Search Results - "Jo, Ha‐Neul"
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A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy
Published in EMBO molecular medicine (07-07-2021)“…The FZD4:LRP5:TSPAN12 receptor complex is activated by the secreted protein Norrin in retinal endothelial cells and leads to βcatenin‐dependent formation of…”
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A tug of war between DCC and ROBO1 signaling during commissural axon guidance
Published in Cell reports (Cambridge) (30-05-2023)“…Dynamic and coordinated axonal responses to changing environments are critical for establishing neural connections. As commissural axons migrate across the CNS…”
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A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis
Published in Scientific reports (31-05-2017)“…Activation of the endothelium by pro-inflammatory stimuli plays a key role in the pathogenesis of a multitude of vascular diseases. Angiogenesis is a crucial…”
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Endothelial periostin regulates vascular remodeling by promoting endothelial dysfunction in pulmonary arterial hypertension
Published in Animal cells and systems (2024)“…Pulmonary arterial hypertension (PAH) is characterized by vascular remodeling associated with extracellular matrix (ECM) deposition, vascular cell…”
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Endothelial miR-26a regulates VEGF-Nogo-B receptor-mediated angiogenesis
Published in BMB reports (01-07-2017)“…The Nogo-B receptor (NgBR) is necessary for not only Nogo-B-mediated angiogenesis but also vascular endothelial growth factor (VEGF) -induced angiogenesis…”
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Extracts of Phlomoides umbrosa Turczaninow alleviate allergic airway inflammation in lipopolysaccharide-stimulated RAW 264.7 cells and ovalbumin-induced hyper-responsiveness mouse model
Published in Food science and biotechnology (01-08-2024)“…Phlomoides umbrosa Turczaninow (PU), a traditional Korean medicinal herb, exhibits osteogenic and anti-inflammatory effects. This research explored the effect…”
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A Frizzled4-LRP5 agonist promotes blood-retina barrier function by inducing a Norrin-like transcriptional response
Published in iScience (18-08-2023)“…Norrin (NDP) and WNT7A/B induce and maintain the blood-brain and blood-retina barrier (BBB, BRB) by stimulating the Frizzled4-LDL receptor related protein 5/6…”
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Negative regulation of NOD1 mediated angiogenesis by PPARγ-regulated miR-125a
Published in Biochemical and biophysical research communications (01-01-2017)“…Infection with pathogens activates the endothelial cell and its sustained activation may result in impaired endothelial function. Endothelial dysfunction…”
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Ref-1 redox activity modulates canonical Wnt signaling in endothelial cells
Published in Free radical biology & medicine (01-11-2024)Get full text
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