Search Results - "Jiumao Lin"
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Anticancer Properties of Traditional Chinese Medicine
Published in Combinatorial chemistry & high throughput screening (01-01-2017)“…Cancer is a systemic disease. Cancer occurrence is associated with several factors, including cell proliferation, apoptosis, metastasis, tumor microenvironment…”
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Babao Dan inhibits lymphangiogenesis of gastric cancer in vitro and in vivo via lncRNA-ANRIL/VEGF-C/VEGFR-3 signaling axis
Published in Biomedicine & pharmacotherapy (01-10-2022)“…Gastric cancer (GC) is one of the most common gastrointestinal malignancies in the world. Growing evidence emphasizes the critical role of long non-coding RNA…”
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Qingjie Fuzheng Granule attenuates 5-fluorouracil-induced intestinal mucosal damage
Published in Biomedicine & pharmacotherapy (01-10-2019)“…5-Fluorouracil (5-FU)-based chemotherapy often causes several drawbacks including weight loss, diarrhea, myelosuppression, and the intestinal mucositis. This…”
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Qingjie Fuzheng Granule suppresses lymphangiogenesis in colorectal cancer via the VEGF-C/VEGFR-3 dependent PI3K/AKT pathway
Published in Biomedicine & pharmacotherapy (01-05-2021)“…To investigate the effect of Qingjie Fuzheng Granule (QFG) on lymphangiogenesis and lymphatic metastasis in colorectal cancer. The effects of QFG on the…”
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Babao Dan induces gastric cancer cell apoptosis via regulating MAPK and NF-κB signaling pathways
Published in Journal of international medical research (01-10-2019)“…Objective The objective was to further investigate apoptosis induction by Babao Dan (BBD), which supports its anti-tumor mechanisms, using two human gastric…”
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Chemotherapeutic Drugs Induce Different Gut Microbiota Disorder Pattern and NOD/RIP2/NF-κB Signaling Pathway Activation That Lead to Different Degrees of Intestinal Injury
Published in Microbiology spectrum (21-12-2022)“…5-Fluorouracil (5-FU), irinotecan (CPT-11), oxaliplatin (L-OHP), and calcium folinate (CF) are widely used chemotherapeutic drugs to treat colorectal cancer…”
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Ursolic acid inhibits colorectal cancer angiogenesis through suppression of multiple signaling pathways
Published in International journal of oncology (01-11-2013)“…Angiogenesis plays a critical role in the development of solid tumors by supplying nutrients and oxygen to support continuous growth of tumor as well as…”
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Qualitative and Quantitative Analysis of the Major Constituents in Shexiang Tongxin Dropping Pill by HPLC-Q-TOF-MS/MS and UPLC-QqQ-MS/MS
Published in Molecules (Basel, Switzerland) (14-10-2015)“…Shexiang Tongxin dropping pill (STP) is a traditional Chinese medicine formula that consists of total saponins of ginseng, synthetic Calculus bovis, bear gall,…”
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Scutellaria barbata D. Don inhibits 5-fluorouracil resistance in colorectal cancer by regulating PI3K/AKT pathway
Published in Oncology reports (01-10-2017)“…5-Fluorouracil (5-FU) resistance or multidrug resistance (MDR) has become a major obstacle in clinical treatment of cancers including colorectal cancer (CRC)…”
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Anlotinib Overcomes Multiple Drug Resistant Colorectal Cancer Cells via Inactivating PI3K/AKT Pathway
Published in Anti-cancer agents in medicinal chemistry (2021)“…Anlotinib is a multi-target tyrosine kinase inhibitor that has been reported to have activity against colorectal cancer. However, the mechanisms of how…”
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Babao Dan alleviates gut immune and microbiota disorders while impacting the TLR4/MyD88/NF-кB pathway to attenuate 5-Fluorouracil-induced intestinal injury
Published in Biomedicine & pharmacotherapy (01-10-2023)“…Adjuvant chemotherapy based on 5-fluorouracil (5-FU), such as FOLFOX, is suggested as a treatment for gastrointestinal cancer. Yet, intestinal damage continues…”
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Cell division cycle associated 5 promotes colorectal cancer progression by activating the ERK signaling pathway
Published in Oncogenesis (New York, NY) (26-02-2019)“…Cell division cycle associated 5 (CDCA5) is implicated in the development and progression of a variety of human cancers. Functional significance of CDCA5 in…”
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Pien Tze Huang inhibits metastasis of human colorectal carcinoma cells via modulation of TGF-β1/ZEB/miR-200 signaling network
Published in International journal of oncology (01-02-2015)“…Tumor metastasis, a complex process involving the spread of malignant tumor cells from a primary tumor site to a distant organ, is a major cause of failure of…”
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Jiedu Xiaozheng Yin Inhibits the Progression of Colitis Associated Colorectal Cancer by Stimulating Macrophage Polarization Towards an M1 Phenotype via the TLR4 Pathway
Published in Integrative cancer therapies (01-01-2024)“…To investigate the effect of Jiedu Xiaozheng Yin (JXY) on the polarization of macrophages in colitis-associated colon cancer (CAC). An orthotopic model of CAC…”
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Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial–mesenchymal transition through the TGF-β/Smad pathway
Published in Journal of international medical research (01-06-2020)“…Objective To investigate the anti-metastatic effects of Babao Dan (BBD) on gastric cancer (GC) cells (AGS and MGC80-3) and explore the underlying molecular…”
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Hedyotis diffusa Willd inhibits colorectal cancer growth in vivo via inhibition of STAT3 signaling pathway
Published in International journal of molecular sciences (18-05-2012)“…Signal Transducer and Activator of Transcription 3 (STAT3), a common oncogenic mediator, is constitutively activated in many types of human cancers; therefore…”
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Hedyotis Diffusa Willd extract induces apoptosis via activation of the mitochondrion-dependent pathway in human colon carcinoma cells
Published in International journal of oncology (01-11-2010)“…Hedyotis Diffusa Willd has been used as a major component in several Chinese medicine formulations for the clinical treatment of colorectal cancer. However,…”
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Comparative proteomics—network analysis of proteins responsible for ursolic acid–induced cytotoxicity in colorectal cancer cells
Published in Tumor biology (01-03-2017)“…Ursolic acid is a key active compound present in many medicinal herbs that have been widely used in traditional Chinese medicine for the clinical treatment of…”
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Qianliening Capsule Promotes Mitochondrial Pathway Mediated the Apoptosis of Benign Prostatic Hyperplasia Epithelial-1 Cells by Regulating the miRNA-181a
Published in International journal of gerontology (01-09-2018)“…Our previous studies reported that Qianliening capsule (QC) has a significant therapeutic effect on BPH. Therefore, we investigated the effect QC on apoptosis…”
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