Search Results - "Jo, Sang Yong"
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The Medial Prefrontal Cortex Is Involved in Spatial Memory Retrieval under Partial-Cue Conditions
Published in The Journal of neuroscience (05-12-2007)“…Brain circuits involved in pattern completion, or retrieval of memory from fragmented cues, were investigated. Using different versions of the Morris water…”
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Roundabout receptor 2 maintains inhibitory control of the adult midbrain
Published in eLife (10-04-2017)“…The maintenance of excitatory and inhibitory balance in the brain is essential for its function. Here we find that the developmental axon guidance receptor…”
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Conditioned flight response in female rats to naturalistic threat is estrous-cycle dependent
Published in Scientific reports (28-11-2023)“…Despite the prevalent expression of freezing behavior following Pavlovian fear conditioning, a growing body of literature suggests potential sex differences in…”
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Neural mechanism of acute stress regulation by trace aminergic signalling in the lateral habenula in male mice
Published in Nature communications (27-04-2023)“…Stress management is necessary for vertebrate survival. Chronic stress drives depression by excitation of the lateral habenula (LHb), which silences…”
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Transcranial focused ultrasound stimulation in the infralimbic cortex facilitates extinction of conditioned fear in rats
Published in Brain stimulation (01-03-2024)“…Transcranial focused ultrasound (tFUS) neuromodulation emerges as a promising non-invasive approach for improving neurological conditions. Extinction of…”
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Clinical outcomes of Dieulafoy's lesion compared with peptic ulcer in upper gastrointestinal bleeding
Published in Journal of gastroenterology and hepatology (01-06-2023)“…Background and Aim Although Dieulafoy's lesion (DL) is an important cause of nonvariceal upper gastrointestinal (GI) bleeding, few studies have investigated…”
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Heterogenous effect of early adulthood stress on cognitive aging and synaptic function in the dentate gyrus
Published in Frontiers in molecular neuroscience (04-04-2024)“…Cognitive aging widely varies among individuals due to different stress experiences throughout the lifespan and vulnerability of neurocognitive mechanisms. To…”
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Memory retrieval in response to partial cues requires NMDA receptor-dependent neurotransmission in the medial prefrontal cortex
Published in Neurobiology of learning and memory (01-03-2014)“…•NMDAR blockade in the mPFC did not affect retrieval of a spatial memory in the original environment.•NMDAR blockade in the mPFC selectively impaired memory…”
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Inositol 1,4,5-Trisphosphate 3-Kinase A Functions As a Scaffold for Synaptic Rac Signaling
Published in The Journal of neuroscience (04-11-2009)“…Activity-dependent alterations of synaptic contacts are crucial for synaptic plasticity. The formation of new dendritic spines and synapses is known to require…”
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Mind bomb-1 is an essential modulator of long-term memory and synaptic plasticity via the Notch signaling pathway
Published in Molecular brain (30-10-2012)“…Notch signaling is well recognized as a key regulator of the neuronal fate during embryonic development, but its function in the adult brain is still largely…”
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Dopamine Neurons Reflect the Uncertainty in Fear Generalization
Published in Neuron (Cambridge, Mass.) (21-11-2018)“…Generalized fear is a maladaptive behavior in which non-threatening stimuli elicit a fearful response. Here, we demonstrate that discrimination between…”
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Synergy of Distinct Dopamine Projection Populations in Behavioral Reinforcement
Published in Neuron (Cambridge, Mass.) (04-03-2020)“…Dopamine neurons of the ventral tegmental area (VTA) regulate reward association and motivation. It remains unclear whether there are distinct dopamine…”
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Activation of CGRP neurons in the parabrachial nucleus suppresses addictive behavior
Published in Proceedings of the National Academy of Sciences - PNAS (11-06-2024)“…Punishment such as electric shock or physical discipline employs a mixture of physical pain and emotional distress to induce behavior modification. However, a…”
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Prefrontal Regulation of Neuronal Activity in the Ventral Tegmental Area
Published in Cerebral cortex (New York, N.Y. 1991) (01-10-2016)“…Growing evidence indicates that midbrain dopamine (DA) cells integrate reward expectancy-related information from the prefrontal cortex to properly compute…”
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Perirhinal Cortex Is Necessary for Acquiring, but Not for Retrieving Object-Place Paired Association
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-02-2010)“…Remembering events frequently involves associating objects and their associated locations in space, and it has been implicated that the areas associated with…”
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Disconnection of the hippocampal-perirhinal cortical circuits severely disrupts object-place paired associative memory
Published in The Journal of neuroscience (21-07-2010)“…The hippocampus and the perirhinal cortex (PR) are reciprocally connected both directly and indirectly via the entorhinal cortex. Although it has been…”
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Lesions of the lateral habenula facilitate active avoidance learning and threat extinction
Published in Behavioural brain research (01-02-2017)“…•LHb was damaged to study its role in avoidance and threat learning.•LHb lesions facilitated two-way active avoidance learning.•LHb lesions had no effects on…”
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Effects of prefrontal cortical inactivation on neural activity in the ventral tegmental area
Published in The Journal of neuroscience (08-05-2013)“…Dopamine (DA) cells have been suggested to signal discrepancies between expected and actual rewards in reinforcement learning. DA cells in the ventral…”
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Lack of Medial Prefrontal Cortex Activation Underlies the Immediate Extinction Deficit
Published in The Journal of neuroscience (20-01-2010)“…We conducted a series of experiments to investigate the neural basis of the immediate extinction deficit, the lack of extinction when the interval between fear…”
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