a prodrug bioactivated by the enzyme NQO1 is reported by Antoni Riera, Cristina Mayor‐Ruiz et al. in their Research…”
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Discovery and Mechanistic Elucidation of NQO1‐Bioactivatable Small Molecules That Overcome Resistance to Degraders by Barbosa, Bárbara M. G., Sfyaki, Aikaterini, Rafael, Sergi, José‐Duran, Ferran, Pous, Joan, Sánchez‐Zarzalejo, Carolina, Perez‐Lopez, Carles, Vilanova, Mar, Cigler, Marko, Gay, Marina, Vilaseca, Marta, Winter, Georg E., Riera, Antoni, Mayor‐Ruiz, Cristina

“…Degraders hold the promise to efficiently inactivate previously intractable disease‐relevant targets. Unlike traditional inhibitors, degraders act…”
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Structure of the Triatoma virus capsid by Squires, Gaëlle, Pous, Joan, Agirre, Jon, Rozas-Dennis, Gabriela S., Costabel, Marcelo D., Marti, Gerardo A., Navaza, Jorge, Bressanelli, Stéphane, Guérin, Diego M. A., Rey, Felix A.

“…The members of the Dicistroviridae family are non‐enveloped positive‐sense single‐stranded RNA (+ssRNA) viruses pathogenic to beneficial arthropods as well as…”
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Structure of the N-terminal domain of the protein Expansion: an `Expansion' to the Smad MH2 fold by Beich-Frandsen, Mads, Aragón, Eric, Llimargas, Marta, Benach, Jordi, Riera, Antoni, Pous, Joan, Macias, Maria J.

“…Gene‐expression changes observed in Drosophila embryos after inducing the transcription factor Tramtrack led to the identification of the protein Expansion…”
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Polymorphic crystal structures of an all-AT DNA dodecamer by Acosta-Reyes, Francisco J., Subirana, Juan A., Pous, Joan, Sánchez-Giraldo, Raquel, Condom, Núria, Baldini, Roberto, Malinina, Lucy, Campos, J. Lourdes

“…ABSTRACT In this work, we explore the influence of different solvents and ions on the crystallization behavior of an all‐AT dodecamer d(AATAAATTTATT)2 In all…”
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The interaction of manganese ions with DNA by Millonig, Hans, Pous, Joan, Gouyette, Catherine, Subirana, Juan A., Campos, J. Lourdes

“…We present the structure of the duplex formed by a fragment of auto-complementary DNA with the sequence d(CGTTAATTAACG). The structure was determined by X-ray…”
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