Search Results - "Jo, Heejoon"

SCISSOR: a framework for identifying structural changes in RNA transcripts by Choi, Hyo Young, Jo, Heejoon, Zhao, Xiaobei, Hoadley, Katherine A., Newman, Scott, Holt, Jeremiah, Hayward, Michele C., Love, Michael I., Marron, J. S., Hayes, D. Neil

“…High-throughput sequencing protocols such as RNA-seq have made it possible to interrogate the sequence, structure and abundance of RNA transcripts at higher…”
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Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell by Puray-Chavez, Maritza, LaPak, Kyle M., Schrank, Travis P., Elliott, Jennifer L., Bhatt, Dhaval P., Agajanian, Megan J., Jasuja, Ria, Lawson, Dana Q., Davis, Keanu, Rothlauf, Paul W., Liu, Zhuoming, Jo, Heejoon, Lee, Nakyung, Tenneti, Kasyap, Eschbach, Jenna E., Shema Mugisha, Christian, Cousins, Emily M., Cloer, Erica W., Vuong, Hung R., VanBlargan, Laura A., Bailey, Adam L., Gilchuk, Pavlo, Crowe, James E., Diamond, Michael S., Hayes, D. Neil, Whelan, Sean P.J., Horani, Amjad, Brody, Steven L., Goldfarb, Dennis, Major, M. Ben, Kutluay, Sebla B.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) variants govern transmissibility, responsiveness to vaccination, and disease severity…”
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LCCC 1025: a phase II study of everolimus, trastuzumab, and vinorelbine to treat progressive HER2-positive breast cancer brain metastases by Van Swearingen, Amanda E. D., Siegel, Marni B., Deal, Allison M., Sambade, Maria J., Hoyle, Alan, Hayes, D. Neil, Jo, Heejoon, Little, Paul, Dees, Elizabeth Claire, Muss, Hyman, Jolly, Trevor, Zagar, Timothy M., Patel, Nirali, Miller, C. Ryan, Parker, Joel S., Smith, J. Keith, Fisher, Julie, Shah, Nikita, Nabell, Lisle, Nanda, Rita, Dillon, Patrick, Abramson, Vandana, Carey, Lisa A., Anders, Carey K.

“…Purpose HER2 + breast cancer (BC) is an aggressive subtype with high rates of brain metastases (BCBM). Two-thirds of HER2 + BCBM demonstrate activation of the…”
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Analgesic Effect of Human Placenta Hydrolysate on CFA-Induced Inflammatory Pain in Mice by Park, Keun-Tae, Jo, Heejoon, Jeon, So-Hyun, Jeong, Kyeongsoo, Im, Minju, Kim, Jae-Won, Jung, Jong-Pil, Jung, Hoe Chang, Lee, Jae Hun, Kim, Woojin

“…To evaluate the efficacy of human placenta hydrolysate (HPH) in a mice model of CFA-induced inflammatory pain. TNF-α, IL-1β, and IL-6 are key pro-inflammatory…”
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The effect of ginger extract on cisplatin-induced acute anorexia in rats by Kim, Hyeonah, Park, Keun-Tae, Jo, Heejoon, Shin, Yuchan, Chung, Geehoon, Ko, Seong-Gyu, Jin, Young-Ho, Kim, Woojin

“…Cisplatin is a platinum-based chemotherapeutic agent widely used to treat various cancers. However, several side effects have been reported in treated…”
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Red Ginger Extract Prevents the Development of Oxaliplatin-Induced Neuropathic Pain by Inhibiting the Spinal Noradrenergic System in Mice by Park, Keun-Tae, Jo, Heejoon, Kim, Bonglee, Kim, Woojin

“…Oxaliplatin is a well-known chemotherapeutic drug that is widely used to treat colorectal cancer. However, it can induce acute side effects in up to 90% of…”
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Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery by Sipe, Laura M, Chaib, Mehdi, Korba, Emily B, Jo, Heejoon, Lovely, Mary Camille, Counts, Brittany R, Tanveer, Ubaid, Holt, Jeremiah R, Clements, Jared C, John, Neena A, Daria, Deidre, Marion, Tony N, Bohm, Margaret S, Sekhri, Radhika, Pingili, Ajeeth K, Teng, Bin, Carson, James A, Hayes, D Neil, Davis, Matthew J, Cook, Katherine L, Pierre, Joseph F, Makowski, Liza

“…Bariatric surgery is a sustainable weight loss approach, including vertical sleeve gastrectomy (VSG). Obesity exacerbates tumor growth, while diet-induced…”
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Combined Targeted DNA Sequencing in Non-Small Cell Lung Cancer (NSCLC) Using UNCseq and NGScopy, and RNA Sequencing Using UNCqeR for the Detection of Genetic Aberrations in NSCLC by Zhao, Xiaobei, Wang, Anyou, Walter, Vonn, Patel, Nirali M, Eberhard, David A, Hayward, Michele C, Salazar, Ashley H, Jo, Heejoon, Soloway, Matthew G, Wilkerson, Matthew D, Parker, Joel S, Yin, Xiaoying, Zhang, Guosheng, Siegel, Marni B, Rosson, Gary B, Earp, 3rd, H Shelton, Sharpless, Norman E, Gulley, Margaret L, Weck, Karen E, Hayes, D Neil, Moschos, Stergios J

“…The recent FDA approval of the MiSeqDx platform provides a unique opportunity to develop targeted next generation sequencing (NGS) panels for human disease,…”
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Correlation of alterations in the KEAP1/CUL3/NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma by Sheth, Siddharth, Farquhar, Douglas R., Schrank, Travis P., Stepp, Wesley, Mazul, Angela, Hayward, Michele, Lenze, Nicholas, Little, Paul, Jo, Heejoon, Major, M. Ben, Chera, Bhishamjit S., Zevallos, Jose P., Hayes, D. Neil

“…Objectives Patients with laryngeal squamous cell carcinoma (LSCC) often fail radiation therapy (RT), when received as monotherapy or in combination with other…”
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Prognostic implications of stromal hyaluronic acid protein expression in resected oropharyngeal and oral cavity cancers by Sun, Der Sheng, Won, Hye Sung, Hong, Soon Auck, Hong, Ji Hyung, Jo, Heejoon, Lee, Heejin, Kim, Okran, Lee, Myung Ah, Ko, Yoon Ho

“…Hyaluronic acid (HA) regulates cell adhesion, migration and proliferation in various cancers. The clinical implications of HA in resected head and neck…”
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Genomic profiling of endometrial cancer and relationship with volume of endometrial cancer disease spread by Sullivan, Stephanie A., Hawkins, Gabriel, Zhao, Xiobai, Jo, Heejoon, Hayes, Neil, Deng, Xiaoyan, Bandyopadhyay, Dipankar, Bae-Jump, Victoria L., Rossi, Emma C.

“…•TP53 mutations are common in serous endometrial tumors.•Endometrial tumors with micro and macrometastasis are more likely than tumors with ITC only to have…”
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Prognostic implication of ERCC1 protein expression in resected oropharynx and oral cavity cancer by An, Ho Jung, Jo, Heejoon, Jung, Chan Kwon, Kang, Jin Hyoung, Kim, Min Sik, Sun, Dong-Il, Cho, Kwang Jae, Cho, Jung-Hae, Won, Hye Sung, Sun, Der Sheng, Ko, Yoon Ho

“…Excision repair cross complement group 1 (ERCC1) expression is a predictive biomarker for platinum-containing treatment in squamous cell carcinoma of head and…”
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Abstract 5448: Integrative analysis of microRNA expression identifies two biologically distinct and clinically relevant subtypes of head and neck squamous cell carcinoma by Holt, Jeremiah R., Jo, Heejoon, Walter, Vonn, Zhao, Xiaobei, Hayes, David Neil, Ko, Yoon Ho

“…Abstract Purpose: The objective of this study is to investigate the potential role of microRNAs (miRNA) as molecular markers of tumor heterogeneity in head and…”
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Integrative Analysis of miRNAs Identifies Clinically Relevant Epithelial and Stromal Subtypes of Head and Neck Squamous Cell Carcinoma by Holt, Jeremiah, Walter, Vonn, Yin, Xiaoying, Marron, David, Wilkerson, Matthew D, Choi, Hyo Young, Zhao, Xiaobei, Jo, Heejoon, Hayes, David Neil, Ko, Yoon Ho

“…The objective of this study is to characterize the role of miRNAs in the classification of head and neck squamous cell carcinoma (HNSCC). Here, we analyzed 562…”
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Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer by Pingili, Ajeeth K., Chaib, Mehdi, Sipe, Laura M., Miller, Emily J., Teng, Bin, Sharma, Rahul, Yarbro, Johnathan R., Asemota, Sarah, Al Abdallah, Qusai, Mims, Tahliyah S., Marion, Tony N., Daria, Deidre, Sekhri, Radhika, Hamilton, Alina M., Troester, Melissa A., Jo, Heejoon, Choi, Hyo Young, Hayes, D. Neil, Cook, Katherine L., Narayanan, Ramesh, Pierre, Joseph F., Makowski, Liza

“…Immune checkpoint blockade (ICB) has improved outcomes in some cancers. A major limitation of ICB is that most patients fail to respond, which is partly…”
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Integrative analysis of microRNAs identifies clinically relevant epithelial and stromal subtypes of head and neck squamous cell carcinoma by Holt, Jeremiah, Walter, Vonn, Yin, Xiaoying, Marron, David, Wilkerson, Matthew D., Choi, Hyo Young, Zhao, Xiaobei, Jo, Heejoon, Hayes, David Neil, Ko, Yoon Ho

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Abstract PR01: HPV structure and functional alterations impact prognosis in HPV (+) oropharyngeal squamous cell carcinoma by Zevallos, Jose P., Mazul, Angela L., Zhao, Xiaobei, Jo, Heejoon, Nathan, Cherie-Ann, Olshan, Andrew F., Chera, Bhishamjit S., Hayes, D. Neil

“…Abstract Background: Over the last two decades, there has been a sharp increase in the incidence of oropharyngeal squamous cell carcinoma (OPSCC) linked to…”
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Abstract PS17-04: Immune checkpoint blockade reprograms tumor microenvironment and systemic immune landscape in obesity associated triple negative breast cancer by Pingili, Ajeeth K, Chaib, Mehdi, Sipe, Laura M, Miller, Emily J, Teng, Bin, Sharma, Rahul, Abdallah, Qusai AI, Daria, Deidra, Sekhri, Radhika, Jo, Heejoon, Tahliyah, Mims S, Hayes, D. Neil, Pierre, Joseph F, Makowski, Liza

“…Abstract Few targeted therapies exist for triple negative breast cancer (TNBC), an aggressive and deadly subtype. Obesity exacerbates poor outcomes in TNBC due…”
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Abstract 2091: DeepBTS: Prediction of recurrence-free survival of non-small cell lung cancer using time-binned deep neural network by An, Ho Jung, Lee, Bora, Chun, Sang Hoon, Hong, Ji Hyung, Woo, In Sook, Kim, Seoree, Jeong, Joon Won, Kim, Jae Jun, Lee, Hyun Woo, Park, Sungsoo, Jo, Heejoon, Ko, Yoon Ho

“…Abstract Introduction: Accurate prediction of non-small cell lung cancer (NSCLC) prognosis after surgery is still challenging. Cox proportional hazard model is…”
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Improved Tumor Purity Metrics in Next-generation Sequencing for Clinical Practice: The Integrated Interpretation of Neoplastic Cellularity and Sequencing Results (IINCaSe) Approach by Patel, Nirali M, Jo, Heejoon, Eberhard, David A, Yin, Xiaoying, Hayward, Michele C, Stein, Matthew K, Hayes, David Neil, Grilley-Olson, Juneko E

“…Neoplastic cellularity contributes to the analytic sensitivity of most present technologies for mutation detection, such that they underperform when stroma and…”
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