Search Results - "Jinno, Teppei"

CD163+CD204+ tumor-associated macrophages contribute to T cell regulation via interleukin-10 and PD-L1 production in oral squamous cell carcinoma by Kubota, Keigo, Moriyama, Masafumi, Furukawa, Sachiko, Rafiul, Haque A. S. M., Maruse, Yasuyuki, Jinno, Teppei, Tanaka, Akihiko, Ohta, Miho, Ishiguro, Noriko, Yamauchi, Masaaki, Sakamoto, Mizuki, Maehara, Takashi, Hayashida, Jun-Nosuke, Kawano, Shintaro, Kiyoshima, Tamotsu, Nakamura, Seiji

“…Tumor-associated macrophages (TAMs) promote cancer cell proliferation, invasion, and metastasis by producing various mediators. Although preclinical studies…”
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Increased expression of interleukin-6 predicts poor response to chemoradiotherapy and unfavorable prognosis in oral squamous cell carcinoma by JINNO, TEPPEI, KAWANO, SHINTARO, MARUSE, YASUYUKI, MATSUBARA, RYOTA, GOTO, YUICHI, SAKAMOTO, TAIKI, HASHIGUCHI, YUMA, KANEKO, NAOKI, TANAKA, HIDEAKI, KITAMURA, RYOJI, TOYOSHIMA, TAKESHI, JINNO, AKIKO, MORIYAMA, MASAFUMI, OOBU, KAZUNARI, KIYOSHIMA, TAMOTSU, NAKAMURA, SEIJI

“…Recent studies have revealed that cancer cells are exacerbated by chronic inflammation. The present study examined the immunohistochemical expression for…”
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Immunohistochemical location of the p75 neurotrophin receptor (p75NTR) in oral leukoplakia and oral squamous cell carcinoma by Kiyosue, Takahiro, Kawano, Shintaro, Matsubara, Ryota, Goto, Yuichi, Hirano, Mitsuhiro, Jinno, Teppei, Toyoshima, Takeshi, Kitamura, Ryoji, Oobu, Kazunari, Nakamura, Seiji

“…Background Recent studies have demonstrated that the p75 neurotrophin receptor (p75NTR) is a useful marker of keratinocyte stem cells. Although the stem cell…”
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Clinical Significance of Combined Assessment of the Maximum Standardized Uptake Value of F-18 FDG PET with Nodal Size in the Diagnosis of Cervical Lymph Node Metastasis of Oral Squamous Cell Carcinoma by Matsubara, Ryota, DDS, PhD, Kawano, Shintaro, DDS, PhD, Chikui, Toru, DDS, PhD, Kiyosue, Takahiro, DDS, PhD, Goto, Yuichi, DDS, PhD, Hirano, Mitsuhiro, DDS, Jinno, Teppei, DDS, Nagata, Tetsuji, DDS, PhD, Oobu, Kazunari, DDS, PhD, Abe, Koichiro, MD, PhD, Nakamura, Seiji, DDS, PhD

“…Rationale and Objectives This study aimed to elucidate the diagnostic accuracy of F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed…”
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Tongue squamous cell carcinoma producing both parathyroid hormone-related protein and granulocyte colony-stimulating factor: a case report and literature review by Kaneko, Naoki, Kawano, Shintaro, Matsubara, Ryota, Goto, Yuichi, Jinno, Teppei, Maruse, Yasuyuki, Sakamoto, Taiki, Hashiguchi, Yuma, Iida, Masakazu, Nakamura, Seiji

“…Paraneoplastic syndrome generally results from tumor-derived hormones or peptides that cause metabolic derangements. Common metabolic conditions include…”
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Erratum to: Tongue squamous cell carcinoma producing both parathyroid hormone-related protein and granulocyte colony-stimulating factor: a case report and literature review by Kaneko, Naoki, Kawano, Shintaro, Matsubara, Ryota, Goto, Yuichi, Jinno, Teppei, Maruse, Yasuyuki, Sakamoto, Taiki, Hashiguchi, Yuma, Iida, Masakazu, Nakamura, Seiji

“…Declarations Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License…”
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Tumor‐suppressive roles of ΔNp63β‐miR‐205 axis in epithelial–mesenchymal transition of oral squamous cell carcinoma via targeting ZEB1 and ZEB2 by Hashiguchi, Yuma, Kawano, Shintaro, Goto, Yuichi, Yasuda, Kaori, Kaneko, Naoki, Sakamoto, Taiki, Matsubara, Ryota, Jinno, Teppei, Maruse, Yasuyuki, Tanaka, Hideaki, Morioka, Masahiko, Hattori, Taichi, Tanaka, Shoichi, Kiyoshima, Tamotsu, Nakamura, Seiji

“…We previously revealed that epithelial‐to‐mesenchymal transition (EMT) was mediated by ΔNp63β, a splicing variant of ΔNp63, in oral squamous cell carcinoma…”
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Critical roles of Wnt5a–Ror2 signaling in aggressiveness of tongue squamous cell carcinoma and production of matrix metalloproteinase-2 via ΔNp63β-mediated epithelial–mesenchymal transition by Sakamoto, Taiki, Kawano, Shintaro, Matsubara, Ryota, Goto, Yuichi, Jinno, Teppei, Maruse, Yasuyuki, Kaneko, Naoki, Hashiguchi, Yuma, Hattori, Taichi, Tanaka, Shoichi, Kitamura, Ryoji, Kiyoshima, Tamotsu, Nakamura, Seiji

“…Highlights • ΔNp63β negatively regulates Wnt5a, Ror2 and MMP-2 expression in tongue SCC cell lines. • Wnt5a–Ror2 signaling affects tongue SCC cell motility and…”
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Differential roles of kallikrein-related peptidase 6 in malignant transformation and ΔNp63β-mediated epithelial-mesenchymal transition of oral squamous cell carcinoma by Kaneko, Naoki, Kawano, Shintaro, Yasuda, Kaori, Hashiguchi, Yuma, Sakamoto, Taiki, Matsubara, Ryota, Goto, Yuichi, Jinno, Teppei, Maruse, Yasuyuki, Morioka, Masahiko, Hattori, Taichi, Tanaka, Shoichi, Tanaka, Hideaki, Kiyoshima, Tamotsu, Nakamura, Seiji

“…•ΔNp63β positively regulates KLK6 and PAR2, and negatively regulates PAR1 in OSCC.•Up-regulates KLK6-PAR2 and down-regulates PAR1 induces malignant…”
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Increased ΔNp63 expression is predictive of malignant transformation in oral epithelial dysplasia and poor prognosis in oral squamous cell carcinoma by MATSUBARA, Ryota, KAWANO, Shintaro, KIYOSUE, Takahiro, GOTO, Yuichi, HIRANO, Mitsuhiro, JINNO, Teppei, TOYOSHIMA, Takeshi, KITAMURA, Ryoji, OOBU, Kazunari, NAKAMURA, Seiji

“…This study examined immunohistochemical expression of ΔNp63, a keratinocyte stem cell marker, in oral leukoplakia (OL) and oral squamous cell carcinoma (OSCC)…”
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Possible involvement of ΔNp63 downregulation in the invasion and metastasis of oral squamous cell carcinoma via induction of a mesenchymal phenotype by Goto, Yuichi, Kawano, Shintaro, Matsubara, Ryota, Kiyosue, Takahiro, Hirano, Mitsuhiro, Jinno, Teppei, Maruse, Yasuyuki, Toyoshima, Takeshi, Kitamura, Ryoji, Tanaka, Hideaki, Oobu, Kazunari, Nakamura, Seiji

“…Epithelial-to-mesenchymal transition (EMT), an essential developmental program, is involved in tumor progression. ΔNp63, a homolog of p53, is associated with…”
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Possible involvement of [Delta]Np63 downregulation in the invasion and metastasis of oral squamous cell carcinoma via induction of a mesenchymal phenotype by Goto, Yuichi, Kawano, Shintaro, Matsubara, Ryota, Kiyosue, Takahiro, Hirano, Mitsuhiro, Jinno, Teppei, Maruse, Yasuyuki, Toyoshima, Takeshi, Kitamura, Ryoji, Tanaka, Hideaki, Oobu, Kazunari, Nakamura, Seiji

“…Epithelial-to-mesenchymal transition (EMT), an essential developmental program, is involved in tumor progression. [Delta]Np63, a homolog of p53, is associated…”
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Clinicopathological evaluation of pre-operative chemoradiotherapy with S-1 as a treatment for locally advanced oral squamous cell carcinoma by KAWANO, SHINTARO, ZHENG, YANQUN, OOBU, KAZUNARI, MATSUBARA, RYOTA, GOTO, YUICHI, CHIKUI, TORU, YOSHITAKE, TADAMASA, KIYOSHIMA, TAMOTSU, JINNO, TEPPEI, MARUSE, YASUYUKI, MITATE, EIJI, KITAMURA, RYOJI, TANAKA, HIDEAKI, TOYOSHIMA, TAKESHI, SUGIURA, TSUYOSHI, NAKAMURA, SEIJI

“…The administration of pre-operative chemotherapy with S-1 and concurrent radiotherapy at a total dose of 30 Gy was clinicopathologically evaluated as a…”
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Cytokeratin 17 mRNA as a prognostic marker of oral squamous cell carcinoma by Kitamura, Ryoji, Toyoshima, Takeshi, Tanaka, Hideaki, Kawano, Shintaro, Matsubara, Ryota, Goto, Yuichi, Jinno, Teppei, Maruse, Yasuyuki, Oobu, Kazunari, Nakamura, Seiji

“…Despite diagnostic and therapeutic advances, the 5-year survival rate of oral squamous cell carcinoma (OSCC) remains between 70-80% due to recurrences and…”
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