Search Results - "Jing, Pengyu"
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Activation of the Aryl Hydrocarbon Receptor Leads to Resistance to EGFR TKIs in Non-Small Cell Lung Cancer by Activating Src-mediated Bypass Signaling
Published in Clinical cancer research (01-03-2018)“…The aryl hydrocarbon receptor (AhR) has been generally recognized as a ligand-activated transcriptional factor that responds to xenobiotic chemicals. Recent…”
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Targeting FBW7 as a Strategy to Overcome Resistance to Targeted Therapy in Non-Small Cell Lung Cancer
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Inhibition of EGFR and anaplastic lymphoma kinase (ALK) signaling is highly effective in a subgroup of non-small cell lung cancer (NSCLC) patients with…”
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A high resolution detection approach combining probe drilling and horizontal cross-hole resistivity tomography to interpret water conducting channels ahead of the tunnel: A case study in Yunnan, China
Published in Engineering geology (01-03-2024)“…The geological conditions in Yunnan Province, China, are intricate, and numerous challenges are anticipated during tunnel excavation. The goal of this study…”
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FBW7 loss promotes epithelial-to-mesenchymal transition in non-small cell lung cancer through the stabilization of Snail protein
Published in Cancer letters (10-04-2018)“…The E3 ubiquitin ligase F-box and WD repeat domain containing 7 (FBW7α) functions as a putative tumor suppressor in non-small cell lung cancer (NSCLC) due to…”
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The human microbiome: A promising target for lung cancer treatment
Published in Frontiers in immunology (30-01-2023)“…Lung cancer is the leading cause of cancer-related deaths worldwide, and insights into its underlying mechanisms as well as potential therapeutic strategies…”
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Application of the patient-reported outcome-based postoperative symptom management model in lung cancer: a multicenter randomized controlled trial protocol
Published in Current controlled trials in cardiovascular medicine (17-02-2024)“…Lung cancer is the most common cancer in China, with the highest mortality rate. Surgery is the primary treatment for early lung cancer. However, patients with…”
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miR-24-3p/KLF8 Signaling Axis Contributes to LUAD Metastasis by Regulating EMT
Published in Journal of immunology research (2020)“…Reprogramming of the tumor immune microenvironment is a salient feature during metastasis in LUAD. miR-24-3p and KLF8, which are key regulators of the tumor…”
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Evaluation of an ex vivo fibrogenesis model using human lung slices prepared from small tissues
Published in European journal of medical research (30-03-2023)“…In recent years, there have been breakthroughs in the preclinical research of respiratory diseases, such as organoids and organ tissue chip models, but they…”
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miR-24-3p/FGFR3 Signaling as a Novel Axis Is Involved in Epithelial-Mesenchymal Transition and Regulates Lung Adenocarcinoma Progression
Published in Journal of immunology research (01-01-2018)“…Our previous studies showed that Fibroblast growth factor receptor 3 (FGFR3) contributed to cell growth in lung cancer. However, the correlation between FGFR3…”
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Design and Testing of a Pleurotus pulmonarius Stick Cutting Machine
Published in Agriculture (Basel) (01-10-2024)“…Based on the cultivation environment and material parameters of Pleurotus pulmonarius sticks, a P. pulmonarius stick cutting machine is designed to solve the…”
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Parameter Optimization and Test for the Pulse-Type Gas Explosion Subsoiler
Published in Agriculture (Basel) (01-08-2024)“…To address the problem of large tractive resistance in traditional subsoiling methods, this paper designed a pulse-type gas explosion subsoiler, as well as an…”
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Protein arginine methyltransferase 5 promotes lung cancer metastasis via the epigenetic regulation of miR-99 family/FGFR3 signaling
Published in Cancer letters (28-07-2018)“…Protein arginine methyltransferase 5 (PRMT5) functions as a tumor initiator to regulate several cancer progressions, such as proliferation and apoptosis, by…”
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Comprehensive identification and assessment of clastic rock and water-bearing breccia for water and mud inrush in tunnel: A case study
Published in Tunnelling and underground space technology (01-01-2025)“…Clastic rock and breccia are mostly developed in fault fracture zones. Due to their poor stability and easy occurrence of water structures, tunnels are prone…”
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The PRMT5 inhibitor C9 mitigates hypoxia-induced carboplatin resistance in lung cancer by inducing autophagy
Published in Cell biology international (01-10-2023)“…Hypoxia, a common feature of solid tumors, can promote chemoresistance in cancer cells. PRMT5 mediates various cellular processes involved in cancer…”
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The debatable role of immune checkpoint blockade therapy in lung adenocarcinoma-oriented liver metastatic malignant lesions
Published in Journal of cancer research and clinical oncology (01-08-2023)“…Background The use of anti-PD-1 or PD-L1 inhibitors in combination with other anti-cancer agents was a priority for treating advanced non-small cell lung…”
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An Intermittent Fertilization Control System for Fruit Tree Crown Detection
Published in Agriculture (Basel) (23-10-2024)“…In light of the current dearth of strip intermittent fertilization devices in standardized orchards, this study presents the design of an intermittent…”
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Comprehensive analysis of exosome gene LYPD3 and prognosis/immune cell infiltration in lung cancer
Published in Translational cancer research (31-03-2024)“…Lung cancer (LC) is a leading cause of cancer-associated mortality worldwide, with high incidence and mortality rates. Ly6/PLAUR domain containing 3 (LYPD3) is…”
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The methylation induced by protein arginine methyltransferase 5 promotes tumorigenesis and progression of lung cancer
Published in Journal of thoracic disease (01-12-2018)“…Arginine methylation as a common pattern of post-translational modification is involved in many cellular biological processes. Protein arginine…”
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Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization
Published in Cell death & disease (14-02-2018)“…The liver is the predominant metastatic site for several types of malignancies. Tumor-associated macrophages (TAMs) in the liver play crucial roles in the…”
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ALK and ROS1 as targeted therapy paradigms and clinical implications to overcome crizotinib resistance
Published in Oncotarget (15-03-2016)“…During the past decade, more than 10 targetable oncogenic driver genes have been validated in non-small cell lung cancer (NSCLC). Anaplastic lymphoma kinase…”
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