Search Results - "Jo Lynne Raymond"
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Comparative virulence of three different strains of Burkholderia pseudomallei in an aerosol non-human primate model
Published in PLoS neglected tropical diseases (11-02-2021)“…Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is a major cause of sepsis and mortality in endemic regions of Southeast Asia and…”
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2
Dose Response of MARV/Angola Infection in Cynomolgus Macaques following IM or Aerosol Exposure
Published in PloS one (28-09-2015)“…Marburg virus infection in humans causes a hemorrhagic disease with a high case fatality rate. Countermeasure development requires the use of…”
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3
Smallpox lesion characterization in placebo-treated and tecovirimat-treated macaques using traditional and novel methods
Published in PLoS pathogens (01-02-2024)“…Smallpox was the most rampant infectious disease killer of the 20th century, yet much remains unknown about the pathogenesis of the variola virus. Using…”
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4
Effect of Monkeypox Virus Preparation on the Lethality of the Intravenous Cynomolgus Macaque Model
Published in Viruses (01-08-2022)“…For over two decades, researchers have sought to improve smallpox vaccines and also develop therapies to ensure protection against smallpox or smallpox-like…”
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5
Impact of Phlebotomine Sand Flies on U.S. Military Operations at Tallil Air Base, Iraq: 1. Background, Military Situation, and Development of a “Leishmaniasis Control Program”
Published in Journal of medical entomology (01-07-2006)“…One of the most significant modern day efforts to prevent and control an arthropod-borne disease during a military deployment occurred when a team of U.S…”
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Retrospective detection of monkeypox virus in the testes of nonhuman primate survivors
Published in Nature microbiology (01-12-2022)“…Close contact through sexual activity has been associated with the spread of monkeypox virus (MPXV) in the ongoing, global 2022 epidemic. However, it remains…”
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Characterization of Ebola Virus Disease (EVD) in Rhesus Monkeys for Development of EVD Therapeutics
Published in Viruses (13-01-2020)“…Recent Ebola virus (EBOV) outbreaks in West Africa and the Democratic Republic of the Congo have highlighted the urgent need for approval of medical…”
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A spontaneous mutation in kdsD, a biosynthesis gene for 3 Deoxy-D-manno-Octulosonic Acid, occurred in a ciprofloxacin resistant strain of Francisella tularensis and caused a high level of attenuation in murine models of tularemia
Published in PloS one (01-03-2017)“…Francisella tularensis, a gram-negative facultative intracellular bacterial pathogen, is the causative agent of tularemia and able to infect many mammalian…”
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9
Progression of pathogenic events in cynomolgus macaques infected with variola virus
Published in PloS one (06-10-2011)“…Smallpox, caused by variola virus (VARV), is a devastating human disease that affected millions worldwide until the virus was eradicated in the 1970 s…”
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10
Severe Encephalitis in Cynomolgus Macaques Exposed to Aerosolized Eastern Equine Encephalitis Virus
Published in The Journal of infectious diseases (01-08-2007)“…Cynomolgus macaques exposed to an aerosol containing a virulent strain of eastern equine encephalitis (EEE) virus developed neurological signs indicating…”
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11
Characterization of the Cynomolgus Macaque Model of Marburg Virus Disease and Assessment of Timing for Therapeutic Treatment Testing
Published in Viruses (28-11-2023)“…Marburg virus (MARV) causes severe disease and high mortality in humans. The objective of this study was to characterize disease manifestations and…”
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12
Smallpox lesion characterization in placebo-treated and tecovirimat-treated macaques using traditional and novel methods
Published in PLoS pathogens (01-02-2024)Get full text
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13
Development of a coronavirus disease 2019 nonhuman primate model using airborne exposure
Published in PloS one (02-02-2021)“…Airborne transmission is predicted to be a prevalent route of human exposure with SARS-CoV-2. Aside from African green monkeys, nonhuman primate models that…”
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14
Impact of Phlebotomine Sand Flies on U.S. Military Operations at Tallil Air Base, Iraq: 1. Background, Military Situation, and Development of a “Leishmaniasis Control Program”
Published in Journal of medical entomology (01-07-2006)“…One of the most significant modern day efforts to prevent and control an arthropod-borne disease during a military deployment occurred when a team of U.S…”
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15
Randomized, Double-blind, Placebo-controlled, Dose-response, and Preclinical Safety Study of Transforaminal Epidural Etanercept for the Treatment of Sciatica
Published in Anesthesiology (Philadelphia) (01-05-2009)“…Recent evidence implicates the inflammatory cytokine tumor necrosis factor as a major cause of radiculopathy. Yet, whereas open-label studies with systemically…”
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16
A spontaneous mutation in kdsD, a biosynthesis gene for 3 Deoxy-.sub.D-manno-Octulosonic Acid, occurred in a ciprofloxacin resistant strain of Francisella tularensis and caused a high level of attenuation in murine models of tularemia
Published in PloS one (22-03-2017)“…Francisella tularensis, a gram-negative facultative intracellular bacterial pathogen, is the causative agent of tularemia and able to infect many mammalian…”
Get full text
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17
A SARS-CoV-2 Spike Ferritin Nanoparticle Vaccine Is Protective and Promotes a Strong Immunological Response in the Cynomolgus Macaque Coronavirus Disease 2019 (COVID-19) Model
Published in Vaccines (Basel) (04-05-2022)“…The COVID-19 pandemic has had a staggering impact on social, economic, and public health systems worldwide. Vaccine development and mobilization against…”
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18
Effect of Teriparatide [rhPTH(1,34)] and Calcitonin on Intertransverse Process Fusion in a Rabbit Model
Published in Spine (Philadelphia, Pa. 1976) (15-01-2010)“…Randomized, double-blinded, placebo controlled animal study. To evaluate the effect of teriparatide and calcitonin after an intertransverse process spinal…”
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19
3-Deazaneplanocin A induces massively increased interferon-α production in Ebola virus-infected mice
Published in Antiviral research (01-07-2002)“…3-Deazaneplanocin A, an analog of adenosine, is a potent inhibitor of Ebola virus replication. A single dose early in infection prevents illness and death in…”
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20
Impact of Phlebotomine Sand Flies on U.S. Military Operations at Tallil Air Base, Iraq: 1. Background, Military Situation, and Development of a "Leishmaniasis Control Program"
Published in Journal of medical entomology (01-07-2006)“…One of the most significant modern day efforts to prevent and control an arthropod-borne disease during a military deployment occurred when a team of U.S…”
Get full text
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