Search Results - "João Santana Silva"
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IL-18 triggered by the Nlrp3 inflammasome induces host innate resistance in a pulmonary model of fungal infection
Published in The Journal of immunology (1950) (01-05-2015)“…Pathogens are sensed by innate immune receptors that initiate an efficient adaptive immune response upon activation. The elements of the innate immune…”
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NLR and Intestinal Dysbiosis-Associated Inflammatory Illness: Drivers or Dampers?
Published in Frontiers in immunology (11-08-2020)“…The intestinal microbiome maintains a close relationship with the host immunity. This connection fosters a health state by direct and indirect mechanisms…”
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Th17-Inducing Cytokines IL-6 and IL-23 Are Crucial for Granuloma Formation during Experimental Paracoccidioidomycosis
Published in Frontiers in immunology (21-08-2017)“…Paracoccidioidomycosis (PCM), a chronic granulomatous disease caused by the thermally dimorphic fungus and , has the highest mortality rate among systemic…”
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HLA-G, cytokines, and cytokine receptors in the non-aggressive basal cell carcinoma microenvironment
Published in Archives of Dermatological Research (01-04-2022)“…Non-aggressive basal cell carcinoma (BCC) growth is slow and might be mediated by the immune system. This study analysed the human leukocyte antigen (HLA)-G…”
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Quantification of parasite burden of Trypanosoma cruzi and identification of Discrete Typing Units (DTUs) in blood samples of Latin American immigrants residing in Barcelona, Spain
Published in PLoS neglected tropical diseases (01-06-2020)“…Background Trypanosoma cruzi has a high genetic and biological diversity and has been subdivided into seven genetic lineages, named TcI-TcVI and TcBat. DTUs…”
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Synonymous mutation rs1129293 is associated with PIK3CG expression and PI3Kγ activation in patients with chronic Chagas cardiomyopathy
Published in Immunobiology (1979) (01-09-2022)“…[Display omitted] Single nucleotide polymorphisms (SNPs) that do not change the composition of amino acids and cause synonymous mutations (sSNPs) were…”
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Expression of B lymphocyte-induced maturation protein 1 (Blimp-1) in keratinocyte and cytokine signalling drives human Th17 response in psoriasis
Published in Archives of dermatological research (01-04-2023)“…Transcriptional factor B lymphocyte-induced maturation protein 1 (Blimp-1) is pivotally implicated in T helper 17 (Th17) cell differentiation. This study…”
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TLR3 is required for survival following Coxsackievirus B3 infection by driving T lymphocyte activation and polarization: The role of dendritic cells
Published in PloS one (03-10-2017)“…Type B coxsackievirus (CVB) is a common cause of acute and chronic myocarditis, meningitis and pancreatitis, often leading to heart failure and pancreatic…”
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Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity
Published in British journal of pharmacology (01-05-2010)“…Background and purpose: The discovery of the pharmacological functions of nitric oxide has led to the development of NO donor compounds as therapeutic agents…”
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Complexation of the anti-Trypanosoma cruzi Drug Benznidazole Improves Solubility and Efficacy
Published in Journal of medicinal chemistry (24-07-2008)“…The ruthenium complex, trans-[Ru(Bz)(NH3)4SO2](CF3SO3)2 1, Bz = benznidazole (N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide), is more hydrosoluble and more…”
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11
Modulation of ERG Genes Expression in Clinical Isolates of Candida tropicalis Susceptible and Resistant to Fluconazole and Itraconazole
Published in Mycopathologia (1975) (01-08-2020)“…Candida tropicalis is a non- albicans Candida specie that causes candidosis in several countries, including Brazil. However, little is known about the…”
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Evidences of the cooperative role of the chemokines CCL3, CCL4 and CCL5 and its receptors CCR1+ and CCR5+ in RANKL+ cell migration throughout experimental periodontitis in mice
Published in Bone (New York, N.Y.) (01-04-2010)“…Abstract Periodontal disease (PD) is characterized by the inflammatory bone resorption in response to the bacterial challenge, in a host response that involves…”
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Characterization of CD4+CD25+ natural regulatory T cells in the inflammatory infiltrate of human chronic periodontitis
Published in Journal of leukocyte biology (01-07-2008)“…Periodontitis is an infectious disease, where putative periodontopathogens trigger chronic inflammatory and immune responses against periodontal structures, in…”
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Enhanced programmed death 1 (PD-1) and PD-1 ligand (PD-L1) expression in patients with actinic cheilitis and oral squamous cell carcinoma
Published in Cancer Immunology, Immunotherapy (01-07-2011)“…PD-1 and PD-L1 can be involved in tumor escape, and little is known about the role of these molecules in oral tumors or pre-malignant lesions. In the present…”
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Differential expression of osteoblast and osteoclast chemmoatractants in compression and tension sides during orthodontic movement
Published in Cytokine (Philadelphia, Pa.) (01-06-2008)“…Orthodontic tooth movement is achieved by the remodeling of alveolar bone in response to mechanical loading, and is supposed to be mediated by several host…”
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Inhibition of Leukocyte Rolling by Nitric Oxide during Sepsis Leads to Reduced Migration of Active Microbicidal Neutrophils
Published in Infection and Immunity (01-07-2002)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Increased Activities of Cardiac Matrix Metalloproteinases Matrix Metalloproteinase (MMP)-2 and MMP-9 Are Associated with Mortality during the Acute Phase of Experimental Trypanosoma cruzi Infection
Published in The Journal of infectious diseases (15-05-2008)“…The strong inflammatory reaction that occurs in the heart during the acute phase of Trypanosoma cruzi infection is modulated by cytokines and chemokines…”
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18
Xenogeneic mesenchymal stem cell biocurative improves skin wounds healing in diabetic mice by increasing mast cells and the regenerative profile
Published in Regenerative therapy (01-03-2023)“…Diabetes mellitus (DM) is a chronic disease and a major cause of mortality and morbidity worldwide. The hyperglycemia caused by DM induces micro and…”
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Patients with oral squamous cell carcinoma are characterized by increased frequency of suppressive regulatory T cells in the blood and tumor microenvironment
Published in Cancer Immunology, Immunotherapy (01-06-2010)“…Oral squamous cell carcinoma (OSCC) is a cancerous lesion with high incidence worldwide. The immunoregulatory events leading to OSCC persistence remain to be…”
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5-Lipoxygenase Activity Increases Susceptibility to Experimental Paracoccidioides brasiliensis Infection
Published in Infection and Immunity (01-04-2013)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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