Search Results - "Jo, Norihide"

Platforms of in vivo genome editing with inducible Cas9 for advanced cancer modeling by Jo, Norihide, Sogabe, Yuko, Yamada, Yosuke, Ukai, Tomoyo, Kagawa, Harunobu, Mitsunaga, Kanae, Woltjen, Knut, Yamada, Yasuhiro

“…The emergence of clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 technology has dramatically advanced how we manipulate the genome…”
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Smarcb1 maintains the cellular identity and the chromatin landscapes of mouse embryonic stem cells by Sakakura, Megumi, Ohta, Sho, Yagi, Masaki, Tanaka, Akito, Norihide, Jo, Woltjen, Knut, Yamamoto, Takuya, Yamada, Yasuhiro

“…ES cell (ESC) identity is stably maintained through the coordinated regulation of transcription factors and chromatin structure. SMARCB1, also known as INI1,…”
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Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas by Komura, Shingo, Ito, Kenji, Ohta, Sho, Ukai, Tomoyo, Kabata, Mio, Itakura, Fumiaki, Semi, Katsunori, Matsuda, Yutaka, Hashimoto, Kyoichi, Shibata, Hirofumi, Sone, Masamitsu, Jo, Norihide, Sekiguchi, Kazuya, Ohno, Takatoshi, Akiyama, Haruhiko, Shimizu, Katsuji, Woltjen, Knut, Ozawa, Manabu, Toguchida, Junya, Yamamoto, Takuya, Yamada, Yasuhiro

“…Clear cell sarcoma (CCS) is a rare soft tissue sarcoma caused by the EWS/ATF1 fusion gene. Here, we established induced pluripotent stem cells (iPSCs) from…”
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Human Pluripotent Stem Cell-Derived Tumor Model Uncovers the Embryonic Stem Cell Signature as a Key Driver in Atypical Teratoid/Rhabdoid Tumor by Terada, Yukinori, Jo, Norihide, Arakawa, Yoshiki, Sakakura, Megumi, Yamada, Yosuke, Ukai, Tomoyo, Kabata, Mio, Mitsunaga, Kanae, Mineharu, Yohei, Ohta, Sho, Nakagawa, Masato, Miyamoto, Susumu, Yamamoto, Takuya, Yamada, Yasuhiro

“…Atypical teratoid/rhabdoid tumor (AT/RT), which harbors SMARCB1 mutation and exhibits a characteristic histology of rhabdoid cells, has a poor prognosis…”
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Aging and CMV Infection Affect Pre-existing SARS-CoV-2-Reactive CD8+ T Cells in Unexposed Individuals by Jo, Norihide, Zhang, Rui, Ueno, Hideki, Yamamoto, Takuya, Weiskopf, Daniela, Nagao, Miki, Yamanaka, Shinya, Hamazaki, Yoko

“…Age is a major risk factor for COVID-19 severity, and T cells play a central role in anti-SARS-CoV-2 immunity. Because SARS-CoV-2-cross-reactive T cells have…”
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Delayed CD4 +T-cell response in older adults is associated with reduced immunogenicity and reactogenicity after COVID-19 mRNA vaccination by Jo, Norihide, Hidaka, Yu, Kikuchi, Osamu, Fukahori, Masaru, Sawada, Takeshi, Aoki, Masahiko, Yamamoto, Masaki, Nagao, Miki, Morita, Satoshi, Nakajima, Takako E, Muto, Manabu, Hamazaki, Yoko

“…While the newly developed COVID-19 mRNA vaccines are highly effective, characteristics of the immune response after the vaccination and its association with…”
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Effect of ABO Blood Group Incompatibility on the Outcome of Single-Unit Cord Blood Transplantation after Myeloablative Conditioning by Konuma, Takaaki, Kato, Seiko, Ooi, Jun, Oiwa-Monna, Maki, Ebihara, Yasuhiro, Mochizuki, Shinji, Yuji, Koichiro, Ohno, Nobuhiro, Kawamata, Toyotaka, Jo, Norihide, Yokoyama, Kazuaki, Uchimaru, Kaoru, Tojo, Arinobu, Takahashi, Satoshi

“…Abstract ABO blood group incompatibility between donor and recipient has been associated with poor transplant outcomes in allogeneic hematopoietic stem cell…”
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Impaired CD4 + T cell response in older adults is associated with reduced immunogenicity and reactogenicity of mRNA COVID-19 vaccination by Jo, Norihide, Hidaka, Yu, Kikuchi, Osamu, Fukahori, Masaru, Sawada, Takeshi, Aoki, Masahiko, Yamamoto, Masaki, Nagao, Miki, Morita, Satoshi, Nakajima, Takako E, Muto, Manabu, Hamazaki, Yoko

“…Whether age-associated defects in T cells impact the immunogenicity and reactogenicity of mRNA vaccines remains unclear. Using a vaccinated cohort (n = 216),…”
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Author Correction: Impaired CD4 + T cell response in older adults is associated with reduced immunogenicity and reactogenicity of mRNA COVID-19 vaccination by Jo, Norihide, Hidaka, Yu, Kikuchi, Osamu, Fukahori, Masaru, Sawada, Takeshi, Aoki, Masahiko, Yamamoto, Masaki, Nagao, Miki, Morita, Satoshi, Nakajima, Takako E, Muto, Manabu, Hamazaki, Yoko

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TB-01 HUMAN IPS CELL-DERIVED BRAIN TUMOR MODEL UNCOVERS THE EMBRYONIC STEM CELL SIGNATURE AS A KEY DRIVER IN ATYPICAL TERATOID/RHABDOID TUMOR by Terada, Yukinori, Jo, Norihide, Arakawa, Yoshiki, Mineharu, Yohei, Yamada, Yasuhiro, Miyamoto, Susumu

“…Atypical teratoid/rhabdoid tumor (AT/RT), which harbors SMARCB1 mutation and exhibits a characteristic histology of rhabdoid cells, has a poor prognosis…”
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A case of post-transplant adult T-cell leukemia/lymphoma presenting myelopathy similar to but distinct from human T-cell leukemia virus type I (HTLV- I)-associated myelopathy by Kawamata, Toyotaka, Ohno, Nobuhiro, Sato, Kota, Kobayashi, Masayuki, Jo, Norihide, Yuji, Koichiro, Tanosaki, Ryuji, Yamano, Yoshihisa, Tojo, Arinobu, Uchimaru, Kaoru

“…Introduction Adult T-cell leukemia/lymphoma (ATL) responds poorly to conventional chemotherapy, but allogeneic stem cell transplantation (allo-SCT) may improve…”
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Single-Unit Cord Blood Transplantation after Granulocyte Colony-Stimulating Factor–Combined Myeloablative Conditioning for Myeloid Malignancies Not in Remission by Konuma, Takaaki, Kato, Seiko, Ooi, Jun, Oiwa-Monna, Maki, Ebihara, Yasuhiro, Mochizuki, Shinji, Yuji, Koichiro, Ohno, Nobuhiro, Kawamata, Toyotaka, Jo, Norihide, Yokoyama, Kazuaki, Uchimaru, Kaoru, Asano, Shigetaka, Tojo, Arinobu, Takahashi, Satoshi

“…Abstract High disease burden in myeloablative allogeneic hematopoietic stem cell transplantation is associated with adverse outcomes in patients with acute…”
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