Search Results - "Jing, Changwen"
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Cytokine-induced killer cells as a feasible adoptive immunotherapy for the treatment of lung cancer
Published in Cell death & disease (06-03-2018)“…Most of the patients with lung cancer are diagnosed at advanced stage, and they often lose the opportunity of surgical therapy, most of whom fail to reach good…”
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2
New genetic variations discovered in KRAS wild‐type cetuximab resistant chinese colorectal cancer patients
Published in Molecular carcinogenesis (01-05-2020)“…To perform a comprehensive genomic analysis of colorectal cancer (CRC) tumor to detect genetic variants and identify novel resistant mutations associated with…”
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3
The somatic mutation landscape of Chinese Colorectal Cancer
Published in Journal of Cancer (2020)“…Colorectal cancer (CRC) is the fifth leading cause of cancer-related death in China. The incidence of Chinese CRC has increased dramatically with the changes…”
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Rupatadine-inhibited OTUD3 promotes DLBCL progression and immune evasion through deubiquitinating MYL12A and PD-L1
Published in Cell death & disease (03-08-2024)“…The obstacle to effectively treating Diffuse Large B-cell Lymphoma (DLBCL) lies in the resistance observed toward standard therapies. Identifying therapeutic…”
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5
The analysis of the circRNAs in the progress of acquired resistance to Cetuximab
Published in Precision medical sciences (01-06-2022)“…We established a Cetuximab‐resistant cell lines by high‐dose pulse method and searched for differentially expressed circular RNAs by RNA sequencing. Hundreds…”
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Comparison of droplet digital PCR and direct Sanger sequencing for the detection of the BRAF V600E mutation in papillary thyroid carcinoma
Published in Journal of clinical laboratory analysis (01-07-2019)“…The BRAF mutation status is a useful diagnostic and prognostic marker for papillary thyroid carcinoma (PTC). Although it is a commonly used method, Sanger…”
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7
LXR activation causes G1/S arrest through inhibiting SKP2 expression in MIN6 pancreatic beta cells
Published in Endocrine (01-09-2016)“…Liver X receptors (LXRs) are nuclear hormone receptors with central roles in lipid homeostasis. We previously showed that LXR activation induced aberrant lipid…”
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8
Nedaplatin reduces multidrug resistance of non-small cell lung cancer by downregulating the expression of long non-coding RNA MVIH
Published in Journal of Cancer (2020)“…Cisplatin-based chemotherapy is the standard treatment for non-small cell lung cancer (NSCLC). However, drug resistance emergences after treatment. Long…”
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The Function Role of miR-181a in Chemosensitivity to Adriamycin by Targeting Bcl-2 in Low-Invasive Breast Cancer Cells
Published in Cellular physiology and biochemistry (01-01-2013)“…Objectives: miR-181a is involved in immunity, metabolism, tumor suppression or carcinogenesis reported by many other studies. However, its role in the…”
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10
Long noncoding RNA and mRNA profiling in cetuximab‐resistant colorectal cancer cells by RNA sequencing analysis
Published in Cancer medicine (Malden, MA) (01-04-2019)“…To gain an insight into the molecular mechanisms of cetuximab resistance in colorectal cancer, we generated a cetuximab‐resistant cell line (H508/CR) and…”
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Next generation sequencing based detection of 15 target genes mutations in papillary thyroid carcinoma
Published in Precision medical sciences (01-11-2020)“…Objectives Next generation sequencing (NGS) method provided a valuable tool for a comprehensive understanding of papillary thyroid carcinoma (PTC) biology. We…”
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12
Association between mutation profiles and clinicopathological features in Chinese patients with thyroid cancer
Published in Precision medical sciences (01-09-2021)“…Recently, mutation profiles provided new insights into comprehensive understanding of TC biology by Next Generation Sequencing (NGS). We explored association…”
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13
Rare and novel GNAS gene mutations in Chinese patients with thyroid cancer
Published in Precision medical sciences (01-06-2021)“…Background A large number of novel, rare, and uncharacterized mutations in Tumors including thyroid cancer (TC) have been discovered. In this study, we…”
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14
Long noncoding RNA ZMIZ1‐AS1 promotes gefitinib resistance via binding to hnRNPA1
Published in Precision medical sciences (01-09-2021)“…To gain an insight into the molecular mechanisms of gefitinib resistance in nonsmall cell lung cancer, we screened out the long noncoding RNA related to…”
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15
Liver X receptor agonist T0901317 reverses resistance of A549 human lung cancer cells to EGFR‐TKI treatment
Published in FEBS open bio (01-01-2017)“…Epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) is effective in lung cancer patients carrying sensitive EGFR mutations. In this study, we…”
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16
Huntingtin-associated protein 1: A potential biomarker of breast cancer
Published in Oncology reports (01-05-2013)“…It is reported that patients with Huntington's disease (HD) have a low incidence of cancer. In this study, we investigated the expression of…”
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17
Resveratrol prevents interleukin-1 β-induced dysfunction of pancreatic β-cells
Published in Journal of biomedical research (01-09-2010)“…Objective:Interleukin-1β(IL-1β)plays an important role in the development of type 1 and type 2 diabetes mellitus.Resveratrol,a polyphenol,is known to have a…”
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18
Exosome-mediated gefitinib resistance in lung cancer HCC827 cells via delivery of miR-21
Published in Oncology letters (01-06-2018)“…Acquired resistance to gefitinib remains a major challenge in cancer treatment. In the present study, the effect of exosomes on the transmission of gefitinib…”
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Next‑generation sequencing‑based detection of EGFR, KRAS, BRAF, NRAS, PIK3CA, Her‑2 and TP53 mutations in patients with non‑small cell lung cancer
Published in Molecular medicine reports (01-08-2018)“…In recent years, the incidence of non‑small cell lung cancer (NSCLC) has become the highest lethal rate of cancer worldwide. Molecular assays of EGFR, KRAS,…”
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20
CLASRP oncogene as a novel target for colorectal cancer
Published in Functional & integrative genomics (01-09-2023)“…Clk4-associated serine/arginine-rich protein ( CLASRP ), an alternative splicing regulator, may be involved in the development and progression of cancer by…”
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