Search Results - "Jing, Manyi"
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Network pharmacology prediction and molecular docking-based strategy to explore the potential mechanism of Huanglian Jiedu Decoction against sepsis
Published in Computers in biology and medicine (01-05-2022)“…Huanglian Jiedu Decoction (HLJDD) is a classical herbal formula with potential efficacy in the treatment of sepsis. However, the main components and potential…”
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2
The contribution of small heterodimer partner to the occurrence and progression of cholestatic liver injury
Published in Journal of gastroenterology and hepatology (01-06-2024)“…Background and Aim Small heterodimer partner (SHP, encoded by NR0B2) plays an important role in maintaining bile acid homeostasis. The loss of the hepatic…”
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3
Jatrorrhizine Alleviates DSS-Induced Ulcerative Colitis by Regulating the Intestinal Barrier Function and Inhibiting TLR4/MyD88/NF-κB Signaling Pathway
Published in Evidence-based complementary and alternative medicine (19-09-2022)“…Background. Ulcerative colitis (UC), a kind of autoimmune disease with unknown etiology, has been troubling human physical and mental health. Jatrorrhizine…”
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Efficacy and safety of Tanreqing injection combined with antibiotics against Streptococcus pneumoniae pneumonia: A systematic review and meta‐analysis
Published in Journal of clinical pharmacy and therapeutics (01-08-2022)“…What is known and objective Tanreqing injection (TRQ) is a traditional Chinese medicine injection. The goal of this study was to assess the clinical efficacy…”
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Clinical Efficacy and Safety of Qishen Yiqi Dropping Pill Combined with Conventional Western Medicine in the Treatment of Chronic Heart Failure: A Systematic Review and Meta-Analysis
Published in Evidence-based complementary and alternative medicine (2021)“…Objective. The systematic review was designed to evaluate the safety and efficacy of Qishen Yiqi dropping pill combined with conventional Western medicine in…”
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Clinical efficacy and safety of Tanreqing injection combined with antibiotics versus antibiotics alone in the treatment of pulmonary infection patients after chemotherapy with lung cancer: A systematic review and meta‐analysis
Published in Phytotherapy research (01-01-2021)“…This study aimed to evaluate the efficacy and safety of Tanreqing injection (TRQi) in the treatment of pulmonary infection after chemotherapy in patients with…”
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Based on Network Pharmacology to Explore the Potential Bioactive Compounds and Mechanisms of Zuojin Pill for the Treatment of Ulcerative Colitis
Published in Evidence-based complementary and alternative medicine (2021)“…Background. Zuojin Pill (ZJP), a classic prescription, has the potential to prevent ulcerative colitis (UC). However, the active components and mechanisms of…”
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Berberine Attenuates Chronic Atrophic Gastritis Induced by MNNG and Its Potential Mechanism
Published in Frontiers in pharmacology (25-03-2021)“…The purpose of this study was to investigate the therapeutic effect of berberine (BBR) on MNNG-induced chronic atrophic gastritis (CAG) and the possible…”
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9
Paeoniflorin Protects against ANIT-Induced Cholestatic Liver Injury in Rats via the Activation of SIRT1-FXR Signaling Pathway
Published in Evidence-based complementary and alternative medicine (02-09-2021)“…Paeoniflorin (PF), a water-soluble monoterpene glycoside, is initially isolated from the dried roots of Paeonia lactiflora Pall., which has effects on…”
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Mechanism of rutaecarpine on ethanol-induced acute gastric ulcer using integrated metabolomics and network pharmacology
Published in Biomedicine & pharmacotherapy (01-06-2021)“…This study was aimed to explore the mechanism of rutaecarpine (RUT) on ethanol-induced gastric ulcer (GU) in mice by integrated approaches. At first, the…”
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Rutaecarpine Ameliorates Ethanol-Induced Gastric Mucosal Injury in Mice by Modulating Genes Related to Inflammation, Oxidative Stress and Apoptosis
Published in Frontiers in pharmacology (26-11-2020)“…Rutaecarpine (RUT), a major quinazolino carboline alkaloid compound from the dry unripe fruit (A. Juss.) T. G. Hartley, has various pharmacological effects…”
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Huanglian Jiedu Decoction Exerts Antipyretic Effect by Inhibiting MAPK Signaling Pathway
Published in Evidence-based complementary and alternative medicine (2021)“…Aim. The aim of this study was to explore the antipyretic effect and potential mechanism of Huanglian Jiedu Decoction (HLJDD) on LPS-induced fever in rats…”
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Mechanism of Paeoniflorin on ANIT-Induced Cholestatic Liver Injury Using Integrated Metabolomics and Network Pharmacology
Published in Frontiers in pharmacology (30-08-2021)“…Background: Paeoniflorin (PF), the major active compound isolated from the roots of Paeonia lactiflora Pall., has been used in the treatment of severe hepatic…”
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14
Alterations in the gut microbiota and serum metabolomics of spontaneous cholestasis caused by loss of FXR signal in mice
Published in Frontiers in pharmacology (22-05-2023)“…Farnesoid X receptor (FXR) is a key metabolic target of bile acids (BAs) and is also a target for drugs against several liver diseases. However, the…”
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Preclinical Evidence of Berberine on Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis of Animal Studies
Published in Frontiers in pharmacology (09-09-2021)“…As lifestyle and diet structure impact our health, non-alcoholic fatty liver disease (NAFLD) is prevalent all over the world. Some phytomedicines containing…”
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Treatment of Chronic Gastritis with Traditional Chinese Medicine: Pharmacological Activities and Mechanisms
Published in Pharmaceuticals (Basel, Switzerland) (01-09-2023)“…Chronic gastritis (CG) is a common clinical digestive system disease, which is not easyily cured and is prone to recurrence. Traditional Chinese medicine (TCM)…”
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Metabolomic Study of Zuojin Pill in Relieving 1-Methyl-3-nitro-1-nitrosoguanidine-Induced Chronic Atrophic Gastritis
Published in Evidence-based complementary and alternative medicine (2021)“…The classic prescription Zuojin Pill (ZJP) shows a good therapeutic effect on chronic atrophic gastritis (CAG); it is of great significance to clarify its…”
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Metabolomics Profiles Associated with the Treatment of Zuojin Pill on Patients with Chronic Nonatrophic Gastritis
Published in Frontiers in pharmacology (11-07-2022)“…Objective: Chronic nonatrophic gastritis (CNG) is the most common digestive disease. In China, Zuojin pill (ZJP) is considered an effective medicine formula…”
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Berberine inhibits IFN-γ signaling pathway in DSS-induced ulcerative colitis
Published in Saudi pharmaceutical journal (01-06-2022)“…The potential signaling pathways and core genes in ulcerative colitis (UC) were investigated in this study. Furthermore, potential mechanisms of BBR in…”
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Selective dopamine D3 receptor antagonist YQA14 inhibits morphine-induced behavioral sensitization in wild type, but not in dopamine D3 receptor knockout mice
Published in Acta pharmacologica Sinica (01-05-2019)“…Increasing preclinical evidence demonstrates that dopamine D3 receptor (D3R) antagonists are a potential option for the treatment of drug addiction. The…”
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