Search Results - "Jo, Seong Lae"
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Neuroprotective Effects of Ecklonia cava in a Chronic Neuroinflammatory Disease Model
Published in Nutrients (21-04-2023)“…Inflammation is a natural defense mechanism against noxious stimuli, but chronic inflammation can lead to various chronic diseases. Neuroinflammation in the…”
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2
Curcumae Radix Decreases Neurodegenerative Markers through Glycolysis Decrease and TCA Cycle Activation
Published in Nutrients (11-04-2022)“…Neurodegenerative diseases (ND) are being increasingly studied owing to the increasing proportion of the aging population. Several potential compounds are…”
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3
Progesterone receptor membrane component 1 reduces cardiac steatosis and lipotoxicity via activation of fatty acid oxidation and mitochondrial respiration
Published in Scientific reports (22-04-2021)“…Obesity is implicated in cardiovascular disease and heart failure. When fatty acids are transported to and not adequately oxidized in cardiac cells, they…”
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Progesterone Receptor Membrane Component 1 Regulates Cellular Stress Responses and Inflammatory Pathways in Chronic Neuroinflammatory Conditions
Published in Antioxidants (01-02-2024)“…Alzheimer's disease (AD) is the leading cause of dementia and is one of the neurodegenerative diseases that are caused by neuronal death due to various…”
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Curcumae radix Reduces Endoplasmic Reticulum Stress in Mice with Chronic Neuroinflammation
Published in Biomedicines (26-07-2023)“…Endoplasmic reticulum (ER) stress is a condition in which the ER protein-folding machinery is impaired, leading to the accumulation of improperly folded…”
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Hepatic progesterone receptor membrane component 1 attenuates ethanol-induced liver injury by reducing acetaldehyde production and oxidative stress
Published in American journal of physiology: Gastrointestinal and liver physiology (01-06-2023)“…Alcohol-associated liver disease (ALD) is caused by excessive abuse of alcohol. One of the most representative causes of ALD is the action of acetaldehyde…”
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Dietary Intake of 17α-Ethinylestradiol Promotes HCC Progression in Humanized Male Mice Expressing Sex Hormone-Binding Globulin
Published in International journal of molecular sciences (22-11-2021)“…Hepatocellular carcinoma (HCC) is a male-oriented malignancy; its progression is affected by sex hormones. 17α-ethinylestradiol (EE2) is a synthetic estrogen…”
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Hepatic LKB1 Reduces the Progression of Non-Alcoholic Fatty Liver Disease via Genomic Androgen Receptor Signaling
Published in International journal of molecular sciences (01-08-2021)“…The incidence of non-alcoholic fatty liver disease (NAFLD) increases in males aged >45 years, which indicates that androgens are associated with the…”
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Letrozole Accelerates Metabolic Remodeling through Activation of Glycolysis in Cardiomyocytes: A Role beyond Hormone Regulation
Published in International journal of molecular sciences (04-01-2022)“…Estrogen receptor-positive (ER+) breast cancer patients are recommended hormone therapy as a primary adjuvant treatment after surgery. Aromatase inhibitors…”
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Absence of progesterone receptor membrane component 1 reduces migration and metastasis of breast cancer
Published in Cell communication and signaling (08-04-2021)“…Progesterone receptor membrane component 1 (Pgrmc1) is a non-classical progesterone receptor associated with the development of the mammary gland and…”
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The Improvement Effect of D-Chiro-Inositol and Ecklonia cava K. in the Rat Model of Polycystic Ovarian Syndrome
Published in Frontiers in pharmacology (19-07-2022)“…Introduction: Polycystic Ovarian Syndrome (PCOS) is known to be an endocrine state that is characterized by oligomenorrhea, hyperandrogenism, and highly cystic…”
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Loss of PGRMC1 Delays the Progression of Hepatocellular Carcinoma via Suppression of Pro-Inflammatory Immune Responses
Published in Cancers (18-05-2021)“…Pgrmc1 is a non-canonical progesterone receptor related to the lethality of various types of cancer. PGRMC1 has been reported to exist in co-precipitated…”
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Neuroprotective Effects of IEcklonia cava/I in a Chronic Neuroinflammatory Disease Model
Published in Nutrients (01-04-2023)“…Inflammation is a natural defense mechanism against noxious stimuli, but chronic inflammation can lead to various chronic diseases. Neuroinflammation in the…”
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The aqueous fraction of Castanea crenata inner shell extract reduces obesity and intramuscular lipid accumulation via induction of mitochondrial respiration and fatty acid oxidation in muscle
Published in Phytomedicine (Stuttgart) (01-04-2022)“…Skeletal muscle is responsible for free fatty acid (FFA) disposal via mitochondrial respiration and fatty acid oxidation (FAO). Obesity triggers high levels of…”
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ICurcumae radix/I Reduces Endoplasmic Reticulum Stress in Mice with Chronic Neuroinflammation
Published in Biomedicines (01-07-2023)“…Endoplasmic reticulum (ER) stress is a condition in which the ER protein-folding machinery is impaired, leading to the accumulation of improperly folded…”
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Suppressed estrogen supply via extra-ovarian progesterone receptor membrane component 1 in menopause
Published in Journal of biomedical research (29-01-2021)“…In post-menopausal women, intra-mammary estrogen, which is converted from extra-ovarian estrone (E1), promotes the growth of breast cancer. Since the aromatase…”
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