Search Results - "Jo M Wilmshurst"

The ILAE classification of seizures and the epilepsies: Modification for seizures in the neonate. Position paper by the ILAE Task Force on Neonatal Seizures by Pressler, Ronit M., Cilio, Maria Roberta, Mizrahi, Eli M., Moshé, Solomon L., Nunes, Magda L., Plouin, Perrine, Vanhatalo, Sampsa, Yozawitz, Elissa, de Vries, Linda S., Puthenveettil Vinayan, Kollencheri, Triki, Chahnez C., Wilmshurst, Jo M., Yamamoto, Hitoshi, Zuberi, Sameer M.

“…Seizures are the most common neurological emergency in the neonatal period and in contrast to those in infancy and childhood, are often provoked seizures with…”
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Subacute sclerosing panencephalitis: clinical phenotype, epidemiology, and preventive interventions by Mekki, Mohammed, Eley, Brian, Hardie, Diana, Wilmshurst, Jo M

“…Subacute sclerosing panencephalitis (SSPE) is a preventable condition reported in 6.5 to 11 per 100 000 cases of measles, and highest in children who…”
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Timing of referral to evaluate for epilepsy surgery: Expert Consensus Recommendations from the Surgical Therapies Commission of the International League Against Epilepsy by Jehi, Lara, Jette, Nathalie, Kwon, Churl‐Su, Josephson, Colin B., Burneo, Jorge G., Cendes, Fernando, Sperling, Michael R., Baxendale, Sallie, Busch, Robyn M., Triki, Chahnez Charfi, Cross, J. Helen, Ekstein, Dana, Englot, Dario J., Luan, Guoming, Palmini, Andre, Rios, Loreto, Wang, Xiongfei, Roessler, Karl, Rydenhag, Bertil, Ramantani, Georgia, Schuele, Stephan, Wilmshurst, Jo M., Wilson, Sarah, Wiebe, Samuel

“…Epilepsy surgery is the treatment of choice for patients with drug‐resistant seizures. A timely evaluation for surgical candidacy can be life‐saving for…”
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Clinical practice applicability and relevance to non-specialists of a paediatric EEG online learning tool by Kander, Veena, Hardman, Joanne, Wilmshurst, Jo M

“…Paediatric electroencephalography (EEG) training is inadequate amongst healthcare practitioners and technicians managing children with epilepsy in sub-Saharan…”
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Editorial: Insights in pediatric neurology: 2021 by Ni, Hong, Striano, Pasquale, Wilmshurst, Jo M.

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Dravet syndrome: A systematic literature review of the illness burden by Strzelczyk, Adam, Lagae, Lieven, Wilmshurst, Jo M, Brunklaus, Andreas, Striano, Pasquale, Rosenow, Felix, Schubert‐Bast, Susanne

“…We performed a systematic literature review and narrative synthesis according to a pre‐registered protocol (Prospero: CRD42022376561) to identify the evidence…”
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Establishing criteria for pediatric epilepsy surgery center levels of care: Report from the ILAE Pediatric Epilepsy Surgery Task Force by Gaillard, William D., Jette, Nathalie, Arnold, Susan T., Arzimanoglou, Alexis, Braun, Kees P. J., Cukiert, Arthur, Dick, Alexander, Harvey, A. Simon, Jacobs, Julia, Rydenhag, Bertil, Udani, Vrajesh, Wilmshurst, Jo M., Cross, J. Helen, Jayakar, Prasanna

“…Presurgical evaluation and surgery in the pediatric age group are unique in challenges related to caring for the very young, range of etiologies, choice of…”
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Hereditary peripheral neuropathies of childhood: An overview for clinicians by Wilmshurst, Jo M, Ouvrier, Robert

“…Abstract This review focuses on the “pure” hereditary peripheral neuropathies where peripheral nerve disease is the main manifestation and does not address…”
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A Comparison of Parenteral Phenobarbital vs. Parenteral Phenytoin as Second-Line Management for Pediatric Convulsive Status Epilepticus in a Resource-Limited Setting by Burman, Richard J, Ackermann, Sally, Shapson-Coe, Alexander, Ndondo, Alvin, Buys, Heloise, Wilmshurst, Jo M

“…Pediatric convulsive status epilepticus (CSE) which is refractory to first-line benzodiazepines is a significant clinical challenge, especially within…”
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Neuropsychiatric and Neurocognitive Manifestations in HIV-Infected Children Treated With Efavirenz in South Africa-A Retrospective Case Series by Hammond, Charles K, Eley, Brian, Ing, Natalia, Wilmshurst, Jo M

“…Efavirenz is associated with transient neuropsychiatric manifestations but the impact on neurocognition in children is unknown. Genetically slow metabolizers…”
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The mutational profile in a South African cohort with inherited neuropathies and spastic paraplegia by Mahungu, Amokelani C., Steyn, Elizabeth, Floudiotis, Niki, Wilson, Lindsay A., Vandrovcova, Jana, Reilly, Mary M., Record, Christopher J., Benatar, Michael, Wu, Gang, Raga, Sharika, Wilmshurst, Jo M., Naidu, Kireshnee, Hanna, Michael, Nel, Melissa, Heckmann, Jeannine M.

“…Limited diagnostics are available for inherited neuromuscular diseases (NMD) in South Africa and (excluding muscle disease) are mainly aimed at the most…”
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Medical treatment in infants and young children with epilepsy: Off‐label use of antiseizure medications. Survey Report of ILAE Task Force Medical Therapies in Children by Sourbron, Jo, Auvin, Stéphane, Arzimanoglou, Alexis, Cross, J. Helen, Hartmann, Hans, Pressler, Ronit, Riney, Kate, Sugai, Kenji, Wilmshurst, Jo M., Yozawitz, Elissa, Lagae, Lieven

“…Objective Antiseizure medications (ASMs) remain the mainstay of epilepsy treatment. These ASMs have mainly been tested in trials in adults with epilepsy, which…”
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ICNA and the Global Regional Initiative Program: Aligning with IGAP towards providing child neurology services where they are most needed by Wilmshurst, Jo M.

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Skin cells for use in an alternate diagnostic method for Duchenne muscular dystrophy by Tyers, Lynn, Davids, Lester M., Wilmshurst, Jo M., Esterhuizen, Alina I.

“…•Confirmed the feasibility of cultured skin cells for RNA-based diagnosis of DMD.•Skin biopsies are safer and cheaper than muscle biopsies for RNA-based…”
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RyR1 Deficiency in Congenital Myopathies Disrupts Excitation-Contraction Coupling by Zhou, Haiyan, Rokach, Ori, Feng, Lucy, Munteanu, Iulia, Mamchaoui, Kamel, Wilmshurst, Jo M., Sewry, Caroline, Manzur, Adnan Y., Pillay, Komala, Mouly, Vincent, Duchen, Michael, Jungbluth, Heinz, Treves, Susan, Muntoni, Francesco

“…ABSTRACT In skeletal muscle, excitation–contraction (EC) coupling is the process whereby the voltage‐gated dihydropyridine receptor (DHPR) located on the…”
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Clinical Application of Epilepsy Genetics in Africa: Is Now the Time? by Esterhuizen, Alina I, Carvill, Gemma L, Ramesar, Rajkumar S, Kariuki, Symon M, Newton, Charles R, Poduri, Annapurna, Wilmshurst, Jo M

“…Over 80% of people with epilepsy live in low- to middle-income countries where epilepsy is often undiagnosed and untreated due to limited resources and poor…”
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Neurologic Complications of Pediatric Human Immunodeficiency Virus: Implications for Clinical Practice and Management Challenges in the African Setting by Donald, Kirsten Ann, MPhil (Paed Neuro), Hoare, Jackie, MPhil, Eley, Brian, MBChB, Wilmshurst, Jo M., MD

“…Approximately 3.4 million children worldwide are affected with human immunodeficiency virus (HIV)/AIDS with more than 90% of them residing in sub-Saharan…”
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Peripheral nerve disease secondary to systemic conditions in children by Wilmshurst, Jo M., Ouvrier, Robert A., Ryan, Monique M.

“…This review is an overview of systemic conditions that can be associated with peripheral nervous system dysfunction. Children may present with neuropathic…”
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The Challenges of Managing Children With Epilepsy in Africa by Wilmshurst, Jo M., MBBS, MRCP, FCP, MD, Kakooza-Mwesige, Angelina, MMED, Newton, Charles R., MD

“…Children with epilepsy who reside in the African continent are faced with some of the greatest challenges of receiving adequate care. The burden of disease is…”
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International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions by Specchio, Nicola, Wirrell, Elaine C., Scheffer, Ingrid E., Nabbout, Rima, Riney, Kate, Samia, Pauline, Guerreiro, Marilisa, Gwer, Sam, Zuberi, Sameer M., Wilmshurst, Jo M., Yozawitz, Elissa, Pressler, Ronit, Hirsch, Edouard, Wiebe, Sam, Cross, Helen J., Perucca, Emilio, Moshé, Solomon L., Tinuper, Paolo, Auvin, Stéphane

“…The 2017 International League Against Epilepsy classification has defined a three‐tier system with epilepsy syndrome identification at the third level…”
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