Search Results - "Jin, Yu Qin"
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A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variants
Published in eLife (25-08-2022)“…Large-scale populations in the world have been vaccinated with COVID-19 vaccines, however, breakthrough infections of SARS-CoV-2 are still growing rapidly due…”
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Design of a mutation-integrated trimeric RBD with broad protection against SARS-CoV-2
Published in Cell discovery (15-02-2022)“…The continuous emergence of SARS-CoV-2 variants highlights the need of developing vaccines with broad protection. Here, according to the immune-escape…”
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Mutating a flexible region of the RSV F protein can stabilize the prefusion conformation
Published in Science (American Association for the Advancement of Science) (27-09-2024)“…The respiratory syncytial virus (RSV) fusion (F) glycoprotein is highly immunogenic in its prefusion (pre-F) conformation. However, the protein is unstable,…”
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Efficient and general synthesis of oxazino[4,3-a]indoles by cascade addition-cyclization reactions of (1H-indol-2-yl)methanols and vinyl sulfonium salts
Published in Chemical communications (Cambridge, England) (01-01-2011)“…An efficient and general approach to oxazino[4,3-a]indole architectures is described. The addition-cyclization cascade of (1H-indol-2-yl)methanols with vinyl…”
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Dalbergioidin (DAL) protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-07-2017)“…Reactive oxygen species (ROS) is a pivotal pathogenic factor in the development of osteoporosis. Dalbergioidin (DAL) can be isolated from Uraria crinite , an…”
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Feasible endoscopic therapy for early gastric cancer
Published in World journal of gastroenterology : WJG (21-12-2015)“…AIM To analyze the relationship between lymphnode metastasis and clinical pathology of early gastriccancer (EGC) in order to provide criteria for a…”
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Design of hepadnavirus core protein-based chimeric virus-like particles carrying epitopes from respiratory syncytial virus
Published in npj vaccines (19-03-2024)“…Respiratory syncytial virus (RSV) is one of the most important pathogens causing respiratory tract infection in humans, especially in infants and the elderly…”
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The Efficiency and Complications of ESD and ESTD in the Treatment of Large Esophageal Mucosal Lesions
Published in Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban (01-11-2015)“…To study the efficiency and complications of endoscopic submucosal dissection (ESD) and endoscopic submucosal tunnel dissection (ESTD) in the treatment of…”
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E484K mutation in SARS-CoV-2 RBD enhances binding affinity with hACE2 but reduces interactions with neutralizing antibodies and nanobodies: Binding free energy calculation studies
Published in Journal of molecular graphics & modelling (01-12-2021)“…The pandemic of the COVID-19 disease caused by SARS-CoV-2 has led to more than 200 million infections and over 4 million deaths worldwide. The progress in the…”
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Factors Associated with Successful Submucosal Tunneling Endoscopic Resection Treatment for Upper Gastrointestinal Submucosal Tumors
Published in Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban (01-11-2015)“…To determine the influence of location, depth and size of upper gastrointestinal (GI) submucosal tumors (SMTs) on the success of submucosal tunneling…”
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Correlation Between Endoscopic Macroscopic Type and Depth of Tumor Invasion for Superficial Adenocarcinoma of Esophagogastric Junction
Published in Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban (01-11-2015)“…To investigate the clinicopathologic characteristics of superficial adenocarcinoma of esophagogastric junction (AEG), and to analyze the relationship between…”
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Homogeneous and heterogeneous ionic liquids catalyze CO2 cycloaddition reaction
Published in Journal of molecular structure (15-02-2025)“…•Regulation of CO2 capture process by imidazole based ionic liquids.•Polyionic liquid membrane catalyzed CO2 conversion in membrane reactor.•DFT calculation of…”
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Repair of calvarial defect using a tissue-engineered bone with simvastatin-loaded β-tricalcium phosphate scaffold and adipose derived stem cells in rabbits
Published in Shanghai kou qiang yi xue (01-08-2013)“…The osteogenic-angiogenic differentiation effects of simvastatin (Sim) were explored on adipose tissue-derived stem cells (ASCs). A tissue-engineered bone with…”
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Chimeric virus-like particles of human norovirus constructed by structure-guided epitope grafting elicit cross-reactive immunity against both GI.1 and GII.4 genotypes
Published in Journal of virology (31-10-2023)“…Human norovirus (HuNoV) is highly infectious and can result in severe illnesses in the elderly and children. So far, there is no effective antiviral drug to…”
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Optimal control strategy for VSC-based systems under unbalanced network conditions
Published in 2016 IEEE International Conference on Power System Technology (POWERCON) (01-09-2016)“…This study presents an optimization control strategy to improve the ride-through capability of voltage source converter-based high voltage direct current…”
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Change of activity of serum paraoxonase in patients with acute organophosphorus poisoning
Published in Zhonghua laodong weisheng zhiyebing zazhi (01-10-2007)Get more information
Journal Article -
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Dalbergioidin (DAL) protects MC3T3-E1 osteoblastic cells against H 2 O 2 -induced cell damage through activation of the PI3K/AKT/SMAD1 pathway
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-07-2017)“…Reactive oxygen species (ROS) is a pivotal pathogenic factor in the development of osteoporosis. Dalbergioidin (DAL) can be isolated from Uraria crinite, an…”
Get full text
Journal Article -
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Safety and immunogenicity of a mosaic vaccine booster against Omicron and other SARS-CoV-2 variants: a randomized phase 2 trial
Published in Signal transduction and targeted therapy (03-01-2023)“…An ongoing randomized, double-blind, controlled phase 2 trial was conducted to evaluate the safety and immunogenicity of a mosaic-type recombinant vaccine…”
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Inflammation: a mechanism of depression
Published in Neuroscience bulletin (01-06-2014)“…In recent decades, major depression has become more prevalent and research has shown that immune activation and cytokine production may be involved. This…”
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