Search Results - "Jin, Yonghui"

Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva by Hino, Kyosuke, Horigome, Kazuhiko, Nishio, Megumi, Komura, Shingo, Nagata, Sanae, Zhao, Chengzhu, Jin, Yonghui, Kawakami, Koichi, Yamada, Yasuhiro, Ohta, Akira, Toguchida, Junya, Ikeya, Makoto

“…Fibrodysplasia ossificans progressiva (FOP) is a rare and intractable disease characterized by extraskeletal bone formation through endochondral ossification…”
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Activation of NADPH/ROS pathway contributes to angiogenesis through JNK signaling in brain endothelial cells by Wang, Zairan, Yang, Jiping, Qi, Jinchong, Jin, Yonghui, Tong, Liyan

“…Recent evidences have shown that reactive oxygen species (ROS) are involved in regulating angiogenesis and preventing tissue injury. However, the precise…”
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Prophylactic treatment of rapamycin ameliorates naturally developing and episode -induced heterotopic ossification in mice expressing human mutant ACVR1 by Maekawa, Hirotsugu, Kawai, Shunsuke, Nishio, Megumi, Nagata, Sanae, Jin, Yonghui, Yoshitomi, Hiroyuki, Matsuda, Shuichi, Toguchida, Junya

“…Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal-dominant disease characterized by heterotopic ossification (HO) in soft tissues and caused by a…”
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Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes by Jin, Yonghui, Elalaf, Hassan, Watanabe, Makoto, Tamaki, Sakura, Hineno, Sho, Matsunaga, Kazuhito, Woltjen, Knut, Kobayashi, Yukiko, Nagata, Sanae, Ikeya, Makoto, Kato, Jr, Tomohisa, Okamoto, Takeshi, Matsuda, Shuichi, Toguchida, Junya

“…Somatic mutations in the isocitrate dehydrogenase (IDH)1/2 genes endow encoding proteins with neomorphic activity to produce the potential oncometabolite,…”
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3D osteogenic differentiation of human iPSCs reveals the role of TGFβ signal in the transition from progenitors to osteoblasts and osteoblasts to osteocytes by Kawai, Shunsuke, Sunaga, Junko, Nagata, Sanae, Nishio, Megumi, Fukuda, Masayuki, Kamakura, Takeshi, Sun, Liping, Jin, Yonghui, Sakamoto, Satoko, Watanabe, Akira, Matsuda, Shuichi, Adachi, Taiji, Toguchida, Junya

“…Although the formation of bone-like nodules is regarded as the differentiation process from stem cells to osteogenic cells, including osteoblasts and…”
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SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier by Tamaki, Sakura, Fukuta, Makoto, Sekiguchi, Kazuya, Jin, Yonghui, Nagata, Sanae, Hayakawa, Kazuo, Hineno, Sho, Okamoto, Takeshi, Watanabe, Makoto, Woltjen, Knut, Ikeya, Makoto, Kato, Jr, Tomohisa, Toguchida, Junya

“…The prevalence and specificity of unique fusion oncogenes are high in a number of soft tissue sarcomas (STSs). The close relationship between fusion genes and…”
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Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs by Maekawa, Hirotsugu, Jin, Yonghui, Nishio, Megumi, Kawai, Shunsuke, Nagata, Sanae, Kamakura, Takeshi, Yoshitomi, Hiroyuki, Niwa, Akira, Saito, Megumu K., Matsuda, Shuichi, Toguchida, Junya

“…Background Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized by progressive heterotopic ossification (HO) in soft tissues due…”
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Distinct muscle regenerative capacity of human induced pluripotent stem cell-derived mesenchymal stromal cells in Ullrich congenital muscular dystrophy model mice by Yokomizo-Goto, Megumi, Takenaka-Ninagawa, Nana, Zhao, Chengzhu, Bourgeois Yoshioka, Clémence Kiho, Miki, Mayuho, Motoike, Souta, Inada, Yoshiko, Zujur, Denise, Theoputra, William, Jin, Yonghui, Toguchida, Junya, Ikeya, Makoto, Sakurai, Hidetoshi

“…Ullrich congenital muscular dystrophy (UCMD) is caused by a deficiency in type 6 collagen (COL6) due to mutations in COL6A1, COL6A2, or COL6A3. COL6 deficiency…”
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In vitro bone-like nodules generated from patient-derived iPSCs recapitulate pathological bone phenotypes by Kawai, Shunsuke, Yoshitomi, Hiroyuki, Sunaga, Junko, Alev, Cantas, Nagata, Sanae, Nishio, Megumi, Hada, Masataka, Koyama, Yuko, Uemura, Maya, Sekiguchi, Kazuya, Maekawa, Hirotsugu, Ikeya, Makoto, Tamaki, Sakura, Jin, Yonghui, Harada, Yuki, Fukiage, Kenichi, Adachi, Taiji, Matsuda, Shuichi, Toguchida, Junya

“…The recapitulation of bone formation via the in vitro generation of bone-like nodules is frequently used to understand bone development. However, current…”
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Genetically matched human iPS cells reveal that propensity for cartilage and bone differentiation differs with clones, not cell type of origin by Nasu, Akira, Ikeya, Makoto, Yamamoto, Takuya, Watanabe, Akira, Jin, Yonghui, Matsumoto, Yoshihisa, Hayakawa, Kazuo, Amano, Naoki, Sato, Shingo, Osafune, Kenji, Aoyama, Tomoki, Nakamura, Takashi, Kato, Tomohisa, Toguchida, Junya

“…For regenerative therapy using induced pluripotent stem cell (iPSC) technology, cell type of origin to be reprogrammed should be chosen based on accessibility…”
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Removal of Methylene Blue by Crosslinked Egg White Protein/Graphene Oxide Bionanocomposite Aerogels by Jin, Yonghui, Du, Qiuju, Li, Yanhui, Zhang, Yang, Chen, Bing, Wang, Mingzhen, Chen, Kewei, Sun, Yaohui, Zhao, Shiyong, Jing, Zhenyu

“…Egg white protein is a non-toxic and biodegradable biopolymer that forms a gel easily via simple thermal denaturation treatment. A novel aerogel on the basis…”
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Collagen X Is Dispensable for Hypertrophic Differentiation and Endochondral Ossification of Human iPSC‐Derived Chondrocytes by Kamakura, Takeshi, Jin, Yonghui, Nishio, Megumi, Nagata, Sanae, Fukuda, Masayuki, Sun, Liping, Kawai, Shunsuke, Toguchida, Junya

“…ABSTRACT Collagen X is a non‐fibril collagen produced by hypertrophic chondrocytes and was believed to associate with the calcification process of growth plate…”
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Histone Modifiers, YY1 and p300, Regulate the Expression of Cartilage-specific Gene, Chondromodulin-I, in Mesenchymal Stem Cells by Aoyama, Tomoki, Okamoto, Takeshi, Fukiage, Kenichi, Otsuka, Seiji, Furu, Moritoshi, Ito, Kinya, Jin, Yonghui, Ueda, Michiko, Nagayama, Satoshi, Nakayama, Tomitaka, Nakamura, Takashi, Toguchida, Junya

“…Elucidating the regulatory mechanism for tissue-specific gene expression is key to understanding the differentiation process. The chondromodulin-I gene (ChM-I)…”
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In vitro bone-like nodules generated from patient-derived iPSCs recapitulate pathological bone phenotypes by Kawai, Shunsuke, Yoshitomi, Hiroyuki, Sunaga, Junko, Alev, Cantas, Nagata, Sanae, Nishio, Megumi, Hada, Masataka, Koyama, Yuko, Uemura, Maya, Sekiguchi, Kazuya, Maekawa, Hirotsugu, Ikeya, Makoto, Tamaki, Sakura, Jin, Yonghui, Harada, Yuki, Fukiage, Kenichi, Adachi, Taiji, Matsuda, Shuichi, Toguchida, Junya

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Absence of Oncogenic Mutations of RAS Family Genes in Soft Tissue Sarcomas of 100 Japanese Patients by YONGHUI JIN, SHIMA, Yasuko, FURU, Moritoshi, AOYAMA, Tomoki, NAKAMATA, Takeharu, NAKAYAMA, Tomitaka, NAKAMURA, Takashi, TOGUCHIDA, Junya

“…Background: Activating point mutations of genes of the RAS family (KRAS, HRAS and NRAS genes) are frequently found in carcinomas, but their prevalence in…”
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A novel method to isolate mesenchymal stem cells from bone marrow in a closed system using a device made by nonwoven fabric by Ito, Kinya, Aoyama, Tomoki, Fukiage, Kenichi, Otsuka, Seiji, Furu, Moritoshi, Jin, Yonghui, Nasu, Akira, Ueda, Michiko, Kasai, Yasunari, Ashihara, Eishi, Kimura, Shinya, Maekawa, Taira, Kobayashi, Akira, Yoshida, Shinya, Niwa, Hideo, Otsuka, Takanobu, Nakamura, Takashi, Toguchida, Junya

“…Bone marrow stromal cells (BMSCs) include cells with multidirectional differentiation potential described as mesenchymal stem cells. For clinical use, it is…”
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Unexpected Behavior in Thermal Conductivity of Confined Monolayer Water by Zhao, Zhixiang, Jin, Yonghui, Zhou, Runfeng, Sun, Chengzhen, Huang, Xiang

“…Monolayer water can be formed under extreme confinement and will present distinctive thermodynamic properties compared with bulk water. In this work, we…”
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Polydopamine coating for enhanced electrostatic adsorption of methylene blue by multiwalled carbon nanotubes in alkaline environments by Zhang, Jie, Li, Yanhui, Wang, Xinxin, Zhao, Shiyong, Du, Qiuju, Pi, Xinxin, Jing, Zhenyu, Jin, Yonghui

“…[Display omitted] The removal of dye molecules in alkaline environments is an issue that should receive increased attention. In this study, the interaction…”
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Preparation of MIL-88A micro/nanocrystals with different morphologies in different solvents for efficient removal of Congo red from water: Synthesis, characterization, and adsorption mechanisms by Zhao, Shiyong, Li, Yanhui, Wang, Mingzhen, Chen, Bing, Zhang, Yang, Sun, Yaohui, Chen, Kewei, Du, Qiuju, Jing, Zhenyu, Jin, Yonghui

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A robust approach for the decomposition of high-energy-consuming industrial loads with deep learning by Cui, Jia, Jin, Yonghui, Yu, Renzhe, Okoye, Martin Onyeka, Li, Yang, Yang, Junyou, Wang, Shunjiang

“…The knowledge of the users’ electricity consumption pattern is an important coordinating mechanism between the utility company and the electricity consumers in…”
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