Search Results - "Jinno, Shozo"

Topographic differences in adult neurogenesis in the mouse hippocampus: A stereology-based study using endogenous markers by Jinno, Shozo

“…The hippocampus plays a critical role in various cognitive and affective functions. Increasing evidence shows that these functions are topographically…”
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Decline in adult neurogenesis during aging follows a topographic pattern in the mouse hippocampus by Jinno, Shozo

“…In the rodent brain, diverse functions are topographically distributed within the hippocampus. For instance, the dorsal (septal) hippocampus is involved in…”
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Potential link between antidepressant-like effects of ketamine and promotion of adult neurogenesis in the ventral hippocampus of mice by Yamada, Jun, Jinno, Shozo

“…Recent studies have shown that ketamine, an open channel blocker of the N-methyl-d-aspartate receptor (NMDAR), is effective for patients with…”
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Aging affects new cell production in the adult hippocampus: A quantitative anatomic review by Jinno, Shozo

“…•Diminution in neural plasticity may underlie age-related brain dysfunction.•Hippocampus is differentiated along its dorsoventral and transverse…”
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Molecular heterogeneity of aggrecan‐based perineuronal nets around five subclasses of parvalbumin‐expressing neurons in the mouse hippocampus by Yamada, Jun, Jinno, Shozo

“…ABSTRACT Subsets of GABAergic neurons are surrounded by perineuronal nets (PNNs), which play a critical role in the regulation of neural plasticity and…”
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Signal Transducer and Activator of Transcription 3 Activation in Hippocampal Neural Stem Cells and Cognitive Deficits in Mice Following Short-term Cuprizone Exposure by Ohgomori, Tomohiro, Jinno, Shozo

“…•Cognitive deficits were induced following short-term CPZ exposure in mice.•NPCs/NGCs but not NSCs in the hippocampus were decreased by CPZ exposure.•STAT3 was…”
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Modulation of neuropathology and cognitive deficits by lipopolysaccharide preconditioning in a mouse pilocarpine model of status epilepticus by Ohgomori, Tomohiro, Jinno, Shozo

“…Recent studies indicate that microglia may play a critical role in epileptogenesis during the early post-status epilepticus (SE) period. In this study, we…”
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Cuprizone-induced demyelination in the mouse hippocampus is alleviated by phytoestrogen genistein by Ohgomori, Tomohiro, Jinno, Shozo

“…One of the major female sex hormones, estrogen, can influence a variety of mental states. Individuals with multiple sclerosis (MS) often suffer from mental…”
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The expression of keratan sulfate reveals a unique subset of microglia in the mouse hippocampus after pilocarpine‐induced status epileptics by Ohgomori, Tomohiro, Jinno, Shozo

“…Induction of keratan sulfate in microglia has been found in several animal models of neurological disorders. However, the significance of keratan…”
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Novel objective classification of reactive microglia following hypoglossal axotomy using hierarchical cluster analysis by Yamada, Jun, Jinno, Shozo

“…A total of 136 microglia were intracellularly labeled and their morphological features were evaluated by 3D morphometric measurement. According to hierarchical…”
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Increased Synthesis of Chondroitin Sulfate Proteoglycan Promotes Adult Hippocampal Neurogenesis in Response to Enriched Environment by Yamada, Jun, Nadanaka, Satomi, Kitagawa, Hiroshi, Takeuchi, Kosei, Jinno, Shozo

“…Chondroitin sulfate proteoglycan (CSPG) is a candidate regulator of embryonic neurogenesis. The aim of this study was to specify the functional significance of…”
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Structural organization of long-range GABAergic projection system of the hippocampus by Jinno, Shozo

“…GABA is a key mediator of neural activity in the mammalian central nervous system, and a diverse set of GABAergic neurons utilize GABA as a transmitter. It has…”
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PSA-NCAM Colocalized with Cholecystokinin-Expressing Cells in the Hippocampus Is Involved in Mediating Antidepressant Efficacy by Yamada, Jun, Sato, Chihiro, Konno, Kohtarou, Watanabe, Masahiko, Jinno, Shozo

“…The extracellular glycan polysialic acid linked to neural cell adhesion molecule (PSA-NCAM) is principally expressed in the developing brain and the adult…”
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Subclass-specific formation of perineuronal nets around parvalbumin-expressing GABAergic neurons in Ammon's horn of the mouse hippocampus by Yamada, Jun, Jinno, Shozo

“…ABSTRACT Perineuronal nets (PNNs) are closely associated with parvalbumin‐positive (PV+) neurons, and play a major role in controlling developmental neural…”
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Stereological estimation of numerical densities of glutamatergic principal neurons in the mouse hippocampus by Jinno, Shozo, Kosaka, Toshio

“…Recent studies have emphasized functional dissociations between dorsal and ventral hippocampus in learning, emotion, and affect. A rigorous quantitative…”
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Cell type- and region-specific enhancement of adult hippocampal neurogenesis by daidzein in middle-aged female mice by Yamada, Jun, Hatabe, Jun, Tankyo, Kaori, Jinno, Shozo

“…Adult hippocampal neurogenesis is associated with various brain functions, such as learning, memory, and emotion. Intriguingly, reduction in new cell…”
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Late postnatal shifts of parvalbumin and nitric oxide synthase expression within the GABAergic and glutamatergic phenotypes of inferior colliculus neurons by Fujimoto, Hisataka, Konno, Kotaro, Watanabe, Masahiko, Jinno, Shozo

“…ABSTRACT The inferior colliculus (IC) is partitioned into three subdivisions: the dorsal and lateral cortices (DC and LC) and the central nucleus (ICC), and…”
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S100A6 (calcyclin) is a novel marker of neural stem cells and astrocyte precursors in the subgranular zone of the adult mouse hippocampus by Yamada, Jun, Jinno, Shozo

“…ABSTRACT S100A6 (calcyclin), an EF‐hand calcium binding protein, is considered to play various roles in the brain, for example, cell proliferation and…”
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Chondroitin sulfate proteoglycan is a potential target of memantine to improve cognitive function via the promotion of adult neurogenesis by Maeda, Shoichiro, Yamada, Jun, Iinuma, Kyoko M., Nadanaka, Satomi, Kitagawa, Hiroshi, Jinno, Shozo

“…Background and Purpose Chondroitin sulfate proteoglycan (CSPG) constitutes the neurogenic niche in the hippocampus. The reduction of hippocampal neurogenesis…”
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Cellular architecture of the mouse hippocampus: A quantitative aspect of chemically defined GABAergic neurons with stereology by Jinno, Shozo, Kosaka, Toshio

“…The structural organization of the central nervous system is an infrastructure of the modern neuroscience. Especially, anatomical research at the cellular…”
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